Pharmaceutical Reference Standards / Impurity Standards

Ticagrelor
Triafluocyl
Ticagrelor Impurity G
Ticagrelor Impurity 105
Ticagrelor EP Impurity A
Ticagrelor Amine Impurity Hydrochloride
Ticagrelor Related Compound 21
Ticagrelor Impurity M
Ticagrelor 7-Hydroxy Impurity
Ticagrelor Related Compound 63 Hydrochloride
(1S,2R)-2-(4-fluorophenyl)cyclopropanamine Hydrochloride
Ticagrelor EP Impurity C
Ticagrelor Related Compound 14
Ticagrelor Related Compound 16
Ticagrelor EP Impurity D
Ticagrelor EP Impurity B
Ticagrelor EP Impurity E Hydrochloride
Ticagrelor Impurity 78
2,3-Difluoro Ticagrelor
Ticagrelor Impurity N
Ticagrelor Related Compound 57 (TIC 2A Desacetonide)
Ticagrelor Related Compound 76
Tricagrelor Impurity 4
Ticagrelor EP Impurity E Maleate
4-chloro-5-nitro-2-(propylsulfanyl)pyrimidine
4-methoxy-5-nitro-2-(propylthio)pyrimidine
Ticagrelor Related Compound 69
6-chloro-5-nitro-2-(propylthio)pyrimidin-4-ol
Ticagrelor Impurity 102
(1S,2R)-2-(3,4-difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate
(1R,2R)-2-(3,4-difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate
Ticagrelor Impurity 131
Ticagrelor IP Impurity D
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine
Ticagrelor Related Compound 6 Hydrochloride
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine
Ticagrelor Pyrimidine Dimer
Ticagrelor Impurity 6
rac-(1R,2S)-2-(2,3-difluorophenyl)cyclopropan-1-amine hydrochloride
trans-[2-(4-Fluorophenyl)cyclopropyl]amine Hydrochloride
2-chloro-1-(2,3-difluorophenyl)ethanone
Ticagrelor EP Impurity E Hydrochloride
Ticagrelor EP Impurity E
trans-rel-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
Ticagrelor IP Impurity C
(1R,2S)-2-(3-chloro-4-fluorophenyl)cyclopropan-1-amine
ethyl 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate
Ticagrelor Intermediate
Ticagrelor Impurity 134
Ticagrelor Impurity 83
Ticagrelor Related Compound 1
2-(((3aS,4R,6S,6aR)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol Tartrate
6-Chloro-5-nitro-2-(propylthio)-4(1H)-pyrimidinone
Ticagrelor 4-desfluoro
Ticagrelor Related Compound 99
Ticagrelor Related Compound 17
Ticagrelor Enantiomer Impurity
Ticagrelor Impurity Q
N-Nitroso Ticagrelor
Ticagrelor Impurity 85
2-(((3aS,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
3-((2S,4S)-4-mercapto-1-(((4-nitrobenzyl)oxy)carbonyl)pyrrolidine-2-carboxamido)benzoic acid
2-hydroxyethyl2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate
(1R,2S)-2-(4-fluorophenyl)cyclopropanamine
(1S,2R,3S,4R)-4-aminocyclopentane-1,23-triol
Ticagrelor Impurity 1
6-chloro-2-(propylthio)pyrimidin-4-amine
Ticagrelor Related Compound 62
Ticagrelor Related Compound 70 Hydrochloride
2-((3-((4-amino-3,5-dichlorophenyl)thio)propyl)thio)-4,6-dichloropyrimidin-5-amine
4,6-dibromo-5-nitro-2-(propylthio)pyrimidine
4-chloro-6-methoxy-2-(propylthio)pyrimidin-5-amine
Ticagrelor Impurity 66
Ticagrelor Impurity 90
2-(2-(Benzyloxy)ethoxy)ethyl,4-methylbenzenesulfonate
Ticagrelor Impurity 100
N-Nitroso Ticagrelor EP Impurity D
Ticagrelor formamide Impurity
Ticagrelor Related Compound 38 D Tartaric acid
(1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarbonyl azide
2-Thiobarbituric Acid
Ticagrelor Related Compound 2
2-[[(3aS,4R,6S,6aR)-4-Aminotetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol Oxalate
(1R, 2R)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
(1S,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
(1R,2S)-2-(2,4-Difluorophenyl)cyclopropanamine
(1R,2R)-2-(2,4-Difluorophenyl)cyclopropanamine
(1S,2S)-2-(2,4-difluorophenyl)cyclopropanamine
(1S,2R)-2-(2,4-difluorophenyl)cyclopropanamine
(1R,2S)-2-(2,3-Difluorophenyl)cyclopropanamine
Ticagrelor Impurity 129
(1S,2S)-2-(2,3-difluorophenyl)cyclopropanamine
(1S,2R)-2-(2,3-difluorophenyl)cyclopropanamine
Ticagrelor Impurity 63
(1R,2R)-2-(3,5-Difluorophenyl)cyclopropanamine
(1S,2S)-2-(3,5-Difluorophenyl)cyclopropanamine
(1S,2R)-2-(3,5-Difluorophenyl)cyclopropanamine
(1R,2S)-2-(2,5-difluorophenyl)cyclopropanamine
(1R,2R)-2-(2,5-difluorophenyl)cyclopropanamine
(1S,2S)-2-(2,5-difluorophenyl)cyclopropanamine
(1S,2R)-2-(2,5-difluorophenyl)cyclopropanamine
(1R,2S)-2-(2,6-Difluorophenyl)cyclopropanamine
(1R,2R)-2-(2,6-Difluorophenyl)cyclopropanamine
(1S,2S)-2-(2,6-Difluorophenyl)cyclopropanamine
(1S,2R)-2-(2,6-Difluorophenyl)cyclopropanamine
Ticagrelor Related Compound 27 Oxalate
Ticagrelor Impurity 111
Ticagrelor KSM-II Standard
Cyclopropanamine-2-(3,4-difluorophenyl)-(1R,2S)-(2R,3R)-2,3-dihydroxybutanedioate
Ticagrelor P0Z3 Impurity
Ticagrelor P0Z13 Impurity
Ticagrelor Related Compound 10
Ticagrelor Impurity 192
Ticagrelor Acetyl Impurity
Ticagrelor Related Compound 75
Ticagrelor Impurity 125
Methyl2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)acetate oxalate
Ticagrelor KSM-II t-Butyl ester
Ticagrelor Related Compound 56
Ticagrelor Hydrochloride
(S)-2-(3,4-Difluorophenyl)oxirane
Ticagrelor (1S,2S,3S,5R) Isomer
Ticagrelor Impurity 68
Ticagrelor Impurity 39
Ethyl2-((3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)glycinate
Ticagrelor Nitroso Impurity 16
N-Nitroso Ticagrelor EP Impurity C
Ticagrelor Nitroso Impurity 8
Ticagrelor Nitroso Impurity 15
Ticagrelor Form II
2-(3,5-difluorophenyl)cyclopropanamine hydrochloride salt
Ticagrelor Impurity 93
Ticagrelor Related Compound 91
Ticagrelor Related Compound 27
Ticagrelor Impurity 92
Ticagrelor Nitroso Impurity 19
Ticagrelor Nitroso Impurity 22
Ticagrelor Impurity 145
Ticagrelor Impurity 144
(3aR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol
Ticagrelor Impurity 148
Ticagrelor Impurity 146
Ticagrelor Impurity 147
Ticagrelor EP Impurity E (Racemic mixture )
(1R, 2S)-2-(3-ethoxy-4-fluorophenyl)cyclopropanamine hydrochloride
(1R,2R)-2-(4-Fluorophenyl)cyclopropanamine hydrochloride
Ticagrelor Impurity
Ticagrelor Impurity 82
Ticagrelor Related Compound 68
Ticagrelor Impurity 152
Ticagrelor Impurity 153
Ticagrelor Impurity 156
Ticagrelor Impurity 158
rel-(1R,2R)-2-(3,4-Difluorophenyl)cyclopropan-1-amine hydrochloride
Ticagrelor Nitroso Impurity 5
2-(Propylthio)pyrimidine-4,6-diol
2,3-O-Isopropylidene-D-ribofuranose
rel-(1R,2S)-2-(4-Fluorophenyl)cyclopropan-1-amine
Ticagrelor Impurity 149
Ticagrelor Impurity 14
Ticagrelor Impurity 163
Ticagrelor Impurity 164
2-(3-Fluoro-4-methoxyphenyl)cyclopropanamine
Ticagrelor Impurity 161
Ticagrelor Impurity 162
Ticagrelor Nitroso Impurity 17
Ticagrelor Impurity 67
Ticagrelor Related Compound 49
Benzyl ((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)carbamate
Ticagrelor Enantiomer Nitroso Impurity
N-Nitroso Ticagrelor Impurity E
Ticagrelor Impurity 171
Ticagrelor Impurity 172
Ticagrelor Impurity 130
Ticagrelor Impurity 132
Ticagrelor Impurity 133
Ticagrelor Impurity 134
Ticagrelor Nitroso Impurity 13
O-Tert-Butyl Ticagrelor Impurity
Ticagrelor Impurity 177
Ticagrelor Impurity 178
Ticagrelor Impurity 176
Ticagrelor Impurity 181
Ticagrelor Impurity 182
Ticagrelor Impurity 183
Ticagrelor Related Compound 74
Ticagrelor Impurity L (Mixture of Diastereomers)
Ticagrelor Impurity 135
Ticagrelor Sulfonate Impurity
Ticagrelor Impurity 188
Ticagrelor Impurity 123
Ticagrelor Impurity 187
Ticagrelor Impurity 166
Ticagrelor Related Compound 96
Ticagrelor Impurity 5
Ticagrelor (1R,2R,3R,5S) Isomer
Ticagrelor (1R,2R,3S,5S) Isomer
Ticagrelor Impurity 193
Ticagrelor Impurity 196
Ticagrelor Impurity 197
Ticagrelor Impurity 198
Ticagrelor Impurity 195
Ticagrelor Impurity 199
Ticagrelor Impurity 200
N-Nitroso Ticagrelor Impurity 1
Ticagrelor (1R,2R)-isomer
Ticagrelor Impurity 201
Ticagrelor Impurity 202
Ticagrelor Related Compound 73
Ticagrelor Impurity 136
Ticagrelor Impurity 137
Ticagrelor Impurity 138
Ticagrelor Impurity B
Ticagrelor Impurity 17
Ticagrelor Related Compound 3
Ticagrelor Impurity 3
Ticagrelor Impurity 4
Ticagrelor Impurity 21
Ticagrelor Impurity 22
Ticagrelor Impurity 23
Ticagrelor Impurity 24
Ticagrelor Impurity 25
Ticagrelor Impurity 26
Ticagrelor Impurity 27
Ticagrelor Impurity 28
Ticagrelor Impurity 29
Ticagrelor Impurity 30
Ticagrelor Impurity 31
Ticagrelor Impurity 32
Ticagrelor Impurity 33
Ticagrelor Impurity 34
Ticagrelor Impurity 36
Ticagrelor Impurity 37
Ticagrelor Impurity 38
Ticagrelor Impurity 40
Ticagrelor Impurity 41
Ticagrelor Impurity 42
Ticagrelor Impurity 22
Ticagrelor Impurity 23
Ticagrelor Related Compound 7
Ticagrelor Impurity 35
Ticagrelor Impurity 43
Ticagrelor Impurity 44
Ticagrelor Impurity 45
Ticagrelor impurity 2
Ticagrelor Impurity 47
Ticagrelor Form I
Ticagrelor Form III
Ticagrelor Form IV
Ticagrelor Novel Form
Ticagrelor (Amorphous form)
Tricagrelor Impurity 1
N-Nitroso Ticagrelor Impurity 2
Ticagrelor Impurity 46
Ticagrelor Impurity 48
Ticagrelor Impurity 7
Ticagrelor Impurity 135
Ticagrelor Impurity 8
Ticagrelor Impurity 9
Ticagrelor Impurity 10
Ticagrelor Impurity 49
Ticagrelor impurity 2
Ticagrelor impurity 50

Metabolites

Ticagrelor O-Glucuronide
Ticagrelor Related Compound 97

Isotope Labelled Compounds

Ticagrelor -D7
Ticagrelor Metabolite-D7