Olanzapine Related Compounds & Impurities

Olanzapine is an atypical antipsychotic with multi-receptor antagonism, used for schizophrenia, bipolar mania and treatment-resistant depression.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Olanzapine reference standards, pharmacopeial and non-pharmacopeial Olanzapine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Olanzapine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Olanzapine
Olanzapine
  • CAT. No.O010000
  • CAS. No.132539-06-1
  • Mol. F.C17H20N4S
  • Mol. W.312.43 g/mol
  • Stock Status:Instock
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Olanzapine Form II (Crystalline)
Olanzapine Form II (Crystalline)
  • CAT. No.O010000A
  • CAS. No.132539-06-1
  • Mol. F.C17H20N4S
  • Mol. W.312.43 g/mol
  • Stock Status:Instock
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Olanzapine Form I
Olanzapine Form I
  • CAT. No.O010000B
  • CAS. No.132539-06-1
  • Mol. F.C17H20N4S
  • Mol. W.312.43 g/mol
  • Stock Status:Instock
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Olanzapine pamoate monohydrate
Olanzapine pamoate monohydrate
  • CAT. No.O010000D
  • CAS. No.221373-18-8
  • Mol. F.C23H16O6.C17H20N4S.H2O
  • Mol. W.718.82 g/mol
  • Stock Status:Instock
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Desmethyl Olanzapine
Desmethyl Olanzapine
  • CAT. No.O010001
  • CAS. No.161696-76-0
  • Mol. F.C16H18N4S
  • Mol. W.298.41 g/mol
  • Stock Status:Instock
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Olanzapine EP Impurity B
Olanzapine EP Impurity B
  • CAT. No.O010002
  • CAS. No.221176-49-4
  • Mol. F.C12H10N2OS
  • Mol. W.230.29 g/mol
  • Stock Status:Instock
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Olanzapine EP Impurity C
Olanzapine EP Impurity C
  • CAT. No.O010003
  • CAS. No.719300-59-1
  • Mol. F.C18H22Cl2N4S
  • Mol. W.397.37 g/mol
  • Stock Status:Instock
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Olanzapine EP Impurity D
Olanzapine EP Impurity D
  • CAT. No.O010004
  • CAS. No.174794-02-6
  • Mol. F.C17H20N4OS
  • Mol. W.328.43 g/mol
  • Stock Status:Instock
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Olanzapine EP Impurity D Hydrochloride
Olanzapine EP Impurity D Hydrochloride
  • CAT. No.O010004A
  • CAS. No.NA
  • Mol. F.C17H21N4OSCl
  • Mol. W.364.89 g/mol
  • Stock Status:Under Synthesis
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Olanzapine Amine Impurity
Olanzapine Amine Impurity
  • CAT. No.O010006
  • CAS. No.138564-60-0
  • Mol. F.C12H12ClN3S
  • Mol. W.265.76 g/mol
  • Stock Status:Instock
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Olanzapine Lactam
Olanzapine Lactam
  • CAT. No.O010007
  • CAS. No.1017241-34-7
  • Mol. F.C17H20N4O2
  • Mol. W.312.37 g/mol
  • Stock Status:Instock
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Olanzapine EP Impurity A
Olanzapine EP Impurity A
  • CAT. No.O010008
  • CAS. No.138564-59-7
  • Mol. F.C12H9N3O2S
  • Mol. W.259.28 g/mol
  • Stock Status:Instock
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Olanzapine Thiolactum
Olanzapine Thiolactum
  • CAT. No.O010009
  • CAS. No.1017241-36-9
  • Mol. F.C17H20N4OS
  • Mol. W.328.43g/mol
  • Stock Status:Instock
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Olanzapine Thiolactum
Olanzapine Thiolactum
  • CAT. No.O010009A
  • CAS. No.1017241-36-9
  • Mol. F.C17H20N4OS
  • Mol. W.328.43 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethyl N-Ethyl Olanzapine
N-Desmethyl N-Ethyl Olanzapine
  • CAT. No.O010010
  • CAS. No.1355034-54-6
  • Mol. F.C18H22N4S
  • Mol. W.326.43 g/mol
  • Stock Status:Instock
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Olanzapine Impurity 1
Olanzapine Impurity 1
  • CAT. No.O010011
  • CAS. No.873895-41-1
  • Mol. F.C12H11N3S
  • Mol. W.229.30 g/mol
  • Stock Status:Instock
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Olanzapine Impurity 1 Acetate
Olanzapine Impurity 1 Acetate
  • CAT. No.O010011A
  • CAS. No.NA
  • Mol. F.C12H11N3S.C2H4O2
  • Mol. W.289.35 g/mol
  • Stock Status:Limited Stock
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2-Amino-5-Methyl-3-Thiophenecarbonitrile
2-Amino-5-Methyl-3-Thiophenecarbonitrile
  • CAT. No.O010012
  • CAS. No.138564-58-6
  • Mol. F.C6H6N2S
  • Mol. W.138.19 g/mol
  • Stock Status:Instock
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O-Fluoronitrobenzene
O-Fluoronitrobenzene
  • CAT. No.O010014
  • CAS. No.1493-27-2
  • Mol. F.C6H4FNO2
  • Mol. W.141.10 g/mol
  • Stock Status:Instock
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Methyl 2-amino-5-methylthiophene-3-carboxylate
Methyl 2-amino-5-methylthiophene-3-carboxylate
  • CAT. No.O010015
  • CAS. No.19369-53-0
  • Mol. F.C7H9NO2S
  • Mol. W.171.22 g / mol
  • Stock Status:Instock
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1,3-Dicyclohexyl-3-hydroxy-1-propanone
1,3-Dicyclohexyl-3-hydroxy-1-propanone
  • CAT. No.O010017
  • CAS. No.NA
  • Mol. F.C15H26O2
  • Mol. W.238.37 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine N-Formyl Impurity
Olanzapine N-Formyl Impurity
  • CAT. No.O010018
  • CAS. No.639460-79-0
  • Mol. F.C17H18N4OS
  • Mol. W.326.42 g/mol
  • Stock Status:Instock
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Olanzapine Impurity 13
Olanzapine Impurity 13
  • CAT. No.O010019
  • CAS. No.1070876-09-3
  • Mol. F.C28H26N6S2
  • Mol. W.510.68 g/mol
  • Stock Status:Custom Synthesis
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1,1-dimethyl-4-(2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine)piperaziniumion
1,1-dimethyl-4-(2-methyl-10H-thieno[2,3-b][1,5]benzodiazepine)piperaziniumion
  • CAT. No.O010020
  • CAS. No.NA
  • Mol. F.C18H25N4S
  • Mol. W.329.48 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 12 Hydrochloride
Olanzapine Impurity 12 Hydrochloride
  • CAT. No.O010022
  • CAS. No.NA
  • Mol. F.C18H15ClN4O2S
  • Mol. W.386.56 g/mol
  • Stock Status:Limited Stock
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Olanzapine Amino Methanone Impurity
Olanzapine Amino Methanone Impurity
  • CAT. No.O010023
  • CAS. No.138564-61-1
  • Mol. F.C17H22N4OS
  • Mol. W.330.45 g/mol
  • Stock Status:Instock
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Olanzapine Thiohydroxymethylidene
Olanzapine Thiohydroxymethylidene
  • CAT. No.O010024
  • CAS. No.1320360-86-8
  • Mol. F.C15H18N4OS
  • Mol. W.302.39 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Acetoxymethylidene (Imp 4)
Olanzapine Acetoxymethylidene (Imp 4)
  • CAT. No.O010025
  • CAS. No.1320360-87-9
  • Mol. F.C17H20N4O2S
  • Mol. W.344.43 g/mol
  • Stock Status:Under Synthesis
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N-Demethyl-N-formylolanzapine
N-Demethyl-N-formylolanzapine
  • CAT. No.O010026
  • CAS. No.639460-79-0
  • Mol. F.C17H18N4OS
  • Mol. W.326.42 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 15
Olanzapine Impurity 15
  • CAT. No.O010027
  • CAS. No.935272-10-9
  • Mol. F.C18H20N4OS
  • Mol. W.340.44 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 16
Olanzapine Impurity 16
  • CAT. No.O010028
  • CAS. No.1797009-17-6
  • Mol. F.C17H20N4S
  • Mol. W.312.43 g/mol
  • Stock Status:Custom Synthesis
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2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-ol
2-methyl-10H-thieno[2,3-b][1,5]benzodiazepin-4-ol
  • CAT. No.O010029
  • CAS. No.NA
  • Mol. F.C12H10N2OS
  • Mol. W.230.29 g/mol
  • Stock Status:Custom Synthesis
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Bis-[10(2-methyl-4H-3-thia-4,9-diazabenzo[f]azulene)]-1,4-piperazine
Bis-[10(2-methyl-4H-3-thia-4,9-diazabenzo[f]azulene)]-1,4-piperazine
  • CAT. No.O010030
  • CAS. No.1070876-09-3
  • Mol. F.C28H26N6S2
  • Mol. W.510.68 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine N-Formyl
Olanzapine N-Formyl
  • CAT. No.O010031
  • CAS. No.639460-79-0
  • Mol. F.C17H18N4OS
  • Mol. W.326.42 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 1
Olanzapine Impurity 1
  • CAT. No.O010033
  • CAS. No.873895-41-1
  • Mol. F.C12H11N3S
  • Mol. W.229.30 g/mol
  • Stock Status:Instock
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Olanzapine Impurity 2
Olanzapine Impurity 2
  • CAT. No.O010034
  • CAS. No.NA
  • Mol. F.C12H10N2OS
  • Mol. W.230.29 g/mol
  • Stock Status:Instock
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Olanzapine Impurity 3
Olanzapine Impurity 3
  • CAT. No.O010035
  • CAS. No.NA
  • Mol. F.C18H23N4S
  • Mol. W.402.40 g/mol
  • Stock Status:Custom Synthesis
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4-Fluoro Olanzapine
4-Fluoro Olanzapine
  • CAT. No.O010036
  • CAS. No.NA
  • Mol. F.C17H19FN4S
  • Mol. W.330.42 g/mol
  • Stock Status:Instock
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1,1-dimethyl-4-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazin-1-ium
1,1-dimethyl-4-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazin-1-ium
  • CAT. No.O010037
  • CAS. No.NA
  • Mol. F.C18H23N4S
  • Mol. W.327.47 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 4
Olanzapine Impurity 4
  • CAT. No.O010038
  • CAS. No.NA
  • Mol. F.C29H28N6S2
  • Mol. W.524.70 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 9
Olanzapine Impurity 9
  • CAT. No.O010039
  • CAS. No.NA
  • Mol. F.C18H16N4OS2
  • Mol. W.368.48 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine 10-N-glucuronide
Olanzapine 10-N-glucuronide
  • CAT. No.O010040
  • CAS. No.186792-80-3
  • Mol. F.C23H28N4O6S
  • Mol. W.488.56 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Olanzapine
N-Nitroso Olanzapine
  • CAT. No.O010041
  • CAS. No.NA
  • Mol. F.C17H19N5OS
  • Mol. W.341.43 g/mol
  • Stock Status:Under Synthesis
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2-methyl-10-nitroso-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine
2-methyl-10-nitroso-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine
  • CAT. No.O010042
  • CAS. No.NA
  • Mol. F.C12H10N4OS
  • Mol. W.258.30 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Nitroso Impurity 2
Olanzapine Nitroso Impurity 2
  • CAT. No.O010043
  • CAS. No.NA
  • Mol. F.C12H8N4O3S
  • Mol. W.288.28 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Nitroso Impurity 1
Olanzapine Nitroso Impurity 1
  • CAT. No.O010044
  • CAS. No.NA
  • Mol. F.C16H17N5OS
  • Mol. W.327.40 g/mol
  • Stock Status:Instock
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Olanzapine Ketothiolactam S-Oxide
Olanzapine Ketothiolactam S-Oxide
  • CAT. No.O010045
  • CAS. No.NA
  • Mol. F.C17H20N4O2S
  • Mol. W.344.43 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso N-Desmethyl Olanzapine
N-Nitroso N-Desmethyl Olanzapine
  • CAT. No.O010046
  • CAS. No.NA
  • Mol. F.C16H17N5OS
  • Mol. W.327.40 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Formyl Impurity
Olanzapine Formyl Impurity
  • CAT. No.O010048
  • CAS. No.NA
  • Mol. F.C18H20N4OS
  • Mol. W.340.44 g/mol
  • Stock Status:Instock
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Olanzapine open ring analog
Olanzapine open ring analog
  • CAT. No.O010049
  • CAS. No.1320360-86-8
  • Mol. F.C15H18N4OS
  • Mol. W.302.39 g/mol
  • Stock Status:Under Synthesis
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Olanzapine (Form-II)
Olanzapine (Form-II)
  • CAT. No.O010051
  • CAS. No.132539-06-1
  • Mol. F.C17H20N4S
  • Mol. W.312.43 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 5
Olanzapine Impurity 5
  • CAT. No.O010052
  • CAS. No.NA
  • Mol. F.C15H18N4OS
  • Mol. W.302.40 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine impurity 6
Olanzapine impurity 6
  • CAT. No.O010053
  • CAS. No.2554975-45-8
  • Mol. F.C17H14N4O2
  • Mol. W.306.32 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine Impurity 7
Olanzapine Impurity 7
  • CAT. No.O010055
  • CAS. No.NA
  • Mol. F.C24H20N6S2
  • Mol. W.456.59 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

2-Hydroxymethyl Olanzapine
2-Hydroxymethyl Olanzapine
  • CAT. No.O010047
  • CAS. No.174756-45-7
  • Mol. F.C17H20N4OS
  • Mol. W.328.43 g/mol
  • Stock Status:Custom Synthesis
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7-Hydroxy Olanzapine
7-Hydroxy Olanzapine
  • CAT. No.O010054
  • CAS. No.174686-64-7
  • Mol. F.C17H20N4OS
  • Mol. W.328.43 g/mol
  • Stock Status:Please Enquire
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Isotope Labelled Compounds

Olanzapine-d3
Olanzapine-d3
  • CAT. No.O010005
  • CAS. No.786686-79-1
  • Mol. F.C17H17N4SD3
  • Mol. W.315.46 g/mol
  • Stock Status:Instock
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Olanzapine-D8
Olanzapine-D8
  • CAT. No.O010021
  • CAS. No.1093380-13-2
  • Mol. F.C17H12D8N4S
  • Mol. W.320.48 g/mol
  • Stock Status:Custom Synthesis
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Olanzapine-D4
Olanzapine-D4
  • CAT. No.O010050
  • CAS. No.NA
  • Mol. F.C17H16D4N4S
  • Mol. W.316.46 g/mol
  • Stock Status:Custom Synthesis
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