Memantine Related Compounds & Impurities

Memantine is a moderate-affinity uncompetitive NMDA receptor antagonist used for moderate-to-severe Alzheimer's disease.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Memantine reference standards, pharmacopeial and non-pharmacopeial Memantine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Memantine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Memantine Hydrochloride
Memantine Hydrochloride
  • CAT. No.M110000
  • CAS. No.41100-52-1
  • Mol. F.C12H21N.HCl
  • Mol. W.215.76 g/mol
  • Stock Status:Instock
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Memantine
Memantine
  • CAT. No.M110000A
  • CAS. No.19982-08-2
  • Mol. F.C12H21N
  • Mol. W.179.30 g/mol
  • Stock Status:Instock
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Memantine Hydrochloride
Memantine Hydrochloride
  • CAT. No.M110000B
  • CAS. No.41100-52-1
  • Mol. F.C12H21N.HCl
  • Mol. W.215.76 g/mol
  • Stock Status:Under Synthesis
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Memantine Lactose Adduct (Free base)
Memantine Lactose Adduct (Free base)
  • CAT. No.M110002
  • CAS. No.1159637-28-1
  • Mol. F.C24H41NO10
  • Mol. W.503.58 g/mol
  • Stock Status:Custom Synthesis
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Memantine Lactose Adduct
Memantine Lactose Adduct
  • CAT. No.M110002A
  • CAS. No.1159637-28-1
  • Mol. F.C24H41NO10.H2O
  • Mol. W.521.60 g/mol
  • Stock Status:Instock
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Memantine Related Compound C
Memantine Related Compound C
  • CAT. No.M110003
  • CAS. No.707-36-8
  • Mol. F.C12H19Cl
  • Mol. W.198.73 g/mol
  • Stock Status:Instock
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Memantine Related Compound B
Memantine Related Compound B
  • CAT. No.M110004
  • CAS. No.707-37-9
  • Mol. F.C12H20O
  • Mol. W.180.29 g/mol
  • Stock Status:Instock
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1-Bromo-3,5-dimethyladamantane
1-Bromo-3,5-dimethyladamantane
  • CAT. No.M110005
  • CAS. No.941-37-7
  • Mol. F.C12H19Br
  • Mol. W.243.18 g/mol
  • Stock Status:Instock
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Acetyl Memantine
Acetyl Memantine
  • CAT. No.M110006
  • CAS. No.19982-07-1
  • Mol. F.C14H23NO
  • Mol. W.221.34 g/mol
  • Stock Status:Instock
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7-Hydroxy Memantine Impurity
7-Hydroxy Memantine Impurity
  • CAT. No.M110007
  • CAS. No.356572-08-2
  • Mol. F.C12H21NO.HCl
  • Mol. W.231.76 g/mol
  • Stock Status:Instock
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Memantine EP Impurity A Hydrochloride
Memantine EP Impurity A Hydrochloride
  • CAT. No.M110008
  • CAS. No.33103-93-4
  • Mol. F.C11H19N.HCl
  • Mol. W.201.74 g/mol
  • Stock Status:Instock
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Memantine EP Impurity A
Memantine EP Impurity A
  • CAT. No.M110008A
  • CAS. No.78056-28-7
  • Mol. F.C11H19N
  • Mol. W.165.28 g/mol
  • Stock Status:Custom Synthesis
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1-Bromo Adamantane
1-Bromo Adamantane
  • CAT. No.M110009
  • CAS. No.768-90-1
  • Mol. F.C10H15Br
  • Mol. W.215.13 g/mol
  • Stock Status:Instock
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1,3-Adamantanediol
1,3-Adamantanediol
  • CAT. No.M110010
  • CAS. No.5001-18-3
  • Mol. F.C10H16O2
  • Mol. W.168.20 g/mol
  • Stock Status:Instock
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1,3,5-Tribromoadamentane
1,3,5-Tribromoadamentane
  • CAT. No.M110011
  • CAS. No.707-34-6
  • Mol. F.C10H13Br3
  • Mol. W.372.92 g/mol
  • Stock Status:Instock
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1,3,5-Trimethyladamantane
1,3,5-Trimethyladamantane
  • CAT. No.M110012
  • CAS. No.707-35-7
  • Mol. F.C13H22
  • Mol. W.178.00 g/mol
  • Stock Status:Instock
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N-Formyl Memantine
N-Formyl Memantine
  • CAT. No.M110013
  • CAS. No.351329-88-9
  • Mol. F.C13H21NO
  • Mol. W.207.31 g/mol
  • Stock Status:Instock
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1-Methyl adamantane
1-Methyl adamantane
  • CAT. No.M110014
  • CAS. No.768-91-2
  • Mol. F.C11H18
  • Mol. W.150.26 g/mol
  • Stock Status:Instock
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Adamentane
Adamentane
  • CAT. No.M110015
  • CAS. No.281-23-2
  • Mol. F.C10H16
  • Mol. W.136.23 g/mol
  • Stock Status:Instock
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1 Amino-3 Hydroxy Adamantane
1 Amino-3 Hydroxy Adamantane
  • CAT. No.M110016
  • CAS. No.702-82-9
  • Mol. F.C10H17NO
  • Mol. W.167.25 g/mol
  • Stock Status:Instock
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3-Amino-1-adamantanol hydrochloride
3-Amino-1-adamantanol hydrochloride
  • CAT. No.M110016A
  • CAS. No.NA
  • Mol. F.C10H17NO.HCl
  • Mol. W.203.71 g/mol
  • Stock Status:Instock
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Memantine Related Compound A
Memantine Related Compound A
  • CAT. No.M110017
  • CAS. No.702-79-4
  • Mol. F.C12H2O
  • Mol. W.164.29 g/mol
  • Stock Status:Instock
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1-ethyladamantane 
1-ethyladamantane 
  • CAT. No.M110018
  • CAS. No.770-69-4 
  • Mol. F.C12H20
  • Mol. W.164.29 g/mol
  • Stock Status:Instock
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1-Nitroadamantane
1-Nitroadamantane
  • CAT. No.M110019
  • CAS. No.7575-82-8
  • Mol. F.CHNO
  • Mol. W.181.23 g/mol
  • Stock Status:Under Synthesis
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Memantine EP Impurity E
Memantine EP Impurity E
  • CAT. No.M110020
  • CAS. No.6588-68-7
  • Mol. F.C12H19NO2
  • Mol. W.209.29 g/mol
  • Stock Status:Custom Synthesis
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1,4-Dimethyl Adamantane
1,4-Dimethyl Adamantane
  • CAT. No.M110023
  • CAS. No.16267-35-9
  • Mol. F.C12H20
  • Mol. W.164.29 g/mol
  • Stock Status:Instock
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Memantine EP Impurity D Hydrochloride
Memantine EP Impurity D Hydrochloride
  • CAT. No.M110024
  • CAS. No.80121-67-1
  • Mol. F.C12H21N.HCl
  • Mol. W.215.76 g/mol
  • Stock Status:Instock
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Memantine EP Impurity B Hydrochloride
Memantine EP Impurity B Hydrochloride
  • CAT. No.M110025
  • CAS. No.15210-60-3
  • Mol. F.C13H23N.HCl
  • Mol. W.229.79 g/mol
  • Stock Status:Instock
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N-Acetyl Demethyl Memantine
N-Acetyl Demethyl Memantine
  • CAT. No.M110029
  • CAS. No.778-09-6
  • Mol. F.C13H21NO
  • Mol. W.207.31 g/mol
  • Stock Status:Custom Synthesis
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Adamantane Impurity 2
Adamantane Impurity 2
  • CAT. No.M110030
  • CAS. No.702-77-2
  • Mol. F.C11H17Br
  • Mol. W.229.16 g/mol
  • Stock Status:Custom Synthesis
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3-(Hydroxymethyl)-1-adamantol
3-(Hydroxymethyl)-1-adamantol
  • CAT. No.M110031
  • CAS. No.38584-37-1
  • Mol. F.C11H18O2
  • Mol. W.182.26 g/mol
  • Stock Status:Instock
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Adamantane Impurity 1
Adamantane Impurity 1
  • CAT. No.M110032
  • CAS. No.53398-55-3
  • Mol. F.C13H21Br
  • Mol. W.257.21 g/mol
  • Stock Status:Instock
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7-Hydroxy Memantine Hydrochloride
7-Hydroxy Memantine Hydrochloride
  • CAT. No.M110033
  • CAS. No.356572-08-2
  • Mol. F.C12H22ClNO
  • Mol. W.231.76 g/mol
  • Stock Status:Instock
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1-Amino-3-hydroxy-5,7-dimethyladamantane hydrate
1-Amino-3-hydroxy-5,7-dimethyladamantane hydrate
  • CAT. No.M110033A
  • CAS. No.NA
  • Mol. F.C12H23NO2
  • Mol. W.213.32 g/mol
  • Stock Status:Instock
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1-Hydroxy-3-amino-5,7-dimethyladamantane
1-Hydroxy-3-amino-5,7-dimethyladamantane
  • CAT. No.M110033B
  • CAS. No.63971-25-5
  • Mol. F.C12H21NO
  • Mol. W.195.30 g/mol
  • Stock Status:Instock
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Adamantane Impurity 5
Adamantane Impurity 5
  • CAT. No.M110034
  • CAS. No.15210-64-7
  • Mol. F.C15H25NO
  • Mol. W.235.37 g/mol
  • Stock Status:Custom Synthesis
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Amantadine Sulfate
Amantadine Sulfate
  • CAT. No.M110035
  • CAS. No.31377-23-8
  • Mol. F.C20H36N2O4S
  • Mol. W.400.58 g/mol
  • Stock Status:Custom Synthesis
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(S)-Boc-adamantylglycine
(S)-Boc-adamantylglycine
  • CAT. No.M110038
  • CAS. No.361441-97-6
  • Mol. F.C17H27NO4
  • Mol. W.309.40 g/mol
  • Stock Status:Custom Synthesis
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5,7-Dimethyladamantane-1,3-diamine
5,7-Dimethyladamantane-1,3-diamine
  • CAT. No.M110039
  • CAS. No.19385-96-7
  • Mol. F.C12H22N2
  • Mol. W.194.32 g/mol
  • Stock Status:Custom Synthesis
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Amantadine Impurity 3
Amantadine Impurity 3
  • CAT. No.M110040
  • CAS. No.878-61-5
  • Mol. F.C12H19Br
  • Mol. W.243.18 g/mol
  • Stock Status:Custom Synthesis
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Memantine Amide Impurity
Memantine Amide Impurity
  • CAT. No.M110041
  • CAS. No.NA
  • Mol. F.C14H24N2O
  • Mol. W.236.35 g/mol
  • Stock Status:Custom Synthesis
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Adamantane-3
Adamantane-3
  • CAT. No.M110042
  • CAS. No.2460757-92-8
  • Mol. F.C12H19NO3
  • Mol. W.225.29 g/mol
  • Stock Status:Custom Synthesis
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1,3,5,7-Tetrabromoadamantane
1,3,5,7-Tetrabromoadamantane
  • CAT. No.M110043
  • CAS. No.7314-86-5
  • Mol. F.C10H12Br4
  • Mol. W.451.82 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Memantine
N-Nitroso Memantine
  • CAT. No.M110044
  • CAS. No.NA
  • Mol. F.C12H20N2O
  • Mol. W.208.30 g/mol
  • Stock Status:Custom Synthesis
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Memantine Dimer Hydrochloride
Memantine Dimer Hydrochloride
  • CAT. No.M110046
  • CAS. No.802293-70-5 (free base)
  • Mol. F.C24H39N.HCl
  • Mol. W.378.03 g/mol
  • Stock Status:Instock
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Memantine Impurity 1
Memantine Impurity 1
  • CAT. No.M110047
  • CAS. No.1082700-69-3
  • Mol. F.C23H38N2
  • Mol. W.342.56 g/mol
  • Stock Status:Custom Synthesis
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Memantine-Glucose Adduct
Memantine-Glucose Adduct
  • CAT. No.M110048
  • CAS. No.NA
  • Mol. F.C18H31NO5
  • Mol. W.341.44 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 2
Memantine Impurity 2
  • CAT. No.M110049
  • CAS. No.NA
  • Mol. F.C12H21NO
  • Mol. W.195.30 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 3
Memantine Impurity 3
  • CAT. No.M110050
  • CAS. No.NA
  • Mol. F.C13H23N
  • Mol. W.193.33 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 4
Memantine Impurity 4
  • CAT. No.M110051
  • CAS. No.NA
  • Mol. F.C12H21N
  • Mol. W.179.30 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 5
Memantine Impurity 5
  • CAT. No.M110052
  • CAS. No.20098-19-5
  • Mol. F.C10H17NO.HCl
  • Mol. W.203.71 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 6
Memantine Impurity 6
  • CAT. No.M110053
  • CAS. No.16207-81-1
  • Mol. F.C12H20
  • Mol. W.164.29 g/mol
  • Stock Status:Custom Synthesis
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Memantine Impurity 7
Memantine Impurity 7
  • CAT. No.M110054
  • CAS. No.14451-87-7
  • Mol. F.C12H20
  • Mol. W.164.29 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Memantine N-Beta-D-Glucuronide
Memantine N-Beta-D-Glucuronide
  • CAT. No.M110026
  • CAS. No.1809031-06-8
  • Mol. F.C18H29NO6
  • Mol. W.355.43 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Memantine-D6 Hydrochloride
Memantine-D6 Hydrochloride
  • CAT. No.M110021
  • CAS. No.1189713-18-5
  • Mol. F.C12H16D6ClN
  • Mol. W.221.80 g/mol
  • Stock Status:Instock
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Memantine-D3 Hydrochloride
Memantine-D3 Hydrochloride
  • CAT. No.M110022
  • CAS. No.NA
  • Mol. F.C12H16D6ClN
  • Mol. W.221.80 g/mol
  • Stock Status:Custom Synthesis
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[13C2 ,D6]-Memantine hydrochloride
[13C2 ,D6]-Memantine hydrochloride
  • CAT. No.M110045
  • CAS. No.NA
  • Mol. F.C1013C2H16D6ClN
  • Mol. W.223.79 g/mol
  • Stock Status:Custom Synthesis
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