Levosimendan Related Compounds & Impurities

Levosimendan is a calcium sensitiser inodilator that enhances cardiac contractility without increasing oxygen demand, used for acute decompensated heart failure.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Levosimendan reference standards, pharmacopeial and non-pharmacopeial Levosimendan impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Levosimendan-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Levosimendan
Levosimendan
  • CAT. No.L590000
  • CAS. No.141505-33-1
  • Mol. F.C14H12N6O
  • Mol. W.280.29 g/mol
  • Stock Status:Instock
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Rac-Levosimendan
Rac-Levosimendan
  • CAT. No.L590000A
  • CAS. No.131741-08-7
  • Mol. F.C14H12N6O
  • Mol. W.280.28 g/mol
  • Stock Status:Instock
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Levosimendan Impurity 10
Levosimendan Impurity 10
  • CAT. No.L590001
  • CAS. No.252638-01-0
  • Mol. F.C14H11N7O2
  • Mol. W.309.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Cyanoacetamide Hydrazone Impurity
Levosimendan Cyanoacetamide Hydrazone Impurity
  • CAT. No.L590006
  • CAS. No.274263-65-9
  • Mol. F.C14H14N6O2
  • Mol. W.298.31 g/mol
  • Stock Status:Instock
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Levosimendan Impurity 6
Levosimendan Impurity 6
  • CAT. No.L590007
  • CAS. No.36725-28-7
  • Mol. F.C11H13N3O
  • Mol. W.203.25 g/mol
  • Stock Status:Instock
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(S)-5-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one
(S)-5-methyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one
  • CAT. No.L590010
  • CAS. No.NA
  • Mol. F.C11H12N2O
  • Mol. W.188.23 g/mol
  • Stock Status:Custom Synthesis
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Dextrosimendan
Dextrosimendan
  • CAT. No.L590011
  • CAS. No.144238-75-5
  • Mol. F.C14H12N6O
  • Mol. W.280.28 g/mol
  • Stock Status:Instock
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Evosimendan Dimer Impurity
Evosimendan Dimer Impurity
  • CAT. No.L590013
  • CAS. No.618458-79-0
  • Mol. F.C30H30N12O3
  • Mol. W.606.64 g/mol
  • Stock Status:Custom Synthesis
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(R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
(R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
  • CAT. No.L590014
  • CAS. No.101328-85-2
  • Mol. F.C11H13N3O
  • Mol. W.203.2 g/mol
  • Stock Status:Custom Synthesis
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(S)-5-methyl-6-(p-tolyl)-4,5-dihydropyridazin-3(2H)-one
(S)-5-methyl-6-(p-tolyl)-4,5-dihydropyridazin-3(2H)-one
  • CAT. No.L590015
  • CAS. No.NA
  • Mol. F.C12H14N2O
  • Mol. W.202.25 g/mol
  • Stock Status:Custom Synthesis
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(S)-6-(4-(2-(diisocyanomethylene)hydrazinyl)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
(S)-6-(4-(2-(diisocyanomethylene)hydrazinyl)phenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one
  • CAT. No.L590016
  • CAS. No.NA
  • Mol. F.C14H12N6O
  • Mol. W.280.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Related Compound C
Levosimendan Related Compound C
  • CAT. No.L590017
  • CAS. No.NA
  • Mol. F.C22H23N7O2
  • Mol. W.417.46 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Related Compound E
Levosimendan Related Compound E
  • CAT. No.L590018
  • CAS. No.NA
  • Mol. F.C14H14N4O4
  • Mol. W.302.29 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Related Compound F
Levosimendan Related Compound F
  • CAT. No.L590019
  • CAS. No.NA
  • Mol. F.C14H12N4O3
  • Mol. W.284.27 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Cyanoacetate Hydrazone Impurity
Levosimendan Cyanoacetate Hydrazone Impurity
  • CAT. No.L590020
  • CAS. No.NA
  • Mol. F.C16H17N5O3
  • Mol. W.327.34 g/mol
  • Stock Status:Instock
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Levosimendan Nitroso Impurity
Levosimendan Nitroso Impurity
  • CAT. No.L590021
  • CAS. No.NA
  • Mol. F.C14H11N7O2
  • Mol. W.309.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 50
Levosimendan Impurity 50
  • CAT. No.L590022
  • CAS. No.36568-05-5
  • Mol. F.C3HN3O
  • Mol. W.95.06 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levosimendan Impurity 49
N-Nitroso Levosimendan Impurity 49
  • CAT. No.L590023
  • CAS. No.NA
  • Mol. F.C11H12N4O2
  • Mol. W.232.24 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 20
Levosimendan Impurity 20
  • CAT. No.L590024
  • CAS. No.81937-39-5
  • Mol. F.C18H23NO6
  • Mol. W.349.38 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 21
Levosimendan Impurity 21
  • CAT. No.L590025
  • CAS. No.NA
  • Mol. F.C15H15N5O3
  • Mol. W.313.31 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 3
Levosimendan Impurity 3
  • CAT. No.L590026
  • CAS. No.2493974-39-1
  • Mol. F.C14H14N6O2
  • Mol. W.298.30 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 18
Levosimendan Impurity 18
  • CAT. No.L590027
  • CAS. No.NA
  • Mol. F.C15H15N5O3
  • Mol. W.313.31 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 19
Levosimendan Impurity 19
  • CAT. No.L590028
  • CAS. No.81112-08-5
  • Mol. F.C11H12ClNO2
  • Mol. W.225.67 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 51
Levosimendan Impurity 51
  • CAT. No.L590029
  • CAS. No.NA
  • Mol. F.C14H11N7O2
  • Mol. W.309.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 11
Levosimendan Impurity 11
  • CAT. No.L590030
  • CAS. No.NA
  • Mol. F.C14H14N6O2
  • Mol. W.298.30 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 52
Levosimendan Impurity 52
  • CAT. No.L590031
  • CAS. No.1643439-59-1
  • Mol. F.C22H23N7O2
  • Mol. W.417.46 g/mol
  • Stock Status:Instock
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Levosimendan Impurity 7
Levosimendan Impurity 7
  • CAT. No.L590032
  • CAS. No.NA
  • Mol. F.C14H14N6O2
  • Mol. W.298.30 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 8
Levosimendan Impurity 8
  • CAT. No.L590033
  • CAS. No.NA
  • Mol. F.C30H30N12O3
  • Mol. W.606.64 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 9
Levosimendan Impurity 9
  • CAT. No.L590034
  • CAS. No.NA
  • Mol. F.C14H11N7O2
  • Mol. W.309.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 12
Levosimendan Impurity 12
  • CAT. No.L590035
  • CAS. No.NA
  • Mol. F.C28H24N12O2
  • Mol. W.560.57 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 13
Levosimendan Impurity 13
  • CAT. No.L590036
  • CAS. No.NA
  • Mol. F.C14H11N7O2
  • Mol. W.309.28 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 14
Levosimendan Impurity 14
  • CAT. No.L590037
  • CAS. No.NA
  • Mol. F.C14H10N6O
  • Mol. W.278.27 g/mol
  • Stock Status:Custom Synthesis
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Levosimendan Impurity 5
Levosimendan Impurity 5
  • CAT. No.L590038
  • CAS. No.NA
  • Mol. F.C14H14N6O2
  • Mol. W.298.30 g/mol
  • Stock Status:Custom Synthesis
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