Levofloxacin Related Compounds & Impurities

Levofloxacin is the L-enantiomer of ofloxacin, a broad-spectrum fluoroquinolone antibiotic used for respiratory, urinary and soft tissue infections.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Levofloxacin reference standards, pharmacopeial and non-pharmacopeial Levofloxacin impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Levofloxacin-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Levofloxacin Hemihydrate
Levofloxacin Hemihydrate
  • CAT. No.L050000
  • CAS. No.138199-71-0
  • Mol. F.C18H20FN3O4 .1/2 H2O
  • Mol. W.740.75 g/mol
  • Stock Status:Instock
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Levofloxacin
Levofloxacin
  • CAT. No.L050000A
  • CAS. No.100986-85-4
  • Mol. F.C18H20FN3O4
  • Mol. W.361.37 g/mol
  • Stock Status:Instock
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Levofloxacin EP Impurity B
Levofloxacin EP Impurity B
  • CAT. No.L050001
  • CAS. No.117707-40-1
  • Mol. F.C17H18FN3O4
  • Mol. W.347.34 g/mol
  • Stock Status:Instock
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Levofloxacin N-Oxide
Levofloxacin N-Oxide
  • CAT. No.L050002
  • CAS. No.117678-38-3
  • Mol. F.C18H20FN3O5
  • Mol. W.377.37 g/mol
  • Stock Status:Instock
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Levofloxacin N-Oxide
Levofloxacin N-Oxide
  • CAT. No.L050002A
  • CAS. No.117678-37-2
  • Mol. F.C18H20FN3O5
  • Mol. W.377.37 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin 9-Piperazine Isomer
Levofloxacin 9-Piperazine Isomer
  • CAT. No.L050003
  • CAS. No.178912-62-4
  • Mol. F.C18H20FN3O4
  • Mol. W.361.37 g/mol
  • Stock Status:Instock
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Levofloxacin Diamine Impurity Hydrochloride
Levofloxacin Diamine Impurity Hydrochloride
  • CAT. No.L050004
  • CAS. No.1797099-76-3
  • Mol. F.C15H16FN3O4.HCl
  • Mol. W.357.76 g/mol
  • Stock Status:Instock
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Levofloxacin Diamine Hydrochloride
Levofloxacin Diamine Hydrochloride
  • CAT. No.L050004A
  • CAS. No.1797099-76-3
  • Mol. F.C15H16FN3O4.HCl
  • Mol. W.357.76 g/mol
  • Stock Status:Instock
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Levofloxacin EP Impurity D
Levofloxacin EP Impurity D
  • CAT. No.L050005
  • CAS. No.117620-85-6
  • Mol. F.C18H21N3O4
  • Mol. W.343.38 g/mol
  • Stock Status:Instock
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Descarboxyl Levofloxacin Impurity Hydrochloride
Descarboxyl Levofloxacin Impurity Hydrochloride
  • CAT. No.L050006
  • CAS. No.178964-53-9(FreeBase)
  • Mol. F.C17H20FN3O2.HCl
  • Mol. W.353.8 g/mol; 317.2 g/mol (Free Base)
  • Stock Status:Instock
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Descarboxyl Levofloxacin Impurity
Descarboxyl Levofloxacin Impurity
  • CAT. No.L050006A
  • CAS. No.178964-53-9
  • Mol. F.C17H20FN3O2
  • Mol. W.317.36 g/mol
  • Stock Status:Instock
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Levofloxacin EP Impurity F
Levofloxacin EP Impurity F
  • CAT. No.L050007
  • CAS. No.100986-89-8
  • Mol. F.C13H9F2NO4
  • Mol. W.281.21 g/mol
  • Stock Status:Instock
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Ofloxacin R-Isomer
Ofloxacin R-Isomer
  • CAT. No.L050008
  • CAS. No.100986-86-5
  • Mol. F.C18H20FN3O4
  • Mol. W.361.37 g/mol
  • Stock Status:Instock
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Levofloxacin Hemihydrate
Levofloxacin Hemihydrate
  • CAT. No.L050008A
  • CAS. No.NA
  • Mol. F.C18H20FN3O4.1/2H2O
  • Mol. W.370.38 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Hydrochloride
Levofloxacin Hydrochloride
  • CAT. No.L050009
  • CAS. No.177325-13-2;100986-85-4(Freebase)
  • Mol. F.C18H20FN3O4.HCl
  • Mol. W.397.83 g/mol
  • Stock Status:Under Synthesis
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Levofloxacin EP Impurity G Hydrochloride salt
Levofloxacin EP Impurity G Hydrochloride salt
  • CAT. No.L050010
  • CAS. No.1346603-62-0
  • Mol. F.C16H19FN3O4Cl
  • Mol. W.371.79 g/mol
  • Stock Status:Instock
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Levofloxacin EP Impurity I
Levofloxacin EP Impurity I
  • CAT. No.L050011
  • CAS. No.178912-62-4
  • Mol. F.C18H20FN3O4
  • Mol. W.377.41 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Related Compound C
Levofloxacin Related Compound C
  • CAT. No.L050012
  • CAS. No. 177472-30-9
  • Mol. F.C20H24FN3O4
  • Mol. W.389.42 g/mol
  • Stock Status:Instock
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D-Alaninol
D-Alaninol
  • CAT. No.L050014
  • CAS. No.35320-23-1
  • Mol. F.C3H9NO
  • Mol. W.75.11 g/mol
  • Stock Status:Instock
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Levofloxacin Impurity 2
Levofloxacin Impurity 2
  • CAT. No.L050015
  • CAS. No.NA
  • Mol. F.C9H11F2NO5S
  • Mol. W.283.25 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 3
Levofloxacin Impurity 3
  • CAT. No.L050016
  • CAS. No.NA
  • Mol. F.C10H12F2N2O3S
  • Mol. W.278.28 g/mol
  • Stock Status:Custom Synthesis
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Ethyl 2-(2,3,4,5-Tetrafluorobenzoyl)acetate
Ethyl 2-(2,3,4,5-Tetrafluorobenzoyl)acetate
  • CAT. No.L050017
  • CAS. No.94695-50-8
  • Mol. F.C11H8F4O3
  • Mol. W.264.18 g/ mol
  • Stock Status:Instock
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Ethyl 3-(N,N-dimethylamino)-2-(2,3,4,5-Tetrafluorobenzoyl)acrylate
Ethyl 3-(N,N-dimethylamino)-2-(2,3,4,5-Tetrafluorobenzoyl)acrylate
  • CAT. No.L050018
  • CAS. No.138998-47-7
  • Mol. F.C14H13F4NO3
  • Mol. W.319.25 g/mol
  • Stock Status:Custom Synthesis
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Ethyl (2Z)-3-1-hydroxy-2-propanyl)amino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate
Ethyl (2Z)-3-1-hydroxy-2-propanyl)amino)-2-(2,3,4,5-tetrafluorobenzoyl)acrylate
  • CAT. No.L050019
  • CAS. No.110548-02-2
  • Mol. F.C15H15F4NO4
  • Mol. W.349.28 g/mol
  • Stock Status:Custom Synthesis
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(3S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
(3S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
  • CAT. No.L050020
  • CAS. No.117620-84-5
  • Mol. F.C13H10FNO4
  • Mol. W.263.22 g/mol
  • Stock Status:Custom Synthesis
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(R)-Ofloxacin Carboxylic Acid
(R)-Ofloxacin Carboxylic Acid
  • CAT. No.L050021
  • CAS. No.110548-07-7
  • Mol. F.C13H9F2NO4
  • Mol. W.281.21 g/mol
  • Stock Status:Instock
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Levofloxacin Isomer Ester Impurity
Levofloxacin Isomer Ester Impurity
  • CAT. No.L050022
  • CAS. No.NA
  • Mol. F.C20H24FN3O4
  • Mol. W.389.42 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Chloromethyl Ester
Levofloxacin Chloromethyl Ester
  • CAT. No.L050023
  • CAS. No.2206825-95-6
  • Mol. F.C19H21ClFN3O4
  • Mol. W.409.84 g/mol
  • Stock Status:Custom Synthesis
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N-Ethyl Levofloxacin
N-Ethyl Levofloxacin
  • CAT. No.L050024
  • CAS. No.106939-30-4
  • Mol. F.C19H22FN3O4
  • Mol. W.375.39 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Piperacinylbenzoxazole
Levofloxacin Piperacinylbenzoxazole
  • CAT. No.L050025
  • CAS. No.885517-47-5
  • Mol. F.C19H22FN3O4
  • Mol. W.375.39 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Methyl Ester
Levofloxacin Methyl Ester
  • CAT. No.L050026
  • CAS. No.862690-19-5
  • Mol. F.C19H22FN3O4
  • Mol. W.375.39 g/mol
  • Stock Status:Instock
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Levofloxacin EP Impurity H
Levofloxacin EP Impurity H
  • CAT. No.L050027
  • CAS. No.177472-30-9
  • Mol. F.C20H24FN3O4
  • Mol. W.389.40 g/mol
  • Stock Status:Instock
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(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-chloromethyl-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-chloromethyl-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylate
  • CAT. No.L050028
  • CAS. No.NA
  • Mol. F.C19H21ClFN3O4
  • Mol. W.409.84 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin EP impurity I Hydrochloride
Levofloxacin EP impurity I Hydrochloride
  • CAT. No.L050029
  • CAS. No.NA
  • Mol. F.C18H21ClFN3O4.HCl
  • Mol. W.397.83 g/mol
  • Stock Status:Custom Synthesis
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(S)-7,8-difluoro-3-methyl-2,3-dihydrobenzo[1,4]oxazine hydrogen sulfate
(S)-7,8-difluoro-3-methyl-2,3-dihydrobenzo[1,4]oxazine hydrogen sulfate
  • CAT. No.L050030
  • CAS. No.NA
  • Mol. F.C9H11F2NO5S
  • Mol. W.283.25 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 9
Levofloxacin Impurity 9
  • CAT. No.L050031
  • CAS. No.1329833-82-0
  • Mol. F.C23H31N5O4
  • Mol. W.441.52 g/mol
  • Stock Status:Custom Synthesis
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9-Chloro-9-defluoro Ofloxacin
9-Chloro-9-defluoro Ofloxacin
  • CAT. No.L050032
  • CAS. No.82419-45-2
  • Mol. F.C18H20ClN3O4
  • Mol. W.377.82 g/mol
  • Stock Status:Instock
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Levofloxacin Impurity 7
Levofloxacin Impurity 7
  • CAT. No.L050033
  • CAS. No.1430222-73-3
  • Mol. F.C16H18FN3O2
  • Mol. W.303.33 g/mol
  • Stock Status:Instock
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Levofloxacin Impurity 8
Levofloxacin Impurity 8
  • CAT. No.L050034
  • CAS. No.151250-74-7
  • Mol. F.C13H11FN2O4
  • Mol. W.278.24 g/mol
  • Stock Status:Instock
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Desmethyl Levofloxacin
Desmethyl Levofloxacin
  • CAT. No.L050035
  • CAS. No.117707-40-1
  • Mol. F.C17H18FN3O4
  • Mol. W.347.34 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Desethylene Diformyl Impurity
Levofloxacin Desethylene Diformyl Impurity
  • CAT. No.L050036
  • CAS. No.151377-74-1
  • Mol. F.C18H18FN3O6
  • Mol. W.391.35 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levofloxacin
N-Nitroso Levofloxacin
  • CAT. No.L050037
  • CAS. No.1152314-62-9
  • Mol. F.C17H17FN4O5
  • Mol. W.376.30 g/mol
  • Stock Status:Instock
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Levofloxacin Hemihydrate EP Impurty G
Levofloxacin Hemihydrate EP Impurty G
  • CAT. No.L050038
  • CAS. No.151250-76-9
  • Mol. F.C16H18FN3O4
  • Mol. W.335.33 g/mol
  • Stock Status:Instock
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Levofloxacin Diamine Impurity
Levofloxacin Diamine Impurity
  • CAT. No.L050039
  • CAS. No.1797510-34-9
  • Mol. F.C15H16FN3O4
  • Mol. W.321.30 g/mol
  • Stock Status:Under Synthesis
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9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin hydrochloride
9-Defluoro-9-(4-methyl-1-piperazinyl) Levofloxacin hydrochloride
  • CAT. No.L050040
  • CAS. No.NA
  • Mol. F.C23H32ClN5O4
  • Mol. W.477.98 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levofloxacin Impurity 3
N-Nitroso Levofloxacin Impurity 3
  • CAT. No.L050041
  • CAS. No.NA
  • Mol. F.C15H14F4N2O5
  • Mol. W.378.28 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levofloxacin Impurity 2
N-Nitroso Levofloxacin Impurity 2
  • CAT. No.L050042
  • CAS. No.NA
  • Mol. F.C15H16ClFN4O5
  • Mol. W.386.76 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levofloxacin Impurity 5
N-Nitroso Levofloxacin Impurity 5
  • CAT. No.L050043
  • CAS. No.NA
  • Mol. F.C15H15FN4O5
  • Mol. W.350.30 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Levofloxacin Impurity 4
N-Nitroso Levofloxacin Impurity 4
  • CAT. No.L050044
  • CAS. No.NA
  • Mol. F.C15H14FN3O5b
  • Mol. W.335.29 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Ofloxacin EP Impurity E
N-Nitroso Ofloxacin EP Impurity E
  • CAT. No.L050045
  • CAS. No.NA
  • Mol. F.C17H17FN4O5
  • Mol. W.376.30 g/mol
  • Stock Status:Instock
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Levofloxacin Impurity 11
Levofloxacin Impurity 11
  • CAT. No.L050046
  • CAS. No.889110-57-0
  • Mol. F.C14H11F2NO4
  • Mol. W.295.24 g/mol
  • Stock Status:Custom Synthesis
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N-Dinitroso Levofloxacin EP Impurity G
N-Dinitroso Levofloxacin EP Impurity G
  • CAT. No.L050047
  • CAS. No.NA
  • Mol. F.C16H16FN5O6
  • Mol. W.393.33 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin EP Impurity H
Levofloxacin EP Impurity H
  • CAT. No.L050048
  • CAS. No.2489671-30-7
  • Mol. F.C20H24FN3O4
  • Mol. W.389.42 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 6
Levofloxacin Impurity 6
  • CAT. No.L050049
  • CAS. No.82419-34-9
  • Mol. F.C15H13F2NO4
  • Mol. W.309.27 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 1
Levofloxacin Impurity 1
  • CAT. No.L050050
  • CAS. No.1363407-28-6
  • Mol. F.C15H16F3NO4
  • Mol. W.331.29 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 9 Trifluoroacetic Acid
Levofloxacin Impurity 9 Trifluoroacetic Acid
  • CAT. No.L050051
  • CAS. No.NA
  • Mol. F.C23H31N5O4.C2HF3O2
  • Mol. W.555.55 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Hydroxy Acid
Levofloxacin Hydroxy Acid
  • CAT. No.L050052
  • CAS. No.1036016-10-0
  • Mol. F.C18H21F2N3O4
  • Mol. W.381.37 g/mol
  • Stock Status:Custom Synthesis
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Levofloxacin Impurity 10
Levofloxacin Impurity 10
  • CAT. No.L050053
  • CAS. No.110548-06-6
  • Mol. F.C15H13F2NO4
  • Mol. W.309.30 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Levofloxacin D8
Levofloxacin D8
  • CAT. No.L050013
  • CAS. No.1217716-71-6
  • Mol. F.C18H12D8FN3O4
  • Mol. W.369.42 g/mol
  • Stock Status:Limited Stock
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