Lenvatinib Related Compounds & Impurities

Lenvatinib is a multi-kinase inhibitor targeting VEGFR, FGFR, PDGFR and RET, used for thyroid, hepatocellular and endometrial cancers.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Lenvatinib reference standards, pharmacopeial and non-pharmacopeial Lenvatinib impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Lenvatinib-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Lenvatinib
Lenvatinib
  • CAT. No.L840000
  • CAS. No.417716-92-8
  • Mol. F.C21H19ClN4O4
  • Mol. W.426.85 g/mol
  • Stock Status:Instock
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Lenvatinib mesylate
Lenvatinib mesylate
  • CAT. No.L840000A
  • CAS. No.857890-39-2
  • Mol. F.C22H23ClN4O7S
  • Mol. W.522.96 g/mol
  • Stock Status:Instock
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Lenvatinib N-Oxide
Lenvatinib N-Oxide
  • CAT. No.L840001
  • CAS. No.1788901-86-9
  • Mol. F.C21H19ClN4O5
  • Mol. W.442.85 g/mol
  • Stock Status:Instock
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Desamino Hydroxy Lenvatinib
Desamino Hydroxy Lenvatinib
  • CAT. No.L840002
  • CAS. No.417717-21-6
  • Mol. F.C21H18ClN3O5
  • Mol. W.427.84 g/mol
  • Stock Status:Instock
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4-Amino-2,3,6-Trichlorophenol
4-Amino-2,3,6-Trichlorophenol
  • CAT. No.L840003
  • CAS. No.64981-10-8
  • Mol. F.C6H3Cl4NO
  • Mol. W.212.45 g/mol
  • Stock Status:Custom Synthesis
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O-Desmethyl Lenvatinib
O-Desmethyl Lenvatinib
  • CAT. No.L840005
  • CAS. No.417717-04-5
  • Mol. F.C20H17ClN4O4
  • Mol. W.412.83 g/mol
  • Stock Status:Instock
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Descyclopropyl Lenvatinib
Descyclopropyl Lenvatinib
  • CAT. No.L840006
  • CAS. No.417719-51-8
  • Mol. F.C18H15ClN4O4
  • Mol. W.386.80 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity O
Lenvatinib Impurity O
  • CAT. No.L840007
  • CAS. No.2143930-76-9
  • Mol. F.C20H19ClN4O4
  • Mol. W.414.84 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 16
Lenvatinib Impurity 16
  • CAT. No.L840008
  • CAS. No.1882873-21-3
  • Mol. F.C21H17ClN4O3
  • Mol. W.408.84 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 13
Lenvatinib Impurity 13
  • CAT. No.L840009
  • CAS. No.417722-93-1
  • Mol. F.C17H14ClN3O3
  • Mol. W.343.76 g/mol
  • Stock Status:Limited Stock
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Lenvatinib Impurity 8
Lenvatinib Impurity 8
  • CAT. No.L840010
  • CAS. No.417721-36-9
  • Mol. F.C11H9ClN2O2
  • Mol. W.236.66 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 14
Lenvatinib Impurity 14
  • CAT. No.L840015
  • CAS. No.417722-95-3
  • Mol. F.C24H18ClN3O5
  • Mol. W.463.87 g/mol
  • Stock Status:Instock
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Lenvatinib Mesylate Hydroxyl Amide Impurity
Lenvatinib Mesylate Hydroxyl Amide Impurity
  • CAT. No.L840016
  • CAS. No.2110414-05-4
  • Mol. F.C11H10N2O3
  • Mol. W.218.21 g/mol
  • Stock Status:Instock
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Lenvatinib Mesylate Cyclopropyl urea impurity
Lenvatinib Mesylate Cyclopropyl urea impurity
  • CAT. No.L840017
  • CAS. No.796848-79-8
  • Mol. F.C10H11ClN2O2
  • Mol. W.226.66 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 21
Lenvatinib Impurity 21
  • CAT. No.L840018
  • CAS. No.2023826-82-4
  • Mol. F.C12H11NO4
  • Mol. W.233.20 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 6
Lenvatinib Impurity 6
  • CAT. No.L840019
  • CAS. No.205448-66-4
  • Mol. F.C12H10ClNO3
  • Mol. W.251.67 g/mol
  • Stock Status:Custom Synthesis
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Descyclopropyl impurity
Descyclopropyl impurity
  • CAT. No.L840020
  • CAS. No.NA
  • Mol. F.C18H15ClN4O4
  • Mol. W.386.79 g/mol
  • Stock Status:Custom Synthesis
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N-Methyl Lenvatinib
N-Methyl Lenvatinib
  • CAT. No.L840021
  • CAS. No.417719-45-0
  • Mol. F.C19H17ClN4O4
  • Mol. W.400.82 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Mesylate (Form C)
Lenvatinib Mesylate (Form C)
  • CAT. No.L840022
  • CAS. No.NA
  • Mol. F.C22H23ClN4O7S
  • Mol. W.522.96 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 15
Lenvatinib Impurity 15
  • CAT. No.L840023
  • CAS. No.2023826-16-4
  • Mol. F.C17H12ClN3O2
  • Mol. W.325.75 g/mol
  • Stock Status:Custom Synthesis
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4-Ethoxy-7-methoxyquinoline-6-carboxamide
4-Ethoxy-7-methoxyquinoline-6-carboxamide
  • CAT. No.L840024
  • CAS. No.2143930-77-0
  • Mol. F.C13H14N2O3
  • Mol. W.246.26 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 5
Lenvatinib Impurity 5
  • CAT. No.L840025
  • CAS. No.2613141-84-5
  • Mol. F.C31H29ClN6O6
  • Mol. W.617.05 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 18
Lenvatinib Impurity 18
  • CAT. No.L840026
  • CAS. No.2143930-75-8
  • Mol. F.C35H26Cl2N6O7
  • Mol. W.713.52 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 20
Lenvatinib Impurity 20
  • CAT. No.L840027
  • CAS. No.NA
  • Mol. F.C19H16ClN3O4
  • Mol. W.385.80 g/mol
  • Stock Status:Custom Synthesis
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Carbamoyl Derivative Of Lenvatinib
Carbamoyl Derivative Of Lenvatinib
  • CAT. No.L840028
  • CAS. No.NA
  • Mol. F.C25H24ClN5O5
  • Mol. W.509.94 g/mol
  • Stock Status:Limited Stock
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Lenvatinib Impurity 29
Lenvatinib Impurity 29
  • CAT. No.L840029
  • CAS. No.NA
  • Mol. F.C31H22ClN3O7
  • Mol. W.583.98 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib N-Ethyl Impurity
Lenvatinib N-Ethyl Impurity
  • CAT. No.L840030
  • CAS. No.417719-46-1
  • Mol. F.C20H19ClN4O4
  • Mol. W.414.85 g/mol
  • Stock Status:Instock
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N-Nitroso Lenvatinib
N-Nitroso Lenvatinib
  • CAT. No.L840032
  • CAS. No.NA
  • Mol. F.C21H18ClN5O5
  • Mol. W.455.85 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 11
Lenvatinib Impurity 11
  • CAT. No.L840033
  • CAS. No.2712530-40-8
  • Mol. F.C45H42Cl2N8O8
  • Mol. W.893.80 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 31
Lenvatinib Impurity 31
  • CAT. No.L840034
  • CAS. No.417714-14-8
  • Mol. F.C21H20N4O4
  • Mol. W.392.41 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 33
Lenvatinib Impurity 33
  • CAT. No.L840035
  • CAS. No.1190837-18-3
  • Mol. F.C11H9NO4
  • Mol. W.219.19 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 32
Lenvatinib Impurity 32
  • CAT. No.L840036
  • CAS. No.1069122-99-1
  • Mol. F.C7H7ClN2O2
  • Mol. W.186.60 g/mol
  • Stock Status:Custom Synthesis
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Desamino Hydroxy Descyclopropyl Lenvatinib
Desamino Hydroxy Descyclopropyl Lenvatinib
  • CAT. No.L840037
  • CAS. No.2733083-03-7
  • Mol. F.C18H14ClN3O5
  • Mol. W.387.77 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 12
Lenvatinib Impurity 12
  • CAT. No.L840038
  • CAS. No.2712290-12-3
  • Mol. F.C17H13ClN2O4
  • Mol. W.344.75 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 34
Lenvatinib Impurity 34
  • CAT. No.L840039
  • CAS. No.796848-80-1
  • Mol. F.C13H10ClNO3
  • Mol. W.263.68 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 25
Lenvatinib Impurity 25
  • CAT. No.L840040
  • CAS. No.205448-64-2
  • Mol. F.C16H17NO7
  • Mol. W.335.31 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Nitrile Impurity
Lenvatinib Nitrile Impurity
  • CAT. No.L840041
  • CAS. No.2983068-19-3
  • Mol. F.C24H16ClN3O4
  • Mol. W.445.86 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 4
Lenvatinib Impurity 4
  • CAT. No.L840042
  • CAS. No.2380197-90-8
  • Mol. F.C28H22ClN5O5
  • Mol. W.543.96 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 35
Lenvatinib Impurity 35
  • CAT. No.L840043
  • CAS. No.NA
  • Mol. F.C24H17Cl2N3O5
  • Mol. W.498.31 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 36
Lenvatinib Impurity 36
  • CAT. No.L840044
  • CAS. No.NA
  • Mol. F.C24H17Cl2N3O5
  • Mol. W.498.31 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 3
Lenvatinib Impurity 3
  • CAT. No.L840045
  • CAS. No.2250242-56-7
  • Mol. F.C23H19ClN4O4
  • Mol. W.450.88 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 7
Lenvatinib Impurity 7
  • CAT. No.L840046
  • CAS. No.17609-80-2
  • Mol. F.C6H6ClNO
  • Mol. W.143.57 g/mol
  • Stock Status:Instock
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Lenvatinib Impurity 19
Lenvatinib Impurity 19
  • CAT. No.L840047
  • CAS. No.2839104-94-6
  • Mol. F.C12H12N2O3
  • Mol. W.232.24 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 37
Lenvatinib Impurity 37
  • CAT. No.L840048
  • CAS. No.417721-15-4
  • Mol. F.C11H8N2O2
  • Mol. W.200.19 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib 4-Chloro Impurity
Lenvatinib 4-Chloro Impurity
  • CAT. No.L840049
  • CAS. No.771464-30-3
  • Mol. F.C11H8ClNO3
  • Mol. W.237.64 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 38
Lenvatinib Impurity 38
  • CAT. No.L840050
  • CAS. No.NA
  • Mol. F.C7H7Cl2NO
  • Mol. W.192.04 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 39
Lenvatinib Impurity 39
  • CAT. No.L840051
  • CAS. No.873417-25-5
  • Mol. F.C7H8ClNO
  • Mol. W.157.60 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 28
Lenvatinib Impurity 28
  • CAT. No.L840052
  • CAS. No.2412398-76-4
  • Mol. F.C25H24ClN5O5
  • Mol. W.509.94 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 40
Lenvatinib Impurity 40
  • CAT. No.L840053
  • CAS. No.39183-17-0
  • Mol. F.C6H5Cl2NO
  • Mol. W.178.02 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 9
Lenvatinib Impurity 9
  • CAT. No.L840054
  • CAS. No.NA
  • Mol. F.C17H13Cl2N3O3
  • Mol. W.378.20 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 10
Lenvatinib Impurity 10
  • CAT. No.L840055
  • CAS. No.NA
  • Mol. F.C17H13Cl2N3O3
  • Mol. W.378.20 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 17
Lenvatinib Impurity 17
  • CAT. No.L840056
  • CAS. No.NA
  • Mol. F.C24H17Cl2N3O5
  • Mol. W.498.30 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 22
Lenvatinib Impurity 22
  • CAT. No.L840057
  • CAS. No.NA
  • Mol. F.C24H17Cl2N3O5
  • Mol. W.498.31 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 23
Lenvatinib Impurity 23
  • CAT. No.L840058
  • CAS. No.NA
  • Mol. F.C21H18Cl2N4O4
  • Mol. W.461.30 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 24
Lenvatinib Impurity 24
  • CAT. No.L840059
  • CAS. No.NA
  • Mol. F.C21H18Cl2N4O4
  • Mol. W.461.30 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Methoxy Impurity
Lenvatinib Methoxy Impurity
  • CAT. No.L840060
  • CAS. No.417724-81-3
  • Mol. F.C11H10N2O3
  • Mol. W.218.20 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 26
Lenvatinib Impurity 26
  • CAT. No.L840061
  • CAS. No.27845-65-4
  • Mol. F.C7H13N
  • Mol. W.111.19 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurirty 1
Lenvatinib Impurirty 1
  • CAT. No.L840062
  • CAS. No.NA
  • Mol. F.C18H15ClN4O4.CH4O3S
  • Mol. W.482.89 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 2
Lenvatinib Impurity 2
  • CAT. No.L840063
  • CAS. No.NA
  • Mol. F.C20H19ClN4O4.CH4O3S
  • Mol. W.510.95 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 27
Lenvatinib Impurity 27
  • CAT. No.L840064
  • CAS. No.2991278-65-8
  • Mol. F.C20H19ClN4O4.CH4O3S
  • Mol. W.510.95 g/mol
  • Stock Status:Custom Synthesis
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Lenvatinib Impurity 30
Lenvatinib Impurity 30
  • CAT. No.L840065
  • CAS. No.6228-73-5
  • Mol. F.C4H7NO
  • Mol. W.85.10 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Phenoxy Quinoline
N-Nitroso Phenoxy Quinoline
  • CAT. No.L840066
  • CAS. No.NA
  • Mol. F.C17H13ClN4O4
  • Mol. W.372.76 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Lenvatinib-D4
Lenvatinib-D4
  • CAT. No.L840004
  • CAS. No.NA
  • Mol. F.C21H15D4ClN4O4
  • Mol. W.430.88 g/mol
  • Stock Status:Under Synthesis
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Lenvatinib D5
Lenvatinib D5
  • CAT. No.L840011
  • CAS. No.NA
  • Mol. F.C21H14D5ClN4O4
  • Mol. W.431.88 g/mol
  • Stock Status:Custom Synthesis
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