Lamotrigine Related Compounds & Impurities

Lamotrigine is an anticonvulsant that inhibits voltage-sensitive sodium channels and glutamate release, used for epilepsy and bipolar disorder maintenance.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Lamotrigine reference standards, pharmacopeial and non-pharmacopeial Lamotrigine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Lamotrigine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Lamotrigine
Lamotrigine
  • CAT. No.L010000
  • CAS. No.84057-84-1
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity A
Lamotrigine EP Impurity A
  • CAT. No.L010001
  • CAS. No.252186-78-0
  • Mol. F.C9H6Cl2N4O
  • Mol. W.257.08 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity B
Lamotrigine EP Impurity B
  • CAT. No.L010002
  • CAS. No.94213-24-8
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity C
Lamotrigine EP Impurity C
  • CAT. No.L010003
  • CAS. No.94213-23-7
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity C Pentahydrate
Lamotrigine EP Impurity C Pentahydrate
  • CAT. No.L010003A
  • CAS. No.94213-23-7(free base)
  • Mol. F.C9H7Cl2N5.5H2O
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine Impurity 25
Lamotrigine Impurity 25
  • CAT. No.L010003B
  • CAS. No.84689-20-3
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity D
Lamotrigine EP Impurity D
  • CAT. No.L010004
  • CAS. No.661463-79-2
  • Mol. F.C9H5Cl2N3O2
  • Mol. W.258.06 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity E
Lamotrigine EP Impurity E
  • CAT. No.L010005
  • CAS. No.50-45-3
  • Mol. F.C7H4Cl2O2
  • Mol. W.191.01 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity F
Lamotrigine EP Impurity F
  • CAT. No.L010006
  • CAS. No.252186-79-1
  • Mol. F.C16H9Cl4N5O
  • Mol. W.429.09 g/mol
  • Stock Status:Instock
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Lamotrigine EP Impurity-G
Lamotrigine EP Impurity-G
  • CAT. No.L010007
  • CAS. No.38943-76-9
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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2,3-Dichlorobenzoyl Cyanide
2,3-Dichlorobenzoyl Cyanide
  • CAT. No.L010008
  • CAS. No.77668-42-9
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Instock
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2,3-Dichloro Benzoyl chloride
2,3-Dichloro Benzoyl chloride
  • CAT. No.L010011
  • CAS. No.2905-60-4
  • Mol. F.C7H3Cl3O
  • Mol. W.209.46 g/mol
  • Stock Status:Instock
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Lamotrigine Impurity 24
Lamotrigine Impurity 24
  • CAT. No.L010013
  • CAS. No.84689-20-3
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine 3,3-Dimer
Lamotrigine 3,3-Dimer
  • CAT. No.L010015
  • CAS. No.1797983-48-2
  • Mol. F.C19H14Cl4N10
  • Mol. W.524.19 g/mol
  • Stock Status:Custom Synthesis
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2,4 Dichlorobenzoyl Nitrile
2,4 Dichlorobenzoyl Nitrile
  • CAT. No.L010016
  • CAS. No.35022-43-6
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Instock
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2,3-Dichlorobenzoic Anhydride
2,3-Dichlorobenzoic Anhydride
  • CAT. No.L010017
  • CAS. No.51417-52-8
  • Mol. F.C14H6Cl4O3
  • Mol. W.364.01 g/mol
  • Stock Status:Instock
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3,4-dichloro benzoyl nitrile
3,4-dichloro benzoyl nitrile
  • CAT. No.L010018
  • CAS. No.35022-44-7
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Custom Synthesis
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2,5-Dichlorobenzoyl cyanide
2,5-Dichlorobenzoyl cyanide
  • CAT. No.L010019
  • CAS. No.64985-85-9
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Instock
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Lamotrigine-2-N-Oxide
Lamotrigine-2-N-Oxide
  • CAT. No.L010022
  • CAS. No.136565-76-9
  • Mol. F.C9H7Cl2N5O
  • Mol. W.272.09 g/mol
  • Stock Status:Instock
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2,3-Dichlorobenzoyl Chloride
2,3-Dichlorobenzoyl Chloride
  • CAT. No.L010023
  • CAS. No.2905-60-4
  • Mol. F.C7H3Cl3O
  • Mol. W.209.46 g/mol
  • Stock Status:Under Synthesis
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Lamotrigine 5,5-Dimer
Lamotrigine 5,5-Dimer
  • CAT. No.L010025
  • CAS. No.NA
  • Mol. F.C19H14Cl4N10
  • Mol. W.524.19 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Hydroxyl Amine
Lamotrigine Hydroxyl Amine
  • CAT. No.L010026
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5O
  • Mol. W.272.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 2
Lamotrigine Impurity 2
  • CAT. No.L010027
  • CAS. No.94266-27-0
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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2-[(2,5-dichlorophenyl)-cyanomethylene]-hydrazine carboximidamide
2-[(2,5-dichlorophenyl)-cyanomethylene]-hydrazine carboximidamide
  • CAT. No.L010028
  • CAS. No.94213-25-9
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine Impurity 4
Lamotrigine Impurity 4
  • CAT. No.L010029
  • CAS. No.356757-50-1
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Instock
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Lamotrigine-13C3,d3
Lamotrigine-13C3,d3
  • CAT. No.L010030
  • CAS. No.1246815-13-3
  • Mol. F.C613C3H4D3Cl2N5
  • Mol. W.262.09 g/mol
  • Stock Status:Custom Synthesis
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6-(3-bromo-2-chlorophenyl)-1,2,4-trazine-3,5-diamine
6-(3-bromo-2-chlorophenyl)-1,2,4-trazine-3,5-diamine
  • CAT. No.L010031
  • CAS. No.NA
  • Mol. F.C9H7BrClN5
  • Mol. W.300.54 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 6
Lamotrigine Impurity 6
  • CAT. No.L010032
  • CAS. No.NA
  • Mol. F.C9H7BrClN5
  • Mol. W.300.54 g/mol
  • Stock Status:Custom Synthesis
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3-amino-6-(2,3-dichlorophenyl)-5-hydroxyamino-1,2,4-triazine
3-amino-6-(2,3-dichlorophenyl)-5-hydroxyamino-1,2,4-triazine
  • CAT. No.L010033
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5O
  • Mol. W.272.09 g/mol
  • Stock Status:Custom Synthesis
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2-(2,3-dichlorobenzoyl)hydrazinecarboximidamide
2-(2,3-dichlorobenzoyl)hydrazinecarboximidamide
  • CAT. No.L010034
  • CAS. No.887354-37-2
  • Mol. F.C8H8Cl2N4O
  • Mol. W.247.08 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine N-Oxide
Lamotrigine N-Oxide
  • CAT. No.L010036
  • CAS. No.1426543-66-9
  • Mol. F.C9H7Cl2N5O
  • Mol. W.272.09 g/mol
  • Stock Status:Limited Stock
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2,3-Dichlorobenzoic Acid Anhydride
2,3-Dichlorobenzoic Acid Anhydride
  • CAT. No.L010037
  • CAS. No.252186-80-4
  • Mol. F.C14H6Cl4O3
  • Mol. W.364.01 g/mol
  • Stock Status:Custom Synthesis
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N-guanidinyl-2,3-dichlorobenzamide
N-guanidinyl-2,3-dichlorobenzamide
  • CAT. No.L010038
  • CAS. No.NA
  • Mol. F.C8H8Cl2N4O
  • Mol. W.247.08 g/mol
  • Stock Status:Custom Synthesis
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2,6-Dichlorobenzyl chloride
2,6-Dichlorobenzyl chloride
  • CAT. No.L010040
  • CAS. No.2014-83-7
  • Mol. F.C7H5Cl3
  • Mol. W.195.47 g/mol
  • Stock Status:Instock
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2,6-dichlorobenzoic acid
2,6-dichlorobenzoic acid
  • CAT. No.L010041
  • CAS. No.50-30-6
  • Mol. F.C7H4Cl2O2
  • Mol. W.191.01 g/mol
  • Stock Status:Custom Synthesis
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2,5-dichlorobenzoic acid
2,5-dichlorobenzoic acid
  • CAT. No.L010042
  • CAS. No.50-79-3
  • Mol. F.C7H4Cl2O2
  • Mol. W.191.01 g/mol
  • Stock Status:Instock
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3,4-dichlorobenzoic acid
3,4-dichlorobenzoic acid
  • CAT. No.L010043
  • CAS. No.51-44-5
  • Mol. F.C7H4Cl2O2
  • Mol. W.191.01 g/mol
  • Stock Status:Custom Synthesis
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2,6-Dichlorobenzoyl Cyanide
2,6-Dichlorobenzoyl Cyanide
  • CAT. No.L010045
  • CAS. No.88562-25-8
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Open Ring Dimer
Lamotrigine Open Ring Dimer
  • CAT. No.L010046
  • CAS. No.NA
  • Mol. F.C15H10Cl4N2O2
  • Mol. W.392.06 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 7
Lamotrigine Impurity 7
  • CAT. No.L010047
  • CAS. No.35022-42-5
  • Mol. F.C8H4ClNO
  • Mol. W.165.58 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 9
Lamotrigine Impurity 9
  • CAT. No.L010049
  • CAS. No.13014-48-7
  • Mol. F.C8H4ClNO
  • Mol. W.165.58 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 10
Lamotrigine Impurity 10
  • CAT. No.L010050
  • CAS. No.99567-74-5
  • Mol. F.C8H3Cl2NO
  • Mol. W.200.02 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 3
Lamotrigine Impurity 3
  • CAT. No.L010051
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 5
Lamotrigine Impurity 5
  • CAT. No.L010052
  • CAS. No.NA
  • Mol. F.C9H8ClN5
  • Mol. W.221.65 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 8
Lamotrigine Impurity 8
  • CAT. No.L010053
  • CAS. No.77668-43-0
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.10 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 11
Lamotrigine Impurity 11
  • CAT. No.L010054
  • CAS. No.NA
  • Mol. F.C9H8ClN5
  • Mol. W.221.65 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 12
Lamotrigine Impurity 12
  • CAT. No.L010055
  • CAS. No.6662-28-8
  • Mol. F.C9H8ClN5
  • Mol. W.221.65 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 13
Lamotrigine Impurity 13
  • CAT. No.L010056
  • CAS. No.NA
  • Mol. F.C9H8ClN5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 14
Lamotrigine Impurity 14
  • CAT. No.L010057
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 15
Lamotrigine Impurity 15
  • CAT. No.L010058
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 17
Lamotrigine Impurity 17
  • CAT. No.L010060
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 18
Lamotrigine Impurity 18
  • CAT. No.L010061
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 19
Lamotrigine Impurity 19
  • CAT. No.L010062
  • CAS. No.NA
  • Mol. F.C9H8ClN5
  • Mol. W.221.65 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 20
Lamotrigine Impurity 20
  • CAT. No.L010063
  • CAS. No.NA
  • Mol. F.C9H8ClN5
  • Mol. W.221.65 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 21
Lamotrigine Impurity 21
  • CAT. No.L010064
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Impurity 22
Lamotrigine Impurity 22
  • CAT. No.L010065
  • CAS. No.NA
  • Mol. F.C9H7Cl2N5
  • Mol. W.256.09 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Diamide Impurity
Lamotrigine Diamide Impurity
  • CAT. No.L010066
  • CAS. No.1373393-59-9
  • Mol. F.C23H11Cl6N5O2
  • Mol. W.602.10 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Nitroso impurity 1
Lamotrigine Nitroso impurity 1
  • CAT. No.L010067
  • CAS. No.42363-85-9
  • Mol. F.H3N3O
  • Mol. W.61.00 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine Nitroso impurity 2
Lamotrigine Nitroso impurity 2
  • CAT. No.L010068
  • CAS. No.NA
  • Mol. F.H2N4O2
  • Mol. W.90.00 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine impurity 23
Lamotrigine impurity 23
  • CAT. No.L010069
  • CAS. No.26152-02-3
  • Mol. F.C8H4ClNO
  • Mol. W.165.58 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Lamotrigine N2-Glucuronide
Lamotrigine N2-Glucuronide
  • CAT. No.L010010
  • CAS. No.133310-19-7
  • Mol. F.C15H16Cl2N5O6
  • Mol. W.433.22 g/mol
  • Stock Status:Limited Stock
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Lamotrigine 5 N Glucuronide
Lamotrigine 5 N Glucuronide
  • CAT. No.L010039
  • CAS. No.136565-77-0
  • Mol. F.C15H15Cl2N5O6
  • Mol. W.432.22 g/mol
  • Stock Status:Under Synthesis
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Isotope Labelled Compounds

Lamotrigine-13C,D3
Lamotrigine-13C,D3
  • CAT. No.L010021
  • CAS. No.2517756-06-6
  • Mol. F.C813CH4D3Cl2N5
  • Mol. W.260.10 g/mol
  • Stock Status:Limited Stock
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[13C7,15N]-Lamotrigine
[13C7,15N]-Lamotrigine
  • CAT. No.L010035
  • CAS. No.84057-84-1(unlabeled)
  • Mol. F.C213C7H7Cl2N415N
  • Mol. W.264.03 g/mol
  • Stock Status:Custom Synthesis
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Lamotrigine-D3
Lamotrigine-D3
  • CAT. No.L010044
  • CAS. No.84057-84-1(unlabelled)
  • Mol. F.C9H4D3Cl2N5
  • Mol. W.259.11 g/mol
  • Stock Status:Custom Synthesis
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