Ketoconazole Related Compounds & Impurities

Ketoconazole is an imidazole antifungal that inhibits CYP51 and steroidogenic enzymes, used topically for dermatophytosis and seborrhoeic dermatitis.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Ketoconazole reference standards, pharmacopeial and non-pharmacopeial Ketoconazole impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Ketoconazole-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Ketoconazole
Ketoconazole
  • CAT. No.K070000
  • CAS. No.65277-42-1
  • Mol. F.C26H28Cl2N4O4
  • Mol. W.531.43 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity D
Ketoconazole Impurity D
  • CAT. No.K070001
  • CAS. No.67914-61-8
  • Mol. F.C24H26Cl2N4O3
  • Mol. W.489.39 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity B
Ketoconazole Impurity B
  • CAT. No.K070002
  • CAS. No.1346598-39-7
  • Mol. F.C38H42Cl2N6O6
  • Mol. W.749.69 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Ketoconazole Impurity C
Ketoconazole Impurity C
  • CAT. No.K070003
  • CAS. No.83374-59-8
  • Mol. F.C26H28Cl2N4O4
  • Mol. W.531.43 g/mol
  • Stock Status:Limited Stock
Product View
Product Compare
Ketoconazole EP Impurity E
Ketoconazole EP Impurity E
  • CAT. No.K070004
  • CAS. No.134071-44-6
  • Mol. F.C21H20Cl2N2O5S
  • Mol. W.483.37 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity 11
Ketoconazole Impurity 11
  • CAT. No.K070005
  • CAS. No.67914-60-7
  • Mol. F.C12H16N2O2
  • Mol. W.220.27 g/mol
  • Stock Status:Instock
Product View
Product Compare
trans-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate
trans-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate
  • CAT. No.K070007
  • CAS. No.61397-57-7
  • Mol. F.C18H15BrCl2O4
  • Mol. W.446.12 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole N-Oxide
Ketoconazole N-Oxide
  • CAT. No.K070008
  • CAS. No.1392277-16-5
  • Mol. F.C26H28Cl2N4O5
  • Mol. W.547.43 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity 1
Ketoconazole Impurity 1
  • CAT. No.K070009
  • CAS. No.581806-59-9
  • Mol. F.C12H14N2O2
  • Mol. W.218.25 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N,N-Diamylnitrosamine
N,N-Diamylnitrosamine
  • CAT. No.K070010
  • CAS. No.13256-06-9
  • Mol. F.C10H22N2O
  • Mol. W.186.29 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Hydroxymethyl Impurity
Ketoconazole Hydroxymethyl Impurity
  • CAT. No.K070011
  • CAS. No.170210-42-1
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Ketoconazole EP Impurity A
Ketoconazole EP Impurity A
  • CAT. No.K070012
  • CAS. No.254912-63-5
  • Mol. F.C26H26Cl2N4O4
  • Mol. W.529.42 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Ketoconazole Impurity 3
Ketoconazole Impurity 3
  • CAT. No.K070014
  • CAS. No.170210-49-8
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 10
Ketoconazole Impurity 10
  • CAT. No.K070015
  • CAS. No.61441-65-4
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
KetoconazoleHydroxymethyl Impurity
KetoconazoleHydroxymethyl Impurity
  • CAT. No.K070016
  • CAS. No.170210-42-1
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Instock
Product View
Product Compare
Trans-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
Trans-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
  • CAT. No.K070017
  • CAS. No.61441-65-4
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 17
Ketoconazole Impurity 17
  • CAT. No.K070018
  • CAS. No.61397-58-8
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Instock
Product View
Product Compare
Cis-bromo mesylate
Cis-bromo mesylate
  • CAT. No.K070019
  • CAS. No.NA
  • Mol. F.C12H13BrCl2O5S
  • Mol. W.420.10 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Cis-tosylate Ketoconazole
Cis-tosylate Ketoconazole
  • CAT. No.K070020
  • CAS. No.2095256-87-2
  • Mol. F.C21H20Cl2N2O5S
  • Mol. W.483.36 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
1-(4-(4-((2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethano
1-(4-(4-((2-((1H-imidazol-1-yl)methyl)-2-(2-chlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethano
  • CAT. No.K070021
  • CAS. No.NA
  • Mol. F.C26H29ClN4O4
  • Mol. W.496.99 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 20
Ketoconazole Impurity 20
  • CAT. No.K070022
  • CAS. No.91458-32-1
  • Mol. F.C26H29ClN4O4
  • Mol. W.496.99 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Cis Tosylate
Cis Tosylate
  • CAT. No.K070023
  • CAS. No.154003-23-3
  • Mol. F.C20H19Cl2N3O5S
  • Mol. W.484.35 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 15
Ketoconazole Impurity 15
  • CAT. No.K070025
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O7S
  • Mol. W.611.49 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 22
Ketoconazole Impurity 22
  • CAT. No.K070026
  • CAS. No.1253852-50-4
  • Mol. F.C24H26Cl2N4O4
  • Mol. W.505.39 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Levoketoconazole
Levoketoconazole
  • CAT. No.K070027
  • CAS. No.142128-57-2
  • Mol. F.C26H28Cl2N4O4
  • Mol. W.531.43 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity 21
Ketoconazole Impurity 21
  • CAT. No.K070028
  • CAS. No.98207-06-8
  • Mol. F.C23H25BrCl2N2O4
  • Mol. W.544.27 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 19
Ketoconazole Impurity 19
  • CAT. No.K070029
  • CAS. No.98405-42-6
  • Mol. F.C23H25BrCl2N2O4
  • Mol. W.544.27 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Nitroso EP Impurity D
Ketoconazole Nitroso EP Impurity D
  • CAT. No.K070030
  • CAS. No.NA
  • Mol. F.C24H25Cl2N5O4
  • Mol. W.518.39 g/mol
  • Stock Status:Instock
Product View
Product Compare
4-(4-nitrosopiperazin-1-yl)Phenol
4-(4-nitrosopiperazin-1-yl)Phenol
  • CAT. No.K070031
  • CAS. No.NA
  • Mol. F.C10H13N3O2
  • Mol. W.207.23 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole Impurity 11
Ketoconazole Impurity 11
  • CAT. No.K070032
  • CAS. No.NA
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 12
Ketoconazole Impurity 12
  • CAT. No.K070033
  • CAS. No.NA
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole N-Oxide Impurity
Ketoconazole N-Oxide Impurity
  • CAT. No.K070034
  • CAS. No.254912-65-7
  • Mol. F.C26H28Cl2N4O5
  • Mol. W.547.43 g/mol
  • Stock Status:Instock
Product View
Product Compare
2-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpiperazin-1-yl)phenyl hydrogen sulfite
2-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpiperazin-1-yl)phenyl hydrogen sulfite
  • CAT. No.K070035
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O7S
  • Mol. W.611.49 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 2
Ketoconazole Impurity 2
  • CAT. No.K070036
  • CAS. No.NA
  • Mol. F.C26H26Cl2N4O4
  • Mol. W.529.42 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 26
Ketoconazole Impurity 26
  • CAT. No.K070037
  • CAS. No.133345-21-8
  • Mol. F.C14H18N2O3
  • Mol. W.262.30 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 27
Ketoconazole Impurity 27
  • CAT. No.K070038
  • CAS. No.112190-13-3
  • Mol. F.C11H14N2O2
  • Mol. W.206.20 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
[2-(4-acetylpiperazin-1-yl)-5-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl]oxidanesulfinic acid
[2-(4-acetylpiperazin-1-yl)-5-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl]oxidanesulfinic acid
  • CAT. No.K070039
  • CAS. No.NA
  • Mol. F.C28H30Cl2N4O7S
  • Mol. W.637.53 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
[5-(4-acetylpiperazin-1-yl)-2-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl]oxidanesulfinic acid
[5-(4-acetylpiperazin-1-yl)-2-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl]oxidanesulfinic acid
  • CAT. No.K070040
  • CAS. No.NA
  • Mol. F.C28H30Cl2N4O7S
  • Mol. W.637.53 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
5-(4-acetylpiperazin-1-yl)-2-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}benzene-1-sulfonic acid
5-(4-acetylpiperazin-1-yl)-2-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}benzene-1-sulfonic acid
  • CAT. No.K070041
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O7S
  • Mol. W.611.49 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
2-(4-acetylpiperazin-1-yl)-5-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}benzene-1-sulfonic acid
2-(4-acetylpiperazin-1-yl)-5-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}benzene-1-sulfonic acid
  • CAT. No.K070042
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O7S
  • Mol. W.611.49 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurities Mixture 1:1:1
Ketoconazole Impurities Mixture 1:1:1
  • CAT. No.K070043
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 32
Ketoconazole Impurity 32
  • CAT. No.K070045
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O4.H2O3S
  • Mol. W.613.51 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 31
Ketoconazole Impurity 31
  • CAT. No.K070046
  • CAS. No.158985-25-2
  • Mol. F.C15H22N2O3
  • Mol. W.278.35 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Ketoconazole Hydroxy Impurity
Ketoconazole Hydroxy Impurity
  • CAT. No.K070047
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O5
  • Mol. W.547.43 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 33
Ketoconazole Impurity 33
  • CAT. No.K070048
  • CAS. No.84682-23-5
  • Mol. F.C14H14Cl2N2O3
  • Mol. W.329.18 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 34
Ketoconazole Impurity 34
  • CAT. No.K070049
  • CAS. No.142128-59-4
  • Mol. F.C26H28Cl2N4O4
  • Mol. W.531.43 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 35
Ketoconazole Impurity 35
  • CAT. No.K070050
  • CAS. No.NA
  • Mol. F.C26H20Cl2N4O9
  • Mol. W.603.36 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole N-Oxide Impurity 1
Ketoconazole N-Oxide Impurity 1
  • CAT. No.K070051
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O5
  • Mol. W.547.43 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Levoketoconazole N-Oxide
Levoketoconazole N-Oxide
  • CAT. No.K070052
  • CAS. No.NA
  • Mol. F.C26H28Cl2N4O5
  • Mol. W.547.43 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole Impurity 4
Ketoconazole Impurity 4
  • CAT. No.K070053
  • CAS. No.1334423-12-9
  • Mol. F.C26H29ClN4O4
  • Mol. W.496.99 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole impurity 5
Ketoconazole impurity 5
  • CAT. No.K070054
  • CAS. No.NA
  • Mol. F.C26H26Cl2N4O5
  • Mol. W.545.41 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Ketoconazole impurity 6
Ketoconazole impurity 6
  • CAT. No.K070057
  • CAS. No.497250-93-8
  • Mol. F.C11H10BrCl3O2
  • Mol. W.360.50 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare

Metabolites

Ketoconazole Glucuronide
Ketoconazole Glucuronide
  • CAT. No.K070024
  • CAS. No.NA
  • Mol. F.C32H36Cl2N4O10
  • Mol. W.707.56 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare

Isotope Labelled Compounds

Ketoconazole D3
Ketoconazole D3
  • CAT. No.K070006
  • CAS. No.1217766-70-5
  • Mol. F.C26H25Cl2D3N4O4
  • Mol. W.534.46 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Levoketoconazole D3
Levoketoconazole D3
  • CAT. No.K070044
  • CAS. No.NA
  • Mol. F.C26H25D3Cl2N4O4
  • Mol. W.534.45 g/mol
  • Stock Status:Instock
Product View
Product Compare
Ketoconazole D4
Ketoconazole D4
  • CAT. No.K070055
  • CAS. No.1398065-75-2
  • Mol. F.C26H24D4Cl2N4O4
  • Mol. W.535.46 g/mol
  • Stock Status:Please Enquire
Product View
Product Compare
Ketoconazole D8
Ketoconazole D8
  • CAT. No.K070056
  • CAS. No.1217706-96-1
  • Mol. F.C26H20D8Cl2N4O4
  • Mol. W.539.48 g/mol
  • Stock Status:Please Enquire
Product View
Product Compare