Icatibant Acetate Related Compounds & Impurities

Icatibant Acetate is a selective bradykinin B2 receptor antagonist used for acute attacks of hereditary angioedema.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Icatibant Acetate reference standards, pharmacopeial and non-pharmacopeial Icatibant Acetate impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Icatibant Acetate-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Icatibant Acetate
Icatibant Acetate
  • CAT. No.I510000
  • CAS. No.138614-30-9
  • Mol. F.C59H89N19O13S.C2H4O2
  • Mol. W.1346.56 g/mol
  • Stock Status:Custom Synthesis
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D-Thi(6)-Icatibant
D-Thi(6)-Icatibant
  • CAT. No.I510001
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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Des[Pro(3)-Hyp(4)]-Icatibant
Des[Pro(3)-Hyp(4)]-Icatibant
  • CAT. No.I510002
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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D-Ser (7) Icatibant
D-Ser (7) Icatibant
  • CAT. No.I510003
  • CAS. No.193618-64-3 (free base)
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.53 g/mol
  • Stock Status:Custom Synthesis
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Des[Pro(3)- Hyp(4)]-Icatibant Epimer
Des[Pro(3)- Hyp(4)]-Icatibant Epimer
  • CAT. No.I510004
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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D-Arg(10)-Icatibant
D-Arg(10)-Icatibant
  • CAT. No.I510005
  • CAS. No.193618-62-1
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.52 g/mol
  • Stock Status:Custom Synthesis
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D-Pro(3)-Icatibant
D-Pro(3)-Icatibant
  • CAT. No.I510006
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.50 g/mol
  • Stock Status:Custom Synthesis
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N-terminal Acetylated Icatibant [Ac-D-Arg(1)-ICA]
N-terminal Acetylated Icatibant [Ac-D-Arg(1)-ICA]
  • CAT. No.I510009
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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D-Arg-Arg-Pro-Hyp-Gly-Thi-D-Ser-D-Tic-Oic-Arg-OH
D-Arg-Arg-Pro-Hyp-Gly-Thi-D-Ser-D-Tic-Oic-Arg-OH
  • CAT. No.I510015
  • CAS. No.NA
  • Mol. F.C60H89F3N20O14S
  • Mol. W.1403.53 g/mol
  • Stock Status:Custom Synthesis
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Arg-Pro-Hyp-Gly-Thi-D-Ser-D-Tic-Oic-Arg-OH
Arg-Pro-Hyp-Gly-Thi-D-Ser-D-Tic-Oic-Arg-OH
  • CAT. No.I510016
  • CAS. No.NA
  • Mol. F.C53H77N15O12S
  • Mol. W.1448.34 g/mol
  • Stock Status:Custom Synthesis
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AC-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
AC-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
  • CAT. No.I510017
  • CAS. No.NA
  • Mol. F.C61H91N19O14S
  • Mol. W.1346.58 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 6 Dihydrochloride
Icatibant Impurity 6 Dihydrochloride
  • CAT. No.I510019
  • CAS. No.NA
  • Mol. F.C25H36Cl2N6O5
  • Mol. W.571.50 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Acetate Impurity A
Icatibant Acetate Impurity A
  • CAT. No.I510026
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.52 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Acetate Impurity B
Icatibant Acetate Impurity B
  • CAT. No.I510027
  • CAS. No.NA
  • Mol. F.C53H77N15O12S
  • Mol. W.1148.34 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Acetate Impurity C
Icatibant Acetate Impurity C
  • CAT. No.I510028
  • CAS. No.NA
  • Mol. F.C53H77N15O12S
  • Mol. W.1148.34 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Tetra-Acetate
Icatibant Tetra-Acetate
  • CAT. No.I510029
  • CAS. No.NA
  • Mol. F.C59H89N19O13S.4C2HF3O2
  • Mol. W.1760.62 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 7 Tri-Trifluoroacetate
Icatibant Impurity 7 Tri-Trifluoroacetate
  • CAT. No.I510030
  • CAS. No.NA
  • Mol. F.C40H58N13O16SF9
  • Mol. W.1180.01 g/mol
  • Stock Status:Custom Synthesis
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Icatibant[1-5]-ITBT
Icatibant[1-5]-ITBT
  • CAT. No.I510031
  • CAS. No.NA
  • Mol. F.C24H43N11O7
  • Mol. W.597.67 g/mol
  • Stock Status:Custom Synthesis
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Icatibant [8-10]-ITBT
Icatibant [8-10]-ITBT
  • CAT. No.I510032
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [1-7]
Icatibant Peptide Fragment [1-7]
  • CAT. No.I510033
  • CAS. No.NA
  • Mol. F.C34H55N13O10S
  • Mol. W.837.96 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [9-10]
Icatibant Peptide Fragment [9-10]
  • CAT. No.I510034
  • CAS. No.NA
  • Mol. F.C15H27N503
  • Mol. W.325.41 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [1-6]
Icatibant Peptide Fragment [1-6]
  • CAT. No.I510035
  • CAS. No.NA
  • Mol. F.C31H50N12O8S
  • Mol. W.750.88 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [Des-Oic9]
Icatibant Peptide Fragment [Des-Oic9]
  • CAT. No.I510036
  • CAS. No.NA
  • Mol. F.C50H76N18O12S
  • Mol. W.1153.33 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [Des-D-Tic8]
Icatibant Peptide Fragment [Des-D-Tic8]
  • CAT. No.I510037
  • CAS. No.NA
  • Mol. F.C49H80N18O12S
  • Mol. W.1145.34 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [D-Oic9]
Icatibant Peptide Fragment [D-Oic9]
  • CAT. No.I510038
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.54 g/mol
  • Stock Status:Instock
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Icatibant Peptide Fragment [7 -10]
Icatibant Peptide Fragment [7 -10]
  • CAT. No.I510039
  • CAS. No.NA
  • Mol. F.C28H41N7O6
  • Mol. W.571.68 g/mol
  • Stock Status:Instock
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Icatibant Peptide Fragment [D-Thi6]
Icatibant Peptide Fragment [D-Thi6]
  • CAT. No.I510040
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.54 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [Des-Pro3]
Icatibant Peptide Fragment [Des-Pro3]
  • CAT. No.I510041
  • CAS. No.NA
  • Mol. F.C54H82N18O12S
  • Mol. W.1207.42 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [D-Cis-Hyp4]
Icatibant Peptide Fragment [D-Cis-Hyp4]
  • CAT. No.I510042
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.54 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [L-Cis-Hyp4]
Icatibant Peptide Fragment [L-Cis-Hyp4]
  • CAT. No.I510043
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.54 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Peptide Fragment [Des-Gly5]
Icatibant Peptide Fragment [Des-Gly5]
  • CAT. No.I510044
  • CAS. No.NA
  • Mol. F.C57H86N18O12S
  • Mol. W.1247.49 g/mol
  • Stock Status:Instock
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Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
  • CAT. No.I510045
  • CAS. No.NA
  • Mol. F.C53H77N15O12S
  • Mol. W.1148.35 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 2
Icatibant Impurity 2
  • CAT. No.I510046
  • CAS. No.NA
  • Mol. F.C59H87N19O14S
  • Mol. W.1318.51 g/mol
  • Stock Status:Custom Synthesis
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L-Arg(1)-Icatibant
L-Arg(1)-Icatibant
  • CAT. No.I510047
  • CAS. No.193618-59-6
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.50 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 3
Icatibant Impurity 3
  • CAT. No.I510048
  • CAS. No.NA
  • Mol. F.C59H87N19O14S
  • Mol. W.1318.51 g/mol
  • Stock Status:Custom Synthesis
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(1-6)-Icatibant
(1-6)-Icatibant
  • CAT. No.I510049
  • CAS. No.2698340-93-9
  • Mol. F.C31H50N12O8S
  • Mol. W.750.90 g/mol
  • Stock Status:Custom Synthesis
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(7-10)-Icatibant
(7-10)-Icatibant
  • CAT. No.I510050
  • CAS. No.148416-85-7
  • Mol. F.C28H41N7O6
  • Mol. W.571.70 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 4
Icatibant Impurity 4
  • CAT. No.I510051
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.52 g/mol
  • Stock Status:Custom Synthesis
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Des-L-Arg(2)-Icatibant
Des-L-Arg(2)-Icatibant
  • CAT. No.I510052
  • CAS. No.193740-38-4
  • Mol. F.C53H77N15O12S
  • Mol. W.1148.40 g/mol
  • Stock Status:Custom Synthesis
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Des-D-Arg(1)-Icatibant
Des-D-Arg(1)-Icatibant
  • CAT. No.I510053
  • CAS. No.130334-60-0
  • Mol. F.C53H77N15O12S
  • Mol. W.1148.40 g/mol
  • Stock Status:Custom Synthesis
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Ac-Icatibant
Ac-Icatibant
  • CAT. No.I510054
  • CAS. No.NA
  • Mol. F.C61H91N19O14S
  • Mol. W.1346.56 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 1
N-Nitroso Icatibant Impurity 1
  • CAT. No.I510055
  • CAS. No.NA
  • Mol. F.C59H87N21O15S
  • Mol. W.1362.52 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 2
N-Nitroso Icatibant Impurity 2
  • CAT. No.I510056
  • CAS. No.NA
  • Mol. F.C53H76N16O13S
  • Mol. W.1177.33 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 3
N-Nitroso Icatibant Impurity 3
  • CAT. No.I510057
  • CAS. No.NA
  • Mol. F.C25H33N7O6
  • Mol. W.527.57 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 4
N-Nitroso Icatibant Impurity 4
  • CAT. No.I510058
  • CAS. No.NA
  • Mol. F.C59H86N20O15S
  • Mol. W.1347.50 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 5
N-Nitroso Icatibant Impurity 5
  • CAT. No.I510059
  • CAS. No.NA
  • Mol. F.C59H86N20O14S
  • Mol. W.1331.50 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 6
N-Nitroso Icatibant Impurity 6
  • CAT. No.I510060
  • CAS. No.NA
  • Mol. F.C10H10N2O3
  • Mol. W.206.20 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 7
N-Nitroso Icatibant Impurity 7
  • CAT. No.I510061
  • CAS. No.NA
  • Mol. F.C15H26N6O4
  • Mol. W.354.40 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 8
N-Nitroso Icatibant Impurity 8
  • CAT. No.I510062
  • CAS. No.NA
  • Mol. F.C15H26N6O4
  • Mol. W.354.40 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 9
N-Nitroso Icatibant Impurity 9
  • CAT. No.I510063
  • CAS. No.NA
  • Mol. F.C15H25N7O5
  • Mol. W.383.40 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 10
N-Nitroso Icatibant Impurity 10
  • CAT. No.I510064
  • CAS. No.NA
  • Mol. F.C60H88N20O14S
  • Mol. W.1345.53 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 11
N-Nitroso Icatibant Impurity 11
  • CAT. No.I510065
  • CAS. No.NA
  • Mol. F.C28H40N8O7
  • Mol. W.600.67 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Icatibant Impurity 12
N-Nitroso Icatibant Impurity 12
  • CAT. No.I510066
  • CAS. No.NA
  • Mol. F.C59H87N21O15S
  • Mol. W.1362.52 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 1
Icatibant Impurity 1
  • CAT. No.I510067
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.52 g/mol
  • Stock Status:Custom Synthesis
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Icatibant Impurity 5
Icatibant Impurity 5
  • CAT. No.I510068
  • CAS. No.NA
  • Mol. F.C59H89N19O13S
  • Mol. W.1304.50 g/mol
  • Stock Status:Custom Synthesis
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D-Ser (7) Icatibant Trifluoroacetic acid
D-Ser (7) Icatibant Trifluoroacetic acid
  • CAT. No.I510069
  • CAS. No.NA
  • Mol. F.C59H89N19O13S.C2HF3O2
  • Mol. W.1420.60 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Endo-Gly:H-D-Arg-Arg-Pro-Hyp-Gly-Gly-Thi-Ser-D
Endo-Gly:H-D-Arg-Arg-Pro-Hyp-Gly-Gly-Thi-Ser-D
  • CAT. No.I510013
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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ICA-(6-10) : H-Thi-Ser-D-Tic-Oic-Arg-OH
ICA-(6-10) : H-Thi-Ser-D-Tic-Oic-Arg-OH
  • CAT. No.I510014
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

N-Nitroso Tadalafil D3
N-Nitroso Tadalafil D3
  • CAT. No.T090069
  • CAS. No.NA
  • Mol. F.C59H89N19O13S.C2HF3O2
  • Mol. W.1420.60 g/mol
  • Stock Status:Please Enquire
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