Ibuprofen Related Compounds & Impurities

Ibuprofen is a non-selective cyclooxygenase inhibitor and propionic acid NSAID, one of the most widely used analgesic, anti-inflammatory and antipyretic agents worldwide.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Ibuprofen reference standards, pharmacopeial and non-pharmacopeial Ibuprofen impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Ibuprofen-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Ibuprofen Impurity 9
Ibuprofen
Ibuprofen Sodium Salt
Ibuprofen Sodium Salt Dihydrate
Ibuprofen EP Impurity A
Ibuprofen EP Impurity B
Ibuprofen Sodium EP Impurity B
Ibuprofen EP Impurity B
Ibuprofen EP Impurity C
Ibuprofen EP Impurity D Sodium Salt
Ibuprofen EP Impurity D
Ibuprofen Impurity E
Ibuprofen EP Impurity F
Ibuprofen EP Impurity G
Ibuprofen EP Impurity H
Ibuprofen EP Impurity I
Ibuprofen EP Impurity J
Ibuprofen EP Impurity K
Ibuprofen EP Impurity L
Ibuprofen EP Impurity M
Ibuprofen EP Impurity N
Ibuprofen EP Impurity N sodium salt
Ibuprofen Impurity O Sodium
Ibuprofen EP Impurity P
Ibuprofen EP Impurity Q
Ibuprofen EP Impurity R
Ibuprofen Impurity 19
Ibuprofen Impurity 20
Ibuprofen Impurity 21
Ibuprofen Impurity 22
Ibuprofen Impurity 23
Ibuprofen Impurity 24
Ibuprofen Impurity 25
Ibuprofen Impurity 26
Ibuprofen Impurity 27
1-Ethyl-4-Isobutylbenzene
Ibuprofen Impurity 13
Ibuprofen Impurity 30
Ibuprofen Impurity 31
Ibuprofen Impurity 32
Ibuprofen Impurity 33
Ibuprofen Impurity 34
Ibuprofen Impurity 36
Ibuprofen Impurity 37
1-(4-Isobutylphenyl)ethanol
4-Isobutylstyrene
Ibuprofen methyl ester
(S)-(+)-Ibuprofen
Ibuprofen PEG 600 Ester Impurity
N-(1-Phenylethyl) Ibuprofen Amide
(R)-(-)-Ibuprofen
(S)-Ibuprofen
Ibuprofen Sorbitol Ester (Mixture of Diastereomers)
Ibuprofen PEG 400 ester impurity
Ibuprofen Piconol Impurity
2-(4-isobutylphenyl)propanal(Ibuprofenal)
2-(4-butylphenyl) Propanal
3-Ethylbenzophenone
Ibuprofen Lysine
Ibuprofen PBA-Amide Impurity
Dexibuprofen Ethyl Ester
Dexibuprofen Propylene Glycol Ester
(S)-Ibuprofen Isopropyl Ester
Dexibuprofen Methyl Ester
Ibuprofen PEG Ester
Ibuprofen PEG monoester Impurity
Ibuprofen Sorbitol
Ibuprofen Acyl-beta-D-glucuronide (Mixture of diastereomers)
Ibuprofen Isopropyl Ester
Dexibuprofen Amide Impurity
Ibuprofen Impurity 2
2-(4-Isopropylphenyl)propanoicacid
4-Carboxy-a-methylbenzeneacetic Acid
Hydratropic Acid
4-isobutylphenol
Ibuprofen Carboxylic Acid
Ibuprofen Impurity 58
2-(1-Chloroethyl)-5,5-dimethyl-2-[4-(2-methylpropyl)phenyl]-1,3-dioxane
Ibuprofen Impurity 28
1,2-dihydroxy Ibuprofen
Ibuprofen Impurity 6
Ibuprofen Ethyl Ester
4-(Isobutyryl)benzoic acid
Hydroxyisobutyl Acetophenone
Ibuprofen Impurity 1
Ibuprofen Impurity 7
Hydroxy Ibuprofen
rac-Ibuprofen Carboxymethyl Ester
(S)-(+)-Ibuprofen Propylene Glycol Ester
(S)-beta-Isopropylphenethylamine
1,2 Dihydroxy Ibuprofen
Dihydroxy Ibuprofen
3-(4-isobutyryl phenyl)but-3-en-2-one
Ibuprofen Ester Impurity (PEG600)
4-Isopropylbenzoic Acid
2-(3-isobutylphenyl)propanal
PEG-Ibuprofen ester
Ibuprofen Sorbitan Ester (Mixture of Isomers)
2-Ethyl-2-(4-isobutylphenyl)-5,5dimethyl-1,3-dioxane
2-(4-Isobutylphenyl)acetic Acid
2-(1,1-dichloroethyl)-2-(4-isobutylphenyl)-5,5-dimethyl-1,3-dioxane
2-(4-Isopropylphenyl)acrylic Acid
Ibuprofen Impurity 22
Ibuprofen Impurity 23
Ibuprofen Impurity 26
1-(4-(sec-Butyl)phenyl)propan-1-one
Ibuprofen EP Impurity O
3-(4-isobutyryl)phenyl butanoic acid
(2S)-2-(4-isobutylphenyl)-7-methyl-6-phenyloctan-3-one
Ibuprofen Sorbitan Ester
Isopropyl 4-Acetylbenzoate
Ibuprofen Impurity 38
Ibuprofen Lysinate
Ibuprofen Arginate
Ibuprofen Impurity 4
Ibuprofen 1,2-Propylene Glycol Esters (Mixture of Regio and Stereoisomers)
Ibuprofen Impurity 8
Ibuprofen Impurity 10
Ibuprofen Impurity 3
Ibuprofen Impurity 5
Ibuprofen Impurity 11
Ibuprofen PEG Diester
Ibuprofen Impurity 12

Isotope Labelled Compounds

Ibuprofen D3
(R)-Ibuprofen-d3
(S)-Ibuprofen-d3
Ibuprofen 13C,D3
Ibuprofen-d4