Hydroxychloroquine Related Compounds & Impurities

Hydroxychloroquine is a 4-aminoquinoline antimalarial with immunomodulatory properties, used for rheumatoid arthritis, systemic lupus erythematosus and malaria prophylaxis.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Hydroxychloroquine reference standards, pharmacopeial and non-pharmacopeial Hydroxychloroquine impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Hydroxychloroquine-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Hydroxychloroquine Sulfate
Hydroxychloroquine Sulfate
  • CAT. No.H090000
  • CAS. No.747-36-4
  • Mol. F.C18H28ClN3O5S
  • Mol. W.433.95 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine
Hydroxychloroquine
  • CAT. No.H090000A
  • CAS. No.118-42-3
  • Mol. F.C18H26ClN3O
  • Mol. W.335.88 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Sulfate EP Impurity C
Hydroxychloroquine Sulfate EP Impurity C
  • CAT. No.H090001
  • CAS. No.4298-15-1
  • Mol. F.C16H22ClN3O
  • Mol. W.307.80 g/mol
  • Stock Status:Instock
Product View
Product Compare
Desethylhydroxychloroquine Dihydrochloride
Desethylhydroxychloroquine Dihydrochloride
  • CAT. No.H090001A
  • CAS. No.NA
  • Mol. F.C16H22ClN3O.2HCl
  • Mol. W.380.74 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine-O-Acetate
Hydroxychloroquine-O-Acetate
  • CAT. No.H090002
  • CAS. No.47493-14-1
  • Mol. F.C20H28ClN3O2
  • Mol. W.377.91 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine N-Oxide Dihydrochloride
Hydroxychloroquine N-Oxide Dihydrochloride
  • CAT. No.H090004
  • CAS. No.1449223-88-4 (free base)
  • Mol. F.C18H26ClN3O2.2HCl
  • Mol. W.424.79 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity A
Hydroxychloroquine Impurity A
  • CAT. No.H090004A
  • CAS. No.1449223-88-4
  • Mol. F.C18H26ClN3O2
  • Mol. W.351.87 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine Impurity I
Hydroxychloroquine Impurity I
  • CAT. No.H090005
  • CAS. No.NA
  • Mol. F.C25H26Cl2N4O
  • Mol. W.469.41 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Dimer
Hydroxychloroquine Dimer
  • CAT. No.H090006
  • CAS. No.2732209-42-4
  • Mol. F.C36H50Cl2N6O
  • Mol. W.653.75 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine O-Sulfate Sodium Salt
Hydroxychloroquine O-Sulfate Sodium Salt
  • CAT. No.H090007
  • CAS. No.NA
  • Mol. F.C18H25ClN3NaO4S
  • Mol. W.437.92 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine O-Sulfate
Hydroxychloroquine O-Sulfate
  • CAT. No.H090007A
  • CAS. No.103152-84-7
  • Mol. F.C18H26ClN3O4S
  • Mol. W.415.93 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine EP Impurity F
Hydroxychloroquine EP Impurity F
  • CAT. No.H090008
  • CAS. No.6281-58-9
  • Mol. F.C14H15ClN2
  • Mol. W.246.74 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine Sulfate EP Impurity D
Hydroxychloroquine Sulfate EP Impurity D
  • CAT. No.H090009
  • CAS. No.1476-52-4
  • Mol. F.C16H22ClN3
  • Mol. W.291.82 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Sulfate EP Impurity E
Hydroxychloroquine Sulfate EP Impurity E
  • CAT. No.H090010
  • CAS. No.10500-64-8
  • Mol. F.C14H17ClN2O
  • Mol. W.264.75 g/mol
  • Stock Status:Instock
Product View
Product Compare
(2-{[4-(7-chloro-quinolin-4-ylamino)pentyl]-ethyl-amino}-ethyl)ester
(2-{[4-(7-chloro-quinolin-4-ylamino)pentyl]-ethyl-amino}-ethyl)ester
  • CAT. No.H090011
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Sulfate EP Impurity B
Hydroxychloroquine Sulfate EP Impurity B
  • CAT. No.H090012
  • CAS. No.103152-84-7
  • Mol. F.C18H26ClN3O4S
  • Mol. W.415.93 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxynovaldiamine
Hydroxynovaldiamine
  • CAT. No.H090014
  • CAS. No.69559-11-1
  • Mol. F.C9H22N2O
  • Mol. W.174.28 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine Impurity 1
Hydroxychloroquine Impurity 1
  • CAT. No.H090015
  • CAS. No.2518282-96-5
  • Mol. F.C25H26Cl2N4
  • Mol. W.453.41 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 2
Hydroxychloroquine Impurity 2
  • CAT. No.H090016
  • CAS. No.NA
  • Mol. F.C18H26ClN3O
  • Mol. W.335.88 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 3
Hydroxychloroquine Impurity 3
  • CAT. No.H090017
  • CAS. No.NA
  • Mol. F.C18H26ClN3O
  • Mol. W.335.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine 3-Bromo Impurity
Hydroxychloroquine 3-Bromo Impurity
  • CAT. No.H090018
  • CAS. No.2054859-08-2
  • Mol. F.C18H25BrClN3O
  • Mol. W.414.77 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Acid
Hydroxychloroquine Acid
  • CAT. No.H090019
  • CAS. No.645406-24-2
  • Mol. F.C18H24ClN3O3
  • Mol. W.365.85 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine R-isomer Impurity
Hydroxychloroquine R-isomer Impurity
  • CAT. No.H090020
  • CAS. No.137433-23-9
  • Mol. F.C18H26ClN3O
  • Mol. W.335.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine S-Isomer
Hydroxychloroquine S-Isomer
  • CAT. No.H090021
  • CAS. No.137433-24-0
  • Mol. F.C18H26ClN3O
  • Mol. W.335.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Desethyl hydrochloroquine-O-Acetate
Desethyl hydrochloroquine-O-Acetate
  • CAT. No.H090022
  • CAS. No.NA
  • Mol. F.C18H24ClN3O2
  • Mol. W.349.86 g/mol
  • Stock Status:Instock
Product View
Product Compare
N-Nitroso Hydroxychloroquine
N-Nitroso Hydroxychloroquine
  • CAT. No.H090023
  • CAS. No.NA
  • Mol. F.C17H22ClN4O2
  • Mol. W.364.87 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Chloroquine Sulfate
Chloroquine Sulfate
  • CAT. No.H090025
  • CAS. No.132-73-0
  • Mol. F.C18H28ClN3O4S
  • Mol. W.417.95 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
5-(ethyl(2-hydroxyethyl)amino)pentan-2-ol
5-(ethyl(2-hydroxyethyl)amino)pentan-2-ol
  • CAT. No.H090026
  • CAS. No.84979-83-9
  • Mol. F.C9H21NO2
  • Mol. W.175.27 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
2-((7-chloroquinolin-4-yl)(ethyl)amino)ethan-1-ol
2-((7-chloroquinolin-4-yl)(ethyl)amino)ethan-1-ol
  • CAT. No.H090027
  • CAS. No.91911-59-0
  • Mol. F.C13H15ClN2O
  • Mol. W.250.72 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine EP Impurity C Hydrochloride
Hydroxychloroquine EP Impurity C Hydrochloride
  • CAT. No.H090028
  • CAS. No.159358-29-9
  • Mol. F.C16H23Cl2N3O
  • Mol. W.344.28 g/mol
  • Stock Status:Limited Stock
Product View
Product Compare
Hydroxychloroquine EP Impurity F Hydrochloride
Hydroxychloroquine EP Impurity F Hydrochloride
  • CAT. No.H090029
  • CAS. No.NA
  • Mol. F.C14H16Cl2N2
  • Mol. W.283.20 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine EP Impurity C
N-Nitroso Hydroxychloroquine EP Impurity C
  • CAT. No.H090031
  • CAS. No.NA
  • Mol. F.C16H21ClN4O2
  • Mol. W.336.82 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 9
Hydroxychloroquine Impurity 9
  • CAT. No.H090032
  • CAS. No.86-47-5
  • Mol. F.C10H6ClNO3
  • Mol. W.223.61 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 18
Hydroxychloroquine Impurity 18
  • CAT. No.H090033
  • CAS. No.NA
  • Mol. F.C16H21ClN2O2
  • Mol. W.308.80 g/mol
  • Stock Status:Instock
Product View
Product Compare
N-N-Dinitroso Hydroxychloroquine EP Impurity C
N-N-Dinitroso Hydroxychloroquine EP Impurity C
  • CAT. No.H090034
  • CAS. No.NA
  • Mol. F.C16H20ClN5O3
  • Mol. W.365.81 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso-Hydroxychloroquine
N-Nitroso-Hydroxychloroquine
  • CAT. No.H090035
  • CAS. No.NA
  • Mol. F.C18H25ClN4O2
  • Mol. W.364.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine Impurity 1
N-Nitroso Hydroxychloroquine Impurity 1
  • CAT. No.H090036
  • CAS. No.NA
  • Mol. F.C16H21ClN4O
  • Mol. W.320.82 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine-O-Acetate
N-Nitroso Hydroxychloroquine-O-Acetate
  • CAT. No.H090037
  • CAS. No.NA
  • Mol. F.C20H27ClN4O3
  • Mol. W.406.91 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine Impurity 2
N-Nitroso Hydroxychloroquine Impurity 2
  • CAT. No.H090038
  • CAS. No.NA
  • Mol. F.C16H20ClN3O3
  • Mol. W.337.80 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine Sulfate EP Impurity B
N-Nitroso Hydroxychloroquine Sulfate EP Impurity B
  • CAT. No.H090039
  • CAS. No.NA
  • Mol. F.C18H25ClN4O5S
  • Mol. W.444.93 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine EP Impurity A
N-Nitroso Hydroxychloroquine EP Impurity A
  • CAT. No.H090040
  • CAS. No.NA
  • Mol. F.C18H25ClN4O3
  • Mol. W.380.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine EP Impurity E
N-Nitroso Hydroxychloroquine EP Impurity E
  • CAT. No.H090041
  • CAS. No.NA
  • Mol. F.C14H16ClN3O2
  • Mol. W.293.75 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine-O-Acetate(Acetic acid)
Hydroxychloroquine-O-Acetate(Acetic acid)
  • CAT. No.H090042
  • CAS. No.47493-14-1 (Free base)
  • Mol. F.C20H28ClN3O2.C2H4O2
  • Mol. W.437.96 g/mol
  • Stock Status:Instock
Product View
Product Compare
(S)-Chloroquine
(S)-Chloroquine
  • CAT. No.H090043
  • CAS. No.58175-86-3
  • Mol. F.C18H26ClN3
  • Mol. W.319.87 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-Nitroso Hydroxychloroquine EP Impurity D
N-Nitroso Hydroxychloroquine EP Impurity D
  • CAT. No.H090044
  • CAS. No.NA
  • Mol. F.C16H21ClN4O
  • Mol. W.320.82 g/mol
  • Stock Status:Instock
Product View
Product Compare
Hydroxychloroquine Impurity 20
Hydroxychloroquine Impurity 20
  • CAT. No.H090045
  • CAS. No.NA
  • Mol. F.C16H21ClN4O2
  • Mol. W.336.82 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 4
Hydroxychloroquine Impurity 4
  • CAT. No.H090046
  • CAS. No.NA
  • Mol. F.C8H20N2O
  • Mol. W.160.26 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 6
Hydroxychloroquine Impurity 6
  • CAT. No.H090047
  • CAS. No.NA
  • Mol. F.C16H21ClN4O5S
  • Mol. W.416.88 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 5
Hydroxychloroquine Impurity 5
  • CAT. No.H090048
  • CAS. No.NA
  • Mol. F.C18H23ClN4O3
  • Mol. W.378.85 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine Impurity 7
Hydroxychloroquine Impurity 7
  • CAT. No.H090049
  • CAS. No.16600-22-9
  • Mol. F.C12H10ClNO3
  • Mol. W.251.70 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
N-N-Dinitroso Hydroxychloroquine EP Impurity D
N-N-Dinitroso Hydroxychloroquine EP Impurity D
  • CAT. No.H090050
  • CAS. No.NA
  • Mol. F.C16H20ClN5O2
  • Mol. W.349.82 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Hydroxychloroquine O-Sulfate sodium
Hydroxychloroquine O-Sulfate sodium
  • CAT. No.H090051
  • CAS. No.2740402-74-6
  • Mol. F.C18H25ClN3O4S.Na
  • Mol. W.437.90 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare

Metabolites

Hydroxychloroquine O-beta-D-glucuronide
Hydroxychloroquine O-beta-D-glucuronide
  • CAT. No.H090030
  • CAS. No.NA
  • Mol. F.C24H34ClN3O7
  • Mol. W.512.00 g/mol
  • Stock Status:Limited Stock
Product View
Product Compare

Isotope Labelled Compounds

Hydroxychloroquine-D4 Sulfate
Hydroxychloroquine-D4 Sulfate
  • CAT. No.H090003
  • CAS. No.1854126-45-6
  • Mol. F.C18H24D4ClN3O5S
  • Mol. W.437.97 g/mol
  • Stock Status:Limited Stock
Product View
Product Compare
Hydroxychloroquine D4 Sulfate
Hydroxychloroquine D4 Sulfate
  • CAT. No.H090003A
  • CAS. No.1216432-56-2
  • Mol. F.C18H22D4ClN3O.H2SO4
  • Mol. W.437.97 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
HYDROXYCHLOROQUINE DIOXALATE SALT
HYDROXYCHLOROQUINE DIOXALATE SALT
  • CAT. No.H090024
  • CAS. No.118-42-3(Unlabelled)
  • Mol. F.C22H25D5ClN3O9
  • Mol. W.520.97 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare