Fluticasone Related Compounds & Impurities

Fluticasone is a potent synthetic corticosteroid with high topical activity and low systemic bioavailability, used in inhaled formulations for asthma and COPD and intranasally for rhinitis.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Fluticasone reference standards, pharmacopeial and non-pharmacopeial Fluticasone impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Fluticasone-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Fluticasone Propionate
Fluticasone Propionate
  • CAT. No.F130000
  • CAS. No.80474-14-2
  • Mol. F.C25H31F3O5S
  • Mol. W.500.57 g/mol
  • Stock Status:Instock
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Fluticasone
Fluticasone
  • CAT. No.F130000B
  • CAS. No.90566-53-3
  • Mol. F.C22H27F3O4S
  • Mol. W.444.51 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone EP Impurity A
Fluticasone EP Impurity A
  • CAT. No.F130001
  • CAS. No.65429-42-7
  • Mol. F.C24H30F2O6
  • Mol. W.452.40 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity B
Fluticasone Propionate EP Impurity B
  • CAT. No.F130002
  • CAS. No.948566-12-9
  • Mol. F.C24H30F2O6S
  • Mol. W.484.55 g/mol
  • Stock Status:Instock
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Fluticasone Furoate EP Impurity B
Fluticasone Furoate EP Impurity B
  • CAT. No.F130003
  • CAS. No.80474-24-4
  • Mol. F.C24H29F3O5S
  • Mol. W.486.50 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity E
Fluticasone Propionate EP Impurity E
  • CAT. No.F130004
  • CAS. No.105613-90-9
  • Mol. F.C25H33F3O5S
  • Mol. W.502.50 g/mol
  • Stock Status:Instock
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Fluticasone EP Impurity F
Fluticasone EP Impurity F
  • CAT. No.F130005
  • CAS. No.1219174-94-3
  • Mol. F.C25H29F3O5S
  • Mol. W.498.50 g/mol
  • Stock Status:Instock
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Fluticasone EP Impurity H
Fluticasone EP Impurity H
  • CAT. No.F130006
  • CAS. No.201812-64-8
  • Mol. F.C48H58F4O10S2
  • Mol. W.935.09 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity I
Fluticasone Propionate EP Impurity I
  • CAT. No.F130007
  • CAS. No.960071-64-1
  • Mol. F.C48H58F4O10S3
  • Mol. W.967.16 g/mol
  • Stock Status:Under Synthesis
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Fluticasone Trioxo Impurity
Fluticasone Trioxo Impurity
  • CAT. No.F130008
  • CAS. No.219719-95-6
  • Mol. F.C22H24F2O5S
  • Mol. W.438.48 g/mol
  • Stock Status:Instock
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Fluticasone Furoate
Fluticasone Furoate
  • CAT. No.F130009
  • CAS. No.397864-44-7
  • Mol. F.C27H29F3O6S
  • Mol. W.538.58 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity D
Fluticasone Propionate EP Impurity D
  • CAT. No.F130010
  • CAS. No.73205-13-7
  • Mol. F.C25H32F2O5S
  • Mol. W.482.58 g/mol
  • Stock Status:Instock
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Fluticasone 17beta-Carboxylic Acid
Fluticasone 17beta-Carboxylic Acid
  • CAT. No.F130013
  • CAS. No.28416-82-2
  • Mol. F.C21H26F2O5
  • Mol. W.396.42 g/mol
  • Stock Status:Instock
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Fluticasone Carbothioic Acid Impurity
Fluticasone Carbothioic Acid Impurity
  • CAT. No.F130014
  • CAS. No.80474-45-9
  • Mol. F.C24H30F2O5S
  • Mol. W.468.55 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity G
Fluticasone Propionate EP Impurity G
  • CAT. No.F130015
  • CAS. No.220589-37-7
  • Mol. F.C43H51F5O8S
  • Mol. W.822.92 g/mol
  • Stock Status:Instock
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Fluticasone Propionate EP Impurity D
Fluticasone Propionate EP Impurity D
  • CAT. No.F130018
  • CAS. No.73205-13-7
  • Mol. F.C25H32F2O5S
  • Mol. W.482.58 g/mol
  • Stock Status:Instock
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Fluticasone Propionate Dithioacid
Fluticasone Propionate Dithioacid
  • CAT. No.F130019
  • CAS. No.NA
  • Mol. F.C24H30F2O4S2
  • Mol. W.484.63 g/mol
  • Stock Status:Custom Synthesis
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Cloticasone Propionate
Cloticasone Propionate
  • CAT. No.F130020
  • CAS. No.80486-69-7
  • Mol. F.C25H31ClF2O5S
  • Mol. W.517.02 g/mol
  • Stock Status:Limited Stock
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Fluticasone Impurity 1
Fluticasone Impurity 1
  • CAT. No.F130022
  • CAS. No.59860-80-9
  • Mol. F.C25H32F2O6
  • Mol. W.466.51 g/mol
  • Stock Status:Limited Stock
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Fluticasone S-methyl Impurity
Fluticasone S-methyl Impurity
  • CAT. No.F130023
  • CAS. No.NA
  • Mol. F.NA
  • Mol. W.NA
  • Stock Status:Custom Synthesis
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Iodofluticasone Propionate
Iodofluticasone Propionate
  • CAT. No.F130027
  • CAS. No.80474-67-5
  • Mol. F.C25H31F2IO5S
  • Mol. W.608.48 g/mol
  • Stock Status:Instock
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Fluticasone Impurity 3
Fluticasone Impurity 3
  • CAT. No.F130028
  • CAS. No.192191-51-8
  • Mol. F.C49H60F4O10S2
  • Mol. W.949.12 g/mol
  • Stock Status:Instock
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S-Methyl Fluticasone Furoate
S-Methyl Fluticasone Furoate
  • CAT. No.F130030
  • CAS. No.397864-58-3
  • Mol. F.C27H30F2O6S
  • Mol. W.520.59 g/mol
  • Stock Status:Limited Stock
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Fluticasone Thioacid Impurity
Fluticasone Thioacid Impurity
  • CAT. No.F130032
  • CAS. No.NA
  • Mol. F.C25H31F3O5S
  • Mol. W.500.57 g/mol
  • Stock Status:Under Synthesis
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Fluticasone 21-Isobutyrate
Fluticasone 21-Isobutyrate
  • CAT. No.F130033
  • CAS. No.1648562-63-3
  • Mol. F.C26H33F3O5S
  • Mol. W.514.64 g/mol
  • Stock Status:Custom Synthesis
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Chloro Fluticasone Furoate
Chloro Fluticasone Furoate
  • CAT. No.F130035
  • CAS. No.1374153-88-4
  • Mol. F.C27H29ClF2O6S
  • Mol. W.555.03 g/mol
  • Stock Status:Instock
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Fluticasone Furoate 1,2 dihydro Impurity
Fluticasone Furoate 1,2 dihydro Impurity
  • CAT. No.F130036
  • CAS. No.398454-98-3
  • Mol. F.C27H31F3O6S
  • Mol. W.540.59 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Furoate Sulfenic Acid Impurity
Fluticasone Furoate Sulfenic Acid Impurity
  • CAT. No.F130037
  • CAS. No.948566-11-8
  • Mol. F.C26H28F2O7S
  • Mol. W.522.56 g/mol
  • Stock Status:Instock
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6-Chloro Fluticasone Priopionate Impurity
6-Chloro Fluticasone Priopionate Impurity
  • CAT. No.F130038
  • CAS. No.NA
  • Mol. F.C25H31ClF2O5S
  • Mol. W.517.03 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Furoate EP Impurity A
Fluticasone Furoate EP Impurity A
  • CAT. No.F130039
  • CAS. No.397864-63-0
  • Mol. F.C26H28F2O7
  • Mol. W.490.49 g/mol
  • Stock Status:Instock
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Fluticasone Furoate EP Impurity E
Fluticasone Furoate EP Impurity E
  • CAT. No.F130040
  • CAS. No.398454-97-2
  • Mol. F.C27H30F2O6S
  • Mol. W.520.59 g/mol
  • Stock Status:Instock
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Fluticasone Furoate EP Impurity L
Fluticasone Furoate EP Impurity L
  • CAT. No.F130041
  • CAS. No.NA
  • Mol. F.C47H52F4O10S2
  • Mol. W.917.03 g/mol
  • Stock Status:Custom Synthesis
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6-Ketofluticasone Propionate
6-Ketofluticasone Propionate
  • CAT. No.F130045
  • CAS. No.NA
  • Mol. F.C25H30F2O6S
  • Mol. W.496.56 g/mol
  • Stock Status:Instock
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Fluticasone O-fluoro methyl Ester
Fluticasone O-fluoro methyl Ester
  • CAT. No.F130046
  • CAS. No.572880-17-2
  • Mol. F.C27H29F3O7
  • Mol. W.522.51 g/mol
  • Stock Status:Under Synthesis
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Fluticasone EP Impurity K
Fluticasone EP Impurity K
  • CAT. No.F130047
  • CAS. No.NA
  • Mol. F.C25H31ClF2O5S
  • Mol. W.517.03 g/mol
  • Stock Status:Instock
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Fluticasone Furoate EP Impurity F
Fluticasone Furoate EP Impurity F
  • CAT. No.F130048
  • CAS. No.NA
  • Mol. F.C29H34F2O7
  • Mol. W.532.57 g/mol
  • Stock Status:Limited Stock
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Fluticasone 11-Keto Impurity
Fluticasone 11-Keto Impurity
  • CAT. No.F130049
  • CAS. No.397864-56-1
  • Mol. F.C27H27F3O6S
  • Mol. W.536.56 g/mol
  • Stock Status:Instock
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Fluticasone Furoate Impurity H
Fluticasone Furoate Impurity H
  • CAT. No.F130050
  • CAS. No.NA
  • Mol. F.C27H29ClF2O6S
  • Mol. W.555.03 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Furoate EP Impurity G
Fluticasone Furoate EP Impurity G
  • CAT. No.F130051
  • CAS. No.785806-96-4
  • Mol. F.C27H29ClF2O6S
  • Mol. W.555.03 g/mol
  • Stock Status:Instock
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Fluticasone Furoate Impurity J
Fluticasone Furoate Impurity J
  • CAT. No.F130052
  • CAS. No.NA
  • Mol. F.C27H28ClF3O6S
  • Mol. W.573.02 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Furoate Impurity I
Fluticasone Furoate Impurity I
  • CAT. No.F130053
  • CAS. No.NA
  • Mol. F.C27H29F3O6S
  • Mol. W.538.58 g/mol
  • Stock Status:Custom Synthesis
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(6S,9R,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate
(6S,9R,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate
  • CAT. No.F130054
  • CAS. No.NA
  • Mol. F.C27H29F3O5S
  • Mol. W.522.58 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 12
Fluticasone Impurity 12
  • CAT. No.F130055
  • CAS. No.80474-13-1
  • Mol. F.C25H32F2O5S
  • Mol. W.482.58 g/mol
  • Stock Status:Custom Synthesis
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N,N-Diethylfuran-2-carboxamide
N,N-Diethylfuran-2-carboxamide
  • CAT. No.F130056
  • CAS. No.32488-17-8
  • Mol. F.C9H13NO2
  • Mol. W.167.21 g/mol
  • Stock Status:Custom Synthesis
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(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic Acid
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthrene-17-carboxylic Acid
  • CAT. No.F130057
  • CAS. No.1687742-59-1
  • Mol. F.C21H30F2O5
  • Mol. W.400.46 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 8
Fluticasone Impurity 8
  • CAT. No.F130058
  • CAS. No.80473-92-3
  • Mol. F.C21H26F2O4S
  • Mol. W.412.49 g/mol
  • Stock Status:Instock
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6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-17-[(iodosulfanyl)carbonyl]-3-oxo-androsta-1,4-diene-17alpha-yl furoate
6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-17-[(iodosulfanyl)carbonyl]-3-oxo-androsta-1,4-diene-17alpha-yl furoate
  • CAT. No.F130059
  • CAS. No.NA
  • Mol. F.C26H27F2IO6S
  • Mol. W.632.46 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 22
Fluticasone Impurity 22
  • CAT. No.F130060
  • CAS. No.709002-84-6
  • Mol. F.C24H31F2NO5S
  • Mol. W.483.57 g/mol
  • Stock Status:Instock
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Fluticasone Impurity 21
Fluticasone Impurity 21
  • CAT. No.F130061
  • CAS. No.22593-10-8
  • Mol. F.C25H32F2O6
  • Mol. W.466.51 g/mol
  • Stock Status:Custom Synthesis
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Diflorasone 21-Propionate
Diflorasone 21-Propionate
  • CAT. No.F130062
  • CAS. No.541502-98-1
  • Mol. F.C25H32F2O6
  • Mol. W.466.51 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 4
Fluticasone Impurity 4
  • CAT. No.F130063
  • CAS. No.105638-31-1
  • Mol. F.C27H35F2NO6S
  • Mol. W.539.60 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Propionate Fluoromethyl Ester Impurity
Fluticasone Propionate Fluoromethyl Ester Impurity
  • CAT. No.F130064
  • CAS. No.1174034-79-7
  • Mol. F.C25H31F3O6
  • Mol. W.484.51 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 25
Fluticasone Impurity 25
  • CAT. No.F130065
  • CAS. No.23961-95-7
  • Mol. F.C22H27FO5
  • Mol. W.390.45 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 29
Fluticasone Impurity 29
  • CAT. No.F130066
  • CAS. No.NA
  • Mol. F.C21H28F2O2S
  • Mol. W.382.51 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 30
Fluticasone Impurity 30
  • CAT. No.F130068
  • CAS. No.NA
  • Mol. F.C22H27FO5
  • Mol. W.390.45 g/mol
  • Stock Status:Instock
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Fluticasone Furoate Impurity 1
Fluticasone Furoate Impurity 1
  • CAT. No.F130069
  • CAS. No.948569-98-0
  • Mol. F.C27H29F3O7S
  • Mol. W.554.58 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone EP Impurity J+K
Fluticasone EP Impurity J+K
  • CAT. No.F130070
  • CAS. No.NA
  • Mol. F.C50H62ClF5O10S2
  • Mol. W.1017.60 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Furoate Trisulphane Impurity
Fluticasone Furoate Trisulphane Impurity
  • CAT. No.F130071
  • CAS. No.NA
  • Mol. F.C53H56F4O11S3
  • Mol. W.1041.19 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 2
Fluticasone Impurity 2
  • CAT. No.F130072
  • CAS. No.NA
  • Mol. F.C42H50F4O8S2
  • Mol. W.822.97 g/mol
  • Stock Status:Instock
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Fluticasone Impurity 5
Fluticasone Impurity 5
  • CAT. No.F130073
  • CAS. No.NA
  • Mol. F.C53H56F4O12S2
  • Mol. W.1025.13 g/mol
  • Stock Status:Custom Synthesis
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Fluticasone Impurity 7
Fluticasone Impurity 7
  • CAT. No.F130074
  • CAS. No.1351451-82-5
  • Mol. F.C26H32F2O7S
  • Mol. W.526.59 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Fluticasone Propionate D3
Fluticasone Propionate D3
  • CAT. No.F130016
  • CAS. No.80474-14-2(Unlabeled)
  • Mol. F.C25H28D3F3O5S
  • Mol. W.503.59 g/mol
  • Stock Status:Instock
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Fluticasone propionate-D5
Fluticasone propionate-D5
  • CAT. No.F130017
  • CAS. No.1093258-28-6
  • Mol. F.C25H26D5F3O5S
  • Mol. W.505.61 g/mol
  • Stock Status:Under Synthesis
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Fluticasone Furoate D3
Fluticasone Furoate D3
  • CAT. No.F130043
  • CAS. No.397864-44-7(unlabelled)
  • Mol. F.C27H26D3F3O6S
  • Mol. W.541.59 g/mol
  • Stock Status:Under Synthesis
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Fluticasone Furoate D5
Fluticasone Furoate D5
  • CAT. No.F130067
  • CAS. No.397864-44-7 (Unlabelled)
  • Mol. F.C27H24D5F3O6S
  • Mol. W.543.61 g/mol
  • Stock Status:Custom Synthesis
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