Encorafenib Related Compounds & Impurities

Encorafenib is a selective BRAF kinase inhibitor used in combination with binimetinib for BRAF V600E/K-mutant melanoma and with cetuximab for BRAF V600E-mutant colorectal cancer.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Encorafenib reference standards, pharmacopeial and non-pharmacopeial Encorafenib impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Encorafenib-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Encorafenib
Encorafenib
  • CAT. No.E1140000
  • CAS. No.1269440-17-6
  • Mol. F.C22H27ClFN7O4S
  • Mol. W.540.00 g/mol
  • Stock Status:Instock
Product View
Product Compare
Encorafenib Impurity 1
Encorafenib Impurity 1
  • CAT. No.E1140002
  • CAS. No.1269440-54-1
  • Mol. F.C10H12IN5
  • Mol. W.329.10 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 2
Encorafenib Impurity 2
  • CAT. No.E1140003
  • CAS. No.1269440-49-4
  • Mol. F.C8H11IN2O
  • Mol. W.278.10 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 3
Encorafenib Impurity 3
  • CAT. No.E1140004
  • CAS. No.1269440-51-8
  • Mol. F.C11H16IN3O
  • Mol. W.333.20 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 4
Encorafenib Impurity 4
  • CAT. No.E1140005
  • CAS. No.19777-66-3
  • Mol. F.C3H10N2.2HCl
  • Mol. W.81.42 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 5
Encorafenib Impurity 5
  • CAT. No.E1140006
  • CAS. No.934660-64-7
  • Mol. F.C11H16N2O2
  • Mol. W.208.30 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 6
Encorafenib Impurity 6
  • CAT. No.E1140007
  • CAS. No.1229025-68-6
  • Mol. F.C13H18N2O4
  • Mol. W.266.30 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 7
Encorafenib Impurity 7
  • CAT. No.E1140008
  • CAS. No.1269232-94-1
  • Mol. F.C11H12BrClFNO2
  • Mol. W.324.60 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 8
Encorafenib Impurity 8
  • CAT. No.E1140009
  • CAS. No.1269232-93-0
  • Mol. F.C7H3BrClFO2
  • Mol. W.253.45 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib R Isomer
Encorafenib R Isomer
  • CAT. No.E1140010
  • CAS. No.1269440-29-0
  • Mol. F.C22H27ClFN7O4S
  • Mol. W.540.01 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity
Encorafenib Nitroso Impurity
  • CAT. No.E1140011
  • CAS. No.NA
  • Mol. F.C22H26ClFN8O5S
  • Mol. W.569.01 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 1
Encorafenib Nitroso Impurity 1
  • CAT. No.E1140012
  • CAS. No.NA
  • Mol. F.C15H20IN7O3
  • Mol. W.473.27 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 2
Encorafenib Nitroso Impurity 2
  • CAT. No.E1140013
  • CAS. No.NA
  • Mol. F.C12H14IN7O3
  • Mol. W.431.19 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 3
Encorafenib Nitroso Impurity 3
  • CAT. No.E1140014
  • CAS. No.NA
  • Mol. F.C12H13IN8O4
  • Mol. W.460.19 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 4
Encorafenib Nitroso Impurity 4
  • CAT. No.E1140015
  • CAS. No.NA
  • Mol. F.C26H32ClFN8O5
  • Mol. W.591.00 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 5
Encorafenib Nitroso Impurity 5
  • CAT. No.E1140016
  • CAS. No.NA
  • Mol. F.C23H26ClFN8O5
  • Mol. W.548.95 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 6
Encorafenib Nitroso Impurity 6
  • CAT. No.E1140017
  • CAS. No.NA
  • Mol. F.C23H25ClFN9O6
  • Mol. W.577.95 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 7
Encorafenib Nitroso Impurity 7
  • CAT. No.E1140018
  • CAS. No.NA
  • Mol. F.C21H24ClFN8O3
  • Mol. W.490.92 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 8
Encorafenib Nitroso Impurity 8
  • CAT. No.E1140019
  • CAS. No.NA
  • Mol. F.C18H18ClFN8O3
  • Mol. W.448.84 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 9
Encorafenib Nitroso Impurity 9
  • CAT. No.E1140020
  • CAS. No.NA
  • Mol. F.C18H17ClFN9O4
  • Mol. W.477.84 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 10
Encorafenib Nitroso Impurity 10
  • CAT. No.E1140021
  • CAS. No.NA
  • Mol. F.C23H28ClFN8O7S2
  • Mol. W.647.10 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 11
Encorafenib Nitroso Impurity 11
  • CAT. No.E1140022
  • CAS. No.NA
  • Mol. F.C23H27ClFN9O6S
  • Mol. W.612.03 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 11
Encorafenib Nitroso Impurity 11
  • CAT. No.E1140023
  • CAS. No.NA
  • Mol. F.C19H20ClFN8O5S
  • Mol. W.526.93 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Nitroso Impurity 12
Encorafenib Nitroso Impurity 12
  • CAT. No.E1140024
  • CAS. No.NA
  • Mol. F.C19H19ClFN9O6S
  • Mol. W.555.93 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Amino Carbamate Impurity
Encorafenib Amino Carbamate Impurity
  • CAT. No.E1140025
  • CAS. No.1269440-78-9
  • Mol. F.C21H25ClFN7O2
  • Mol. W.461.92 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Disulfonamide Impurity
Encorafenib Disulfonamide Impurity
  • CAT. No.E1140027
  • CAS. No.1269440-99-4
  • Mol. F.C23H29ClFN7O6S2
  • Mol. W.618.10 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 9
Encorafenib Impurity 9
  • CAT. No.E1140028
  • CAS. No.NA
  • Mol. F.C11H14BClFNO4
  • Mol. W.289.50 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Impurity 10
Encorafenib Impurity 10
  • CAT. No.E1140029
  • CAS. No.NA
  • Mol. F.C22H24Cl2F2N2O4
  • Mol. W.489.34 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib Descarbamate Impurity
Encorafenib Descarbamate Impurity
  • CAT. No.E1140030
  • CAS. No.3047752-81-5
  • Mol. F.C20H25ClFN7O2S
  • Mol. W.482.00 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare
Encorafenib N-Oxide Impurity
Encorafenib N-Oxide Impurity
  • CAT. No.E1140031
  • CAS. No.NA
  • Mol. F.C22H27ClFN7O5S
  • Mol. W.556.00 g/mol
  • Stock Status:Custom Synthesis
Product View
Product Compare

Metabolites

Metabolite of Encorafenib
Metabolite of Encorafenib
  • CAT. No.E1140026
  • CAS. No.NA
  • Mol. F.C17H18ClFN6O2S
  • Mol. W.424.88 g/mol
  • Stock Status:Please Enquire
Product View
Product Compare

Isotope Labelled Compounds

Encorafenib 13CD3
Encorafenib 13CD3
  • CAT. No.E1140001
  • CAS. No.1269440-17-6(Unlabeled)
  • Mol. F.C2113CH24D3ClFN7O4S
  • Mol. W.544.02 g/mol
  • Stock Status:Under Synthesis
Product View
Product Compare