Edoxaban Related Compounds & Impurities

Edoxaban is a direct oral factor Xa inhibitor anticoagulant used for stroke prevention in atrial fibrillation and treatment of venous thromboembolism.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Edoxaban reference standards, pharmacopeial and non-pharmacopeial Edoxaban impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Edoxaban-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

N-Nitroso Edoxaban Impurity 1
N-Nitroso Edoxaban Impurity 1
  • CAT. No.E5900101
  • CAS. No.NA
  • Mol. F.C6H8N4OS
  • Mol. W.184.22 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Edoxaban Impurity 2
N-Nitroso Edoxaban Impurity 2
  • CAT. No.E5900102
  • CAS. No.NA
  • Mol. F.C6H7N3OS
  • Mol. W.169.20 g/mol
  • Stock Status:Instock
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N-Nitroso Edoxaban Impurity 4
N-Nitroso Edoxaban Impurity 4
  • CAT. No.E5900103
  • CAS. No.NA
  • Mol. F.C6H6BrN3OS
  • Mol. W.248.10 g/mol
  • Stock Status:Instock
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N-Nitroso Edoxaban Impurity 5
N-Nitroso Edoxaban Impurity 5
  • CAT. No.E5900104
  • CAS. No.NA
  • Mol. F.C7H7N3O3S
  • Mol. W.213.21 g/mol
  • Stock Status:Instock
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N-Nitroso Edoxaban Impurity 3
N-Nitroso Edoxaban Impurity 3
  • CAT. No.E5900105
  • CAS. No.NA
  • Mol. F.C8H9N3O3S
  • Mol. W.227.24 g/mol
  • Stock Status:Instock
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N-Nitroso Edoxaban Desmethyl Impurity 1
N-Nitroso Edoxaban Desmethyl Impurity 1
  • CAT. No.E5900106
  • CAS. No.NA
  • Mol. F.C23H27ClN8O5S
  • Mol. W.563.03 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 104
Edoxaban Impurity 104
  • CAT. No.E5900107
  • CAS. No.1093351-29-1
  • Mol. F.C24H29ClN6O5S
  • Mol. W.549.04 g/mol
  • Stock Status:Custom Synthesis
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N1-(5-bromopyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
N1-(5-bromopyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
  • CAT. No.E5900108
  • CAS. No.NA
  • Mol. F.C24H30BrN7O4S
  • Mol. W.592.51 g/mol
  • Stock Status:Custom Synthesis
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2-(((1S,3R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid
2-(((1S,3R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid
  • CAT. No.E5900109
  • CAS. No.NA
  • Mol. F.C19H27N5O5S
  • Mol. W.437.51 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Bromo tosyl Impurity
Edoxaban Bromo tosyl Impurity
  • CAT. No.E5900110
  • CAS. No.852291-42-0
  • Mol. F.C14H17BrN2O3S2
  • Mol. W.405.33 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity
Edoxaban Impurity
  • CAT. No.E5900111
  • CAS. No.480450-86-0
  • Mol. F.C19H27N5O5SLi
  • Mol. W.444.46 g/mol
  • Stock Status:Instock
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Edoxaban Methyl Impurity Iodide
Edoxaban Methyl Impurity Iodide
  • CAT. No.E5900112
  • CAS. No.NA
  • Mol. F.C25H33ClN7O4S.I
  • Mol. W.690.00 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity H (SSR isomer) (benzene sulfonate salt)
Edoxaban Impurity H (SSR isomer) (benzene sulfonate salt)
  • CAT. No.E5900113
  • CAS. No.NA
  • Mol. F.C30H36ClN7O7S2
  • Mol. W.706.23 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Isomer 4 ( benzene sulfonate salt )
Edoxaban Isomer 4 ( benzene sulfonate salt )
  • CAT. No.E5900114
  • CAS. No.NA
  • Mol. F.C30H36ClN7O7S2
  • Mol. W.706.23 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 103
Edoxaban Impurity 103
  • CAT. No.E5900115
  • CAS. No.480450-85-9
  • Mol. F.C21H31N5O5S
  • Mol. W.465.57 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 74
Edoxaban Impurity 74
  • CAT. No.E5900116
  • CAS. No.365998-35-2
  • Mol. F.C22H33N3O5
  • Mol. W.419.52 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 113
Edoxaban Impurity 113
  • CAT. No.E5900117
  • CAS. No.NA
  • Mol. F.C20H29N5O5S
  • Mol. W.451.54 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 116
Edoxaban Impurity 116
  • CAT. No.E5900118
  • CAS. No.NA
  • Mol. F.C24H32ClN7O4S
  • Mol. W.550.07 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 117
Edoxaban Impurity 117
  • CAT. No.E5900119
  • CAS. No.41374-72-5
  • Mol. F.C9H10N2O3
  • Mol. W.194.19 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 25 (1R,2S,4R) Oxalate
Edoxaban Impurity 25 (1R,2S,4R) Oxalate
  • CAT. No.E590048
  • CAS. No.2605225-72-5
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 33
Edoxaban Impurity 33
  • CAT. No.E590067
  • CAS. No.1243308-37-3
  • Mol. F.C9H10Cl2N2O3
  • Mol. W.264.01 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 79
Edoxaban Impurity 79
  • CAT. No.E590071
  • CAS. No.4755-77-5
  • Mol. F.C4H5ClO3
  • Mol. W.136.53 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 34
Edoxaban Impurity 34
  • CAT. No.E590072
  • CAS. No.1445-73-4
  • Mol. F.C6H11NO
  • Mol. W.113.16 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 77
Edoxaban Impurity 77
  • CAT. No.E590073
  • CAS. No.365997-36-0
  • Mol. F.C15H27NO7S
  • Mol. W.365.44 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Bromo Impurity
Edoxaban Bromo Impurity
  • CAT. No.E590074
  • CAS. No.775280-48-3
  • Mol. F.C24H30BrN7O4S
  • Mol. W.592.50 g/mol
  • Stock Status:Custom Synthesis
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5S-tert-Butyl Edoxaban
5S-tert-Butyl Edoxaban
  • CAT. No.E590075
  • CAS. No.2024614-15-9
  • Mol. F.C21H30ClN5O5
  • Mol. W.467.95 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 55
Edoxaban Impurity 55
  • CAT. No.E590077
  • CAS. No.740794-83-6
  • Mol. F.C23H28ClN7O4S
  • Mol. W.534.03 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 12
Edoxaban Impurity 12
  • CAT. No.E590078
  • CAS. No.1353893-26-1
  • Mol. F.C14H27N3O3.C2H2O4.H2O
  • Mol. W.393.43 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Desmethyl Impurity
Edoxaban Desmethyl Impurity
  • CAT. No.E590079
  • CAS. No.480449-52-3
  • Mol. F.C23H29Cl2N7O4S
  • Mol. W.570.49 g/mol
  • Stock Status:Custom Synthesis
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N1,N2-bis(5-chloropyridin-2-yl)oxalamide dihydrochloride
N1,N2-bis(5-chloropyridin-2-yl)oxalamide dihydrochloride
  • CAT. No.E590080
  • CAS. No.NA
  • Mol. F.C12H10Cl4N4O2
  • Mol. W.384.05g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Isomer 3 p-Toluenesulfonate Salt
Edoxaban Isomer 3 p-Toluenesulfonate Salt
  • CAT. No.E590081
  • CAS. No.1255529-24-8(freebase)
  • Mol. F.C31H38ClN7O7S2
  • Mol. W.720.26 g/mol
  • Stock Status:Under Synthesis
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Edoxaban Tosylate SSS Isomer Tosylate Salt
Edoxaban Tosylate SSS Isomer Tosylate Salt
  • CAT. No.E590082
  • CAS. No.1255529-27-1(FreeBase)
  • Mol. F.C31H38ClN7O7S2
  • Mol. W.720.26 g/mol
  • Stock Status:Limited Stock
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4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
  • CAT. No.E590091
  • CAS. No.165948-23-2
  • Mol. F.C6H8N2S
  • Mol. W.140.21 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 98
Edoxaban Impurity 98
  • CAT. No.E590092
  • CAS. No.365997-32-6
  • Mol. F.C9H15N3O3
  • Mol. W.213.23 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 99
Edoxaban Impurity 99
  • CAT. No.E590093
  • CAS. No.365997-67-7
  • Mol. F.C12H20N4O4
  • Mol. W.284.31 g/mol
  • Stock Status:Custom Synthesis
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tert-Butyl-(1R,2R,5S)-2-amino Edoxaban Oxalate
tert-Butyl-(1R,2R,5S)-2-amino Edoxaban Oxalate
  • CAT. No.E590094
  • CAS. No.1928729-31-0
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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tert-butyl[(1R,2R,5R)-2amino-5-[((dimethylamino)carbomyl)]-cyclohexyl]carbamate oxalate
tert-butyl[(1R,2R,5R)-2amino-5-[((dimethylamino)carbomyl)]-cyclohexyl]carbamate oxalate
  • CAT. No.E590095
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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tert-Butyl-(1S,2S,5S)-2-amino Edoxaban Oxalate
tert-Butyl-(1S,2S,5S)-2-amino Edoxaban Oxalate
  • CAT. No.E590096
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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tert-butyl(1S,2R,5S)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate salt
tert-butyl(1S,2R,5S)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate salt
  • CAT. No.E590097
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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Carbamicacid,N-[(1R,2R,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-,1,1-dimethylethyl ester oxalate salt
Carbamicacid,N-[(1R,2R,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-,1,1-dimethylethyl ester oxalate salt
  • CAT. No.E590098
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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tert-butyl(1S,2S,5R)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate salt
tert-butyl(1S,2S,5R)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate salt
  • CAT. No.E590099
  • CAS. No.2605225-78-1
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 4-methylbenzenesulfonate
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 4-methylbenzenesulfonate
  • CAT. No.E590120
  • CAS. No.852291-40-8
  • Mol. F.C14H18N2O3S2
  • Mol. W.326.43 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban (SSS)-Isomer Besylate Salt
Edoxaban (SSS)-Isomer Besylate Salt
  • CAT. No.E590121
  • CAS. No.1255529-27-1 (Free base)
  • Mol. F.C25H34ClN7O7S2
  • Mol. W.644.16 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban (RRR)-Isomer BesylateSalt
Edoxaban (RRR)-Isomer BesylateSalt
  • CAT. No.E590122
  • CAS. No.1255529-24-8 (Free base)
  • Mol. F.C25H34ClN7O7S2
  • Mol. W.644.16 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban (RSS)-Isomer Besylate Salt
Edoxaban (RSS)-Isomer Besylate Salt
  • CAT. No.E590123
  • CAS. No.1255529-25-9 (Free base)
  • Mol. F.C25H34ClN7O7S2
  • Mol. W.644.16 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban (RRS)- Isomer Besylate Salt
Edoxaban (RRS)- Isomer Besylate Salt
  • CAT. No.E590124
  • CAS. No.500572-10-1 (Free base)
  • Mol. F.C25H34ClN7O7S2
  • Mol. W.644.16 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 120
Edoxaban Impurity 120
  • CAT. No.E590125
  • CAS. No.480449-84-1
  • Mol. F.C14H26N2O4
  • Mol. W.286.40 g/mol
  • Stock Status:Instock
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Edoxaban Impurity 121
Edoxaban Impurity 121
  • CAT. No.E590126
  • CAS. No.2111181-37-2
  • Mol. F.C14H24N2O4
  • Mol. W.284.40 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 84
Edoxaban Impurity 84
  • CAT. No.E590127
  • CAS. No.2760449-95-2
  • Mol. F.C9H19N3O
  • Mol. W.185.27 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 109
Edoxaban Impurity 109
  • CAT. No.E590128
  • CAS. No.1190987-12-2
  • Mol. F.C7H8N2O2S
  • Mol. W.184.20 g/mol
  • Stock Status:Custom Synthesis
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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid,Lithium Salt
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid,Lithium Salt
  • CAT. No.E590129
  • CAS. No.259809-25-1
  • Mol. F.C8H10LiN2O2S
  • Mol. W.205.18 g/mol
  • Stock Status:Custom Synthesis
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N1-(5-chloropyridin-2-yl)-N2-((1S,2R,5S)-5-(dimethylcarbamoyl)-2-(5-methyl-1,2,4,5,6,7-hexahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl) oxalamide
N1-(5-chloropyridin-2-yl)-N2-((1S,2R,5S)-5-(dimethylcarbamoyl)-2-(5-methyl-1,2,4,5,6,7-hexahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl) oxalamide
  • CAT. No.E590130
  • CAS. No.NA
  • Mol. F.C24H32ClN7O4S
  • Mol. W.550.07 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 127
Edoxaban Impurity 127
  • CAT. No.E590131
  • CAS. No.NA
  • Mol. F.C14H27N3O3
  • Mol. W.285.38 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 126
Edoxaban Impurity 126
  • CAT. No.E590132
  • CAS. No.NA
  • Mol. F.C14H27N3O3
  • Mol. W.285.38 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 123 Oxalate
Edoxaban Impurity 123 Oxalate
  • CAT. No.E590133
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 122 Oxalate
Edoxaban Impurity 122 Oxalate
  • CAT. No.E590134
  • CAS. No.NA
  • Mol. F.C16H29N3O7
  • Mol. W.375.42 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 124
Edoxaban Impurity 124
  • CAT. No.E590135
  • CAS. No.2230882-27-4
  • Mol. F.C14H27N3O3
  • Mol. W.285.38 g/mol
  • Stock Status:Custom Synthesis
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Tert-butyl((1R,2S,4R)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)carbamate
Tert-butyl((1R,2S,4R)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)carbamate
  • CAT. No.E590136
  • CAS. No.NA
  • Mol. F.C14H27N3O3
  • Mol. W.285.38 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 71 Hydrochloride
Edoxaban Impurity 71 Hydrochloride
  • CAT. No.E590137
  • CAS. No.1241725-84-7
  • Mol. F.C6H9ClN2S
  • Mol. W.176.67 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 54 Hydrochloride
Edoxaban Impurity 54 Hydrochloride
  • CAT. No.E590140
  • CAS. No.482375-18-8
  • Mol. F.C16H22ClN5O3.HCl
  • Mol. W.404.29 g/mol
  • Stock Status:Under Synthesis
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Edoxaban N-Glucuronide
Edoxaban N-Glucuronide
  • CAT. No.E590141
  • CAS. No.NA
  • Mol. F.C30H38ClN7O10S
  • Mol. W.724.18 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 132
Edoxaban Impurity 132
  • CAT. No.E590142
  • CAS. No.1392745-22-0
  • Mol. F.C14H25NO5
  • Mol. W.287.40 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 134
Edoxaban Impurity 134
  • CAT. No.E590143
  • CAS. No.NA
  • Mol. F.C25H32ClN7O4S
  • Mol. W.562.08 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 133
Edoxaban Impurity 133
  • CAT. No.E590144
  • CAS. No.1541782-99-3
  • Mol. F.C9H12N2O2S
  • Mol. W.212.27 g/mol
  • Stock Status:Custom Synthesis
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Edoxaban Impurity 148
Edoxaban Impurity 148
  • CAT. No.E590204
  • CAS. No.1781640-92-3
  • Mol. F.C6H9N3S
  • Mol. W.155.22 g/mol
  • Stock Status:Custom Synthesis
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