Droxidopa Related Compounds & Impurities

Droxidopa is a synthetic amino acid prodrug converted to noradrenaline, used for neurogenic orthostatic hypotension in autonomic failure.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Droxidopa reference standards, pharmacopeial and non-pharmacopeial Droxidopa impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Droxidopa-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Droxidopa
Droxidopa
  • CAT. No.D870000
  • CAS. No.23651-95-8
  • Mol. F.C9H11NO5
  • Mol. W.213.19 g/mol
  • Stock Status:Instock
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Droxidopa Impurity 1
Droxidopa Impurity 1
  • CAT. No.D870001
  • CAS. No.13023-73-9
  • Mol. F.C8H8O4
  • Mol. W.168.15 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Impurity 18
Droxidopa Impurity 18
  • CAT. No.D870002
  • CAS. No.78603-91-5
  • Mol. F.C15H17NO
  • Mol. W.227.30 g/mol
  • Stock Status:Instock
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Droxidopa Amine
Droxidopa Amine
  • CAT. No.D870005
  • CAS. No.55637-52-0
  • Mol. F.C23H23NO5
  • Mol. W.393.43 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Impurity 10
Droxidopa Impurity 10
  • CAT. No.D870006
  • CAS. No.3916-18-5
  • Mol. F.C9H11NO5
  • Mol. W.213.19 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Racemic Standard
Droxidopa Racemic Standard
  • CAT. No.D870008
  • CAS. No.492-46-6
  • Mol. F.C9H11NO5
  • Mol. W.213.19 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Erythro Isomer
Droxidopa Erythro Isomer
  • CAT. No.D870009
  • CAS. No.16322-99-9
  • Mol. F.C9H11NO5
  • Mol. W.213.19 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Impurity 22
Droxidopa Impurity 22
  • CAT. No.D870011
  • CAS. No.56672-56-1
  • Mol. F.C10H11NO5
  • Mol. W.225.20 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Metabolite Hydrate
Droxidopa Metabolite Hydrate
  • CAT. No.D870012
  • CAS. No.39846-91-8 (free base)
  • Mol. F.C10H13NO5.H2O
  • Mol. W.245.23 g/mol
  • Stock Status:Instock
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(Z)-3-(benzo[d][1,3]dioxol-5-yl)-2-(1,3-dioxoisoindolin-2-yl)acrylic acid
(Z)-3-(benzo[d][1,3]dioxol-5-yl)-2-(1,3-dioxoisoindolin-2-yl)acrylic acid
  • CAT. No.D870013
  • CAS. No.NA
  • Mol. F.C18H11NO6
  • Mol. W.337.29 g/mol
  • Stock Status:Custom Synthesis
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(Z)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)isoindoline-1,3-dione
(Z)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)isoindoline-1,3-dione
  • CAT. No.D870014
  • CAS. No.NA
  • Mol. F.C17H11NO4
  • Mol. W.293.28 g/mol
  • Stock Status:Custom Synthesis
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(Z)-3-(3,4-dihydroxyphenyl)-2-(1,3-dioxoisoindolin-2-yl)acrylic acid
(Z)-3-(3,4-dihydroxyphenyl)-2-(1,3-dioxoisoindolin-2-yl)acrylic acid
  • CAT. No.D870015
  • CAS. No.NA
  • Mol. F.C17H11NO6
  • Mol. W.325.28 g/mol
  • Stock Status:Custom Synthesis
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(Z)-2-(3,4-dihydroxystyryl)isoindoline-1,3-dione
(Z)-2-(3,4-dihydroxystyryl)isoindoline-1,3-dione
  • CAT. No.D870016
  • CAS. No.NA
  • Mol. F.C16H11NO4
  • Mol. W.281.27 g/mol
  • Stock Status:Custom Synthesis
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(2S,3R)-3-(benzo[d][1,3]dioxol-5-yl)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxypropanoic (2S,3S)-4-(3,4-dihydroxyphenyl)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxybutanoic anhydride
(2S,3R)-3-(benzo[d][1,3]dioxol-5-yl)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxypropanoic (2S,3S)-4-(3,4-dihydroxyphenyl)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxybutanoic anhydride
  • CAT. No.D870017
  • CAS. No.NA
  • Mol. F.C36H26N2O13
  • Mol. W.694.61 g/mol
  • Stock Status:Custom Synthesis
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(2S,3R)-2-amino-3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxypropanoic(2S,3S)-2-amino-4-(3,4-dihydroxyphenyl)-3-hydroxybutanoic anhydride
(2S,3R)-2-amino-3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxypropanoic(2S,3S)-2-amino-4-(3,4-dihydroxyphenyl)-3-hydroxybutanoic anhydride
  • CAT. No.D870018
  • CAS. No.NA
  • Mol. F.C20H22N2O9
  • Mol. W.434.41 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Impurity 6
Droxidopa Impurity 6
  • CAT. No.D870019
  • CAS. No.90044-46-5
  • Mol. F.C16H15NO4
  • Mol. W.285.29 g/mol
  • Stock Status:Custom Synthesis
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(2R,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
(2R,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
  • CAT. No.D870020
  • CAS. No.51829-98-2
  • Mol. F.C9H11NO5
  • Mol. W.213.19 g/mol
  • Stock Status:Custom Synthesis
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2,3,8,9-tetrahydroxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-5-carboxylic acid
2,3,8,9-tetrahydroxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-5-carboxylic acid
  • CAT. No.D870021
  • CAS. No.NA
  • Mol. F.C17H15NO6
  • Mol. W.329.30 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa NNC Impurity
Droxidopa NNC Impurity
  • CAT. No.D870022
  • CAS. No.NA
  • Mol. F.C27H26ClN3O3
  • Mol. W.475.97 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa BBC Impurity
Droxidopa BBC Impurity
  • CAT. No.D870023
  • CAS. No.1021462-91-8
  • Mol. F.C25H23ClN2O2.HCl
  • Mol. W.455.38 g/mol
  • Stock Status:Instock
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Droxidopa Impurity 25
Droxidopa Impurity 25
  • CAT. No.D870024
  • CAS. No.106887-48-3
  • Mol. F.C23H23NO5
  • Mol. W.393.43 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa carbamate
Droxidopa carbamate
  • CAT. No.D870026
  • CAS. No.55382-14-4
  • Mol. F.C31H29NO7
  • Mol. W.527.56 g/mol
  • Stock Status:Limited Stock
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Droxidopa Enantiomer Impurity
Droxidopa Enantiomer Impurity
  • CAT. No.D870027
  • CAS. No.51829-99-3(Base)
  • Mol. F.C9H12ClNO5
  • Mol. W.249.65 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Phthalimido Impurity
Droxidopa Phthalimido Impurity
  • CAT. No.D870028
  • CAS. No.NA
  • Mol. F.C17H13NO7
  • Mol. W.343.29 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Impurity 30
Droxidopa Impurity 30
  • CAT. No.D870029
  • CAS. No.92-89-7
  • Mol. F.C13H9NO4
  • Mol. W.243.22 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Dimer Impurity 1
Droxidopa Dimer Impurity 1
  • CAT. No.D870030
  • CAS. No.NA
  • Mol. F.C16H15NO4.HCl
  • Mol. W.321.76 g/mol
  • Stock Status:Custom Synthesis
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Droxidopa Dimer acid Impurity 2
Droxidopa Dimer acid Impurity 2
  • CAT. No.D870031
  • CAS. No.NA
  • Mol. F.C17H15NO6.HCl
  • Mol. W.365.77 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Droxidopa-D3 Sodium Salt
Droxidopa-D3 Sodium Salt
  • CAT. No.D870003
  • CAS. No.NA
  • Mol. F.C9H7D3NO5Na
  • Mol. W.238.20 g/mol
  • Stock Status:Under Synthesis
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Droxidopa Trifluoroacetic Salt 13C7
Droxidopa Trifluoroacetic Salt 13C7
  • CAT. No.D870004
  • CAS. No.Freebase1261397-37-8
  • Mol. F.C213C7H11NO5.C2HF3O2
  • Mol. W.334.16 g/mol
  • Stock Status:Custom Synthesis
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