Domperidone Related Compounds & Impurities

Domperidone is a peripheral dopamine D2-receptor antagonist prokinetic and antiemetic that does not readily cross the blood-brain barrier, used for nausea and gastroparesis.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Domperidone reference standards, pharmacopeial and non-pharmacopeial Domperidone impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Domperidone-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Domperidone
Domperidone
  • CAT. No.D090000
  • CAS. No.57808-66-9
  • Mol. F.C22H24ClN5O2
  • Mol. W.425.91 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity A
Domperidone EP Impurity A
  • CAT. No.D090001
  • CAS. No.53786-28-0
  • Mol. F.C12H14ClN3O
  • Mol. W.251.71 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity B
Domperidone EP Impurity B
  • CAT. No.D090002
  • CAS. No.1346598-11-5
  • Mol. F.C13H14ClN3O2
  • Mol. W.279.72 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity C
Domperidone EP Impurity C
  • CAT. No.D090003
  • CAS. No.118435-03-3
  • Mol. F.C22H24ClN5O3
  • Mol. W.441.91 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity D
Domperidone EP Impurity D
  • CAT. No.D090004
  • CAS. No.1614255-34-3
  • Mol. F.C32H34ClN7O3
  • Mol. W.600.11 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity E
Domperidone EP Impurity E
  • CAT. No.D090005
  • CAS. No.1346602-50-3
  • Mol. F.C32H34ClN7O3
  • Mol. W.600.11 g/mol
  • Stock Status:Instock
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Domperidone EP Impurity F
Domperidone EP Impurity F
  • CAT. No.D090006
  • CAS. No.1391053-55-6
  • Mol. F.C37H42Cl2N8O3
  • Mol. W.717.79 g/mol
  • Stock Status:Instock
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Domperidone Maleate
Domperidone Maleate
  • CAT. No.D090008
  • CAS. No.83898-65-1
  • Mol. F.C22H24ClN5O2.C4H4O4
  • Mol. W.541.98 g/mol
  • Stock Status:Instock
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Domperidone Impurity 1
Domperidone Impurity 1
  • CAT. No.D090009
  • CAS. No.62780-89-6
  • Mol. F.C10H11ClN2O
  • Mol. W.210.66 g/mol
  • Stock Status:Instock
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1-propyl-1,3-dihydro-2H-benzimidazol-2-one
1-propyl-1,3-dihydro-2H-benzimidazol-2-one
  • CAT. No.D090010
  • CAS. No.NA
  • Mol. F.C10H12N2O
  • Mol. W.176.22 g/mol
  • Stock Status:Custom Synthesis
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N-(4-chloro-2-nitrophenyl)piperidin-4-amine hydrate
N-(4-chloro-2-nitrophenyl)piperidin-4-amine hydrate
  • CAT. No.D090011
  • CAS. No.NA
  • Mol. F.C11H16ClN3O3
  • Mol. W.273.72 g/mol
  • Stock Status:Custom Synthesis
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1,3-dihydro-1-(3-hydroxypropenyl)-2H- benzimidazol-2-one monohydrate
1,3-dihydro-1-(3-hydroxypropenyl)-2H- benzimidazol-2-one monohydrate
  • CAT. No.D090012
  • CAS. No.NA
  • Mol. F.C10H12N2O3
  • Mol. W.208.21 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 3
Domperidone Impurity 3
  • CAT. No.D090013
  • CAS. No.72798-66-4
  • Mol. F.C10H10N2O
  • Mol. W.174.20 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 4
Domperidone Impurity 4
  • CAT. No.D090014
  • CAS. No.39677-10-6
  • Mol. F.C17H16N4O2
  • Mol. W.308.33 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 8
Domperidone Impurity 8
  • CAT. No.D090015
  • CAS. No.142799-22-2
  • Mol. F.C13H16Cl2N2O
  • Mol. W.287.18 g/mol
  • Stock Status:Custom Synthesis
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1-Chloroprop-1-ene
1-Chloroprop-1-ene
  • CAT. No.D090016
  • CAS. No.590-21-6
  • Mol. F.C3H5Cl
  • Mol. W.76.52 g/mol
  • Stock Status:Custom Synthesis
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2-Chloroprop-1-ene
2-Chloroprop-1-ene
  • CAT. No.D090017
  • CAS. No.557-98-2
  • Mol. F.C3H5Cl
  • Mol. W.76.52 g/mol
  • Stock Status:Custom Synthesis
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1-3-chloropropyl-3-3-2-3-dihydro-2-oxo-1h-benzimidazol-1-yl-propyl-1-3-dihydro-2h-benzimidazol-2-one
1-3-chloropropyl-3-3-2-3-dihydro-2-oxo-1h-benzimidazol-1-yl-propyl-1-3-dihydro-2h-benzimidazol-2-one
  • CAT. No.D090018
  • CAS. No.NA
  • Mol. F.C20H21ClN4O2
  • Mol. W.384.86 g/mol
  • Stock Status:Custom Synthesis
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1-(3-bromopropyl)-3-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
1-(3-bromopropyl)-3-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
  • CAT. No.D090019
  • CAS. No.NA
  • Mol. F.C13H16BrClN2O
  • Mol. W.331.64 g/mol
  • Stock Status:Instock
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1,3-di-(3-bromopropyl)-1,3-dihydro-2H-benzimidazol-2-one
1,3-di-(3-bromopropyl)-1,3-dihydro-2H-benzimidazol-2-one
  • CAT. No.D090020
  • CAS. No.NA
  • Mol. F.C13H16Br2N2O
  • Mol. W.376.09 g/mol
  • Stock Status:Custom Synthesis
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3-(3-Hydroxypropyl)-1H-benzimidazol-2-one hydrate
3-(3-Hydroxypropyl)-1H-benzimidazol-2-one hydrate
  • CAT. No.D090021
  • CAS. No.NA
  • Mol. F.C10H14N2O3
  • Mol. W.210.23 g/mol
  • Stock Status:Custom Synthesis
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3-Prop-2-enyl-1H-benzimidazol-2-one
3-Prop-2-enyl-1H-benzimidazol-2-one
  • CAT. No.D090022
  • CAS. No.NA
  • Mol. F.C10H10N2O
  • Mol. W.174.20 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 6
Domperidone Impurity 6
  • CAT. No.D090023
  • CAS. No.NA
  • Mol. F.C23H24ClN5O3
  • Mol. W.453.92 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 5
Domperidone Impurity 5
  • CAT. No.D090024
  • CAS. No.87120-77-2
  • Mol. F.C14H21N3O2
  • Mol. W.263.34 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 7
Domperidone Impurity 7
  • CAT. No.D090025
  • CAS. No.103784-04-9
  • Mol. F.C10H11BrN2O
  • Mol. W.255.11 g/mol
  • Stock Status:Custom Synthesis
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Ethyl4-(2-nitrophenylamino)piperidine-1-Carboxylate
Ethyl4-(2-nitrophenylamino)piperidine-1-Carboxylate
  • CAT. No.D090026
  • CAS. No.85443-52-3
  • Mol. F.C14H19N3O4
  • Mol. W.293.32 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 2
Domperidone Impurity 2
  • CAT. No.D090027
  • CAS. No.53786-44-0
  • Mol. F.C14H18ClN3O4
  • Mol. W.327.76 g/mol
  • Stock Status:Custom Synthesis
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5-chloro-1-(1-nitrosopiperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
5-chloro-1-(1-nitrosopiperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
  • CAT. No.D090028
  • CAS. No.NA
  • Mol. F.C12H13ClN4O2
  • Mol. W.280.71 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Fumarate
Domperidone Fumarate
  • CAT. No.D090029
  • CAS. No.NA
  • Mol. F.C26H28ClN5O6
  • Mol. W.541.98 g/mol
  • Stock Status:Custom Synthesis
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Domperidone EP Impurity C
Domperidone EP Impurity C
  • CAT. No.D090030
  • CAS. No.NA
  • Mol. F.C22H24ClN5O3
  • Mol. W.441.91 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Domperidone
N-Nitroso Domperidone
  • CAT. No.D090031
  • CAS. No.NA
  • Mol. F.C22H23ClN6O3
  • Mol. W.454.91 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Domperidone Impurity 4
N-Nitroso Domperidone Impurity 4
  • CAT. No.D090032
  • CAS. No.NA
  • Mol. F.C22H22ClN7O4
  • Mol. W.483.90 g/mol
  • Stock Status:Custom Synthesis
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1-(3-(4-(6-chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidin-1-yl)propyl)-3-nitroso-1H-benzo[d]imidazol-2(3H)-one
1-(3-(4-(6-chloro-1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)piperidin-1-yl)propyl)-3-nitroso-1H-benzo[d]imidazol-2(3H)-one
  • CAT. No.D090033
  • CAS. No.NA
  • Mol. F.C22H23ClN6O3
  • Mol. W.454.91 g/mol
  • Stock Status:Custom Synthesis
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N-Isopropenyl-2-benzimidazolone
N-Isopropenyl-2-benzimidazolone
  • CAT. No.D090034
  • CAS. No.52099-72-6
  • Mol. F.C10H10N2O
  • Mol. W.174.20 g/mol
  • Stock Status:Instock
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Ethyl 4-(N-(2-aminophenyl)-N-nitrosoamino) piperidine-1-carboxylate
Ethyl 4-(N-(2-aminophenyl)-N-nitrosoamino) piperidine-1-carboxylate
  • CAT. No.D090035
  • CAS. No.NA
  • Mol. F.C14H20N4O3
  • Mol. W.292.33 g/mol
  • Stock Status:Custom Synthesis
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Hydroxy domperidone I
Hydroxy domperidone I
  • CAT. No.D090036
  • CAS. No.NA
  • Mol. F.C22H24ClN5O3
  • Mol. W.441.91 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 10
Domperidone Impurity 10
  • CAT. No.D090037
  • CAS. No.75655-44-6
  • Mol. F.C10H10N2O3
  • Mol. W.206.20 g/mol
  • Stock Status:Custom Synthesis
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5-Chloro-2-benzimidazolone
5-Chloro-2-benzimidazolone
  • CAT. No.D090038
  • CAS. No.2034-23-3
  • Mol. F.C7H5ClN2O
  • Mol. W.168.58 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Domperidone Impurity 6
N-Nitroso Domperidone Impurity 6
  • CAT. No.D090039
  • CAS. No.NA
  • Mol. F.C10H10ClN3O2
  • Mol. W.239.66 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 12
Domperidone Impurity 12
  • CAT. No.D090040
  • CAS. No.NA
  • Mol. F.C24H28ClN5O2S
  • Mol. W.486.03 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 9
Domperidone Impurity 9
  • CAT. No.D090041
  • CAS. No.NA
  • Mol. F.C10H14N2O3
  • Mol. W.210.23 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 11
Domperidone Impurity 11
  • CAT. No.D090042
  • CAS. No.NA
  • Mol. F.C13H14N2O
  • Mol. W.214.30 g/mol
  • Stock Status:Custom Synthesis
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Domperidone Impurity 13
Domperidone Impurity 13
  • CAT. No.D090043
  • CAS. No.62780-92-1
  • Mol. F.C10H12N2O2
  • Mol. W.192.22 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Domperidone-D6
Domperidone-D6
  • CAT. No.D090007
  • CAS. No.1329614-18-7
  • Mol. F.C22H18D6ClN5O2
  • Mol. W.431.95 g/mol
  • Stock Status:Custom Synthesis
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