Dofetilide Related Compounds & Impurities

Dofetilide is a Class III antiarrhythmic that selectively blocks the rapid component of the delayed rectifier potassium current (IKr), used for atrial fibrillation and flutter.

Simson Pharma Limited along with its subsidiary offices Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) is a trusted manufacturer and supplier of high-quality pharmaceutical reference standards, offering a comprehensive portfolio of Dofetilide reference standards, pharmacopeial and non-pharmacopeial Dofetilide impurities, related compounds, related substances, metabolites, stable isotope-labelled compounds, deuterium labelled compounds and nitrosamine (N-NO) reference standards.

These materials support pharmaceutical research and development, product development, ANDA and DMF submissions, quality control (QC), analytical method development and validation, stability studies, impurity identification, and genotoxic impurity assessment.

Our Dofetilide-related reference standards are thoroughly characterized using advanced analytical techniques and are supplied with comprehensive Certificates of Analysis (COA) and supporting analytical data from our USFDA certified, ISO 17025 and ISO 17034 accredited Lab, to meet global regulatory expectations. EP and USP traceable reference standards can also be provided upon request, subject to availability. Simson is also a provider of EP and USP traceable standards. To ensure consistent quality and reliability, our reference standards are periodically re-tested according to established quality management procedures.

Pharmaceutical Reference Standards / Impurity Standards

Dofetilide
Dofetilide
  • CAT. No.D760000
  • CAS. No.115256-11-6
  • Mol. F.C19H27N3O5S2
  • Mol. W.441.56 g/mol
  • Stock Status:Instock
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N-Desmethyl Dofetilide Hydrochloride Hydrate
N-Desmethyl Dofetilide Hydrochloride Hydrate
  • CAT. No.D760001
  • CAS. No.176447-94-2 (Free base)
  • Mol. F.C18H25N3O5S2.H2O.HCl
  • Mol. W.482.01 g/mol
  • Stock Status:Instock
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N-Desmethyl Dofetilide
N-Desmethyl Dofetilide
  • CAT. No.D760001A
  • CAS. No.176447-94-2
  • Mol. F.C18H25N3O5S2
  • Mol. W.427.54 g/mol
  • Stock Status:Instock
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N-(4-(2-Chloroethoxy)phenyl)methanesulfonamide
N-(4-(2-Chloroethoxy)phenyl)methanesulfonamide
  • CAT. No.D760003
  • CAS. No.115256-17-2
  • Mol. F.C9H12ClNO3S
  • Mol. W.249.72 g/mol
  • Stock Status:Instock
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Dofetilide Impurity 18
Dofetilide Impurity 18
  • CAT. No.D760004
  • CAS. No.115256-12-7
  • Mol. F.C18H25N3O3S
  • Mol. W.363.48 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethylsulfonyl-N`-Methylsulfonyl Dofetilide
N-Desmethylsulfonyl-N`-Methylsulfonyl Dofetilide
  • CAT. No.D760005
  • CAS. No.937194-99-5
  • Mol. F.C19H27N3O5S2
  • Mol. W.441.57 g/mol
  • Stock Status:Custom Synthesis
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N`-Desmethylsulfonyl-N-Methylsulfonyl Dofetilide
N`-Desmethylsulfonyl-N-Methylsulfonyl Dofetilide
  • CAT. No.D760006
  • CAS. No.937195-06-7
  • Mol. F.C19H27N3O5S2
  • Mol. W.441.57 g/mol
  • Stock Status:Custom Synthesis
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N`-Methylsulfonyl Dofetilide
N`-Methylsulfonyl Dofetilide
  • CAT. No.D760007
  • CAS. No.312315-47-2
  • Mol. F.C20H29N3O7S3
  • Mol. W.519.66 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 5
Dofetilide Impurity 5
  • CAT. No.D760008
  • CAS. No.NA
  • Mol. F.C16H20N2O6S2
  • Mol. W.400.47 g/mol
  • Stock Status:Instock
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Dofetilide EP Impurity H
Dofetilide EP Impurity H
  • CAT. No.D760009
  • CAS. No.NA
  • Mol. F.C21H31N3O7S3
  • Mol. W.533.68 g/mol
  • Stock Status:Custom Synthesis
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N-Desaminomethylsulfonyl-N-nitryl Dofetilide
N-Desaminomethylsulfonyl-N-nitryl Dofetilide
  • CAT. No.D760010
  • CAS. No.115256-45-6
  • Mol. F.C18H23N3O5S
  • Mol. W.393.46 g/mol
  • Stock Status:Custom Synthesis
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N'-Desaminomethylsulfonyl-N'-nitryl Dofetilide
N'-Desaminomethylsulfonyl-N'-nitryl Dofetilide
  • CAT. No.D760011
  • CAS. No.115256-44-5
  • Mol. F.C18H23N3O5S
  • Mol. W.393.46 g/mol
  • Stock Status:Custom Synthesis
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Dichlorphenamide
Dichlorphenamide
  • CAT. No.D760012
  • CAS. No.NA
  • Mol. F.C6H6Cl2N2O4S2
  • Mol. W.305.16 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide N-Oxide
Dofetilide N-Oxide
  • CAT. No.D760013
  • CAS. No.144449-71-8
  • Mol. F.C19H27N3O6S2
  • Mol. W.457.56 g/mol
  • Stock Status:Instock
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N,N`-Dimethylsulfonyl Dofetilide
N,N`-Dimethylsulfonyl Dofetilide
  • CAT. No.D760015
  • CAS. No.937194-91-7
  • Mol. F.C21H31N3O9S4
  • Mol. W.597.77 g/mol
  • Stock Status:Instock
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Dofetilide Impurity 2
Dofetilide Impurity 2
  • CAT. No.D760016
  • CAS. No.14467-69-7
  • Mol. F.C14H12N2O6
  • Mol. W.304.26 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 13
Dofetilide Impurity 13
  • CAT. No.D760017
  • CAS. No.115256-15-0
  • Mol. F.C10H16N2O3S
  • Mol. W.244.31 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 14
Dofetilide Impurity 14
  • CAT. No.D760018
  • CAS. No.115256-16-1
  • Mol. F.C10H16N2O2S
  • Mol. W.228.31 g/mol
  • Stock Status:Custom Synthesis
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Methyl-(4-Nitrophenylethyl)-(4-Nitrophenoxyethyl)Amine
Methyl-(4-Nitrophenylethyl)-(4-Nitrophenoxyethyl)Amine
  • CAT. No.D760019
  • CAS. No.115287-37-1
  • Mol. F.C17H19N3O5
  • Mol. W.345.35 g/mol
  • Stock Status:Instock
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Dofetilide Impurity 7
Dofetilide Impurity 7
  • CAT. No.D760020
  • CAS. No.115256-13-8
  • Mol. F.C17H23N3O
  • Mol. W.285.38 g/mol
  • Stock Status:Custom Synthesis
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N-(4-(2-Chloroethoxy)phenyl)methanesulfonamide
N-(4-(2-Chloroethoxy)phenyl)methanesulfonamide
  • CAT. No.D760021
  • CAS. No.115256-17-2
  • Mol. F.C9H12ClNO3S
  • Mol. W.249.72 g/mol
  • Stock Status:Custom Synthesis
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1-(2-Bromoethoxy)-2-Nitrobenzene
1-(2-Bromoethoxy)-2-Nitrobenzene
  • CAT. No.D760022
  • CAS. No.18800-37-8
  • Mol. F.C8H8BrNO3
  • Mol. W.246.06 g/mol
  • Stock Status:Custom Synthesis
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1-Nitro-4-[2-(4-Nitrophenoxy)Ethoxy]Benzene
1-Nitro-4-[2-(4-Nitrophenoxy)Ethoxy]Benzene
  • CAT. No.D760023
  • CAS. No.14467-69-7
  • Mol. F.C14H12N2O6
  • Mol. W.304.25 g/mol
  • Stock Status:Custom Synthesis
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N-Methyl-2-(4-Nitrophenyl)Acetamide
N-Methyl-2-(4-Nitrophenyl)Acetamide
  • CAT. No.D760024
  • CAS. No.98245-61-5
  • Mol. F.C9H10N2O3
  • Mol. W.194.19 g/mol
  • Stock Status:Custom Synthesis
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4-Nitrophenylacetic Acid
4-Nitrophenylacetic Acid
  • CAT. No.D760025
  • CAS. No.104-03-0
  • Mol. F.C8H7NO4
  • Mol. W.181.15 g/mol
  • Stock Status:Custom Synthesis
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Methyl 2-(4-nitrophenyl)acetate
Methyl 2-(4-nitrophenyl)acetate
  • CAT. No.D760026
  • CAS. No.2945-08-6
  • Mol. F.C9H9NO4
  • Mol. W.195.17 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethylsulfonyl-N`-methylsulfonyl Dofetilide
N-Desmethylsulfonyl-N`-methylsulfonyl Dofetilide
  • CAT. No.D760027
  • CAS. No.937194-99-5
  • Mol. F.C19H27N3O5S2
  • Mol. W.441.56 g/mol
  • Stock Status:Custom Synthesis
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N`-Desmethylsulfonyl-N-Methylsulfonyl Dofetilide
N`-Desmethylsulfonyl-N-Methylsulfonyl Dofetilide
  • CAT. No.D760028
  • CAS. No.937195-06-7
  • Mol. F.C19H27N3O5S2
  • Mol. W.441.56 g/mol
  • Stock Status:Custom Synthesis
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N-methyl-2-(2-Nitrophenyl)Acetamide
N-methyl-2-(2-Nitrophenyl)Acetamide
  • CAT. No.D760029
  • CAS. No.4103-44-0
  • Mol. F.C9H10N2O3
  • Mol. W.194.19 g/mol
  • Stock Status:Custom Synthesis
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2-(4-(Methylsulfonamido)Phenoxy)Acetic Acid
2-(4-(Methylsulfonamido)Phenoxy)Acetic Acid
  • CAT. No.D760030
  • CAS. No.103790-20-1
  • Mol. F.C9H11NO5S
  • Mol. W.245.25 g/mol
  • Stock Status:Custom Synthesis
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2-(4-(Methylsulfonamido)Phenyl)Acetic Acid
2-(4-(Methylsulfonamido)Phenyl)Acetic Acid
  • CAT. No.D760031
  • CAS. No.56205-88-0
  • Mol. F.C9H11NO4S
  • Mol. W.229.25 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 20
Dofetilide Impurity 20
  • CAT. No.D760032
  • CAS. No.NA
  • Mol. F.C15H15N3O5
  • Mol. W.317.30 g/mol
  • Stock Status:Instock
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Dofetilide Impurity 19
Dofetilide Impurity 19
  • CAT. No.D760033
  • CAS. No.NA
  • Mol. F.C15H15N3O5
  • Mol. W.317.30 g/mol
  • Stock Status:Instock
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methyl[2-(3-nitrophenyl)ethyl]amine Hydrochloride
methyl[2-(3-nitrophenyl)ethyl]amine Hydrochloride
  • CAT. No.D760034
  • CAS. No.1803604-79-6
  • Mol. F.C9H13ClN2O2
  • Mol. W.216.66 g/mol
  • Stock Status:Custom Synthesis
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N-methyl-2-(2-nitrophenyl)ethan-1-amine hydrochloride
N-methyl-2-(2-nitrophenyl)ethan-1-amine hydrochloride
  • CAT. No.D760035
  • CAS. No.NA
  • Mol. F.C9H12N2O2.HCl
  • Mol. W.216.66 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 3
Dofetilide Impurity 3
  • CAT. No.D760036
  • CAS. No.85176-37-0
  • Mol. F.C9H12N2O2
  • Mol. W.180.20 g/mol
  • Stock Status:Custom Synthesis
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N-Methylsulfonyl Dofetilide
N-Methylsulfonyl Dofetilide
  • CAT. No.D760037
  • CAS. No.937195-03-4
  • Mol. F.C20H29N3O7S3
  • Mol. W.519.66 g/mol
  • Stock Status:Custom Synthesis
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(N-(4-(2-(Methylamino) ethoxy) phenyl) methanesulfonamide Hydrobromide)
(N-(4-(2-(Methylamino) ethoxy) phenyl) methanesulfonamide Hydrobromide)
  • CAT. No.D760038
  • CAS. No.NA
  • Mol. F.C10H17BrN2O3S
  • Mol. W.325.22 g/mol
  • Stock Status:Custom Synthesis
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N-(4-(2-(Methyl(nitroso)amino)ethoxy)phenyl)methanesulfonamide
N-(4-(2-(Methyl(nitroso)amino)ethoxy)phenyl)methanesulfonamide
  • CAT. No.D760039
  • CAS. No.NA
  • Mol. F.C10H15N3O4S
  • Mol. W.273.31 g/mol
  • Stock Status:Instock
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N-Nitroso Dofetilide Impurity 1
N-Nitroso Dofetilide Impurity 1
  • CAT. No.D760040
  • CAS. No.NA
  • Mol. F.C18H24N4O6S2
  • Mol. W.456.54 g/mol
  • Stock Status:Instock
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Dofetilide Impurity 16
Dofetilide Impurity 16
  • CAT. No.D760041
  • CAS. No.1226154-86-4
  • Mol. F.C10H16N2O
  • Mol. W.180.30 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Impurity 17
Dofetilide Impurity 17
  • CAT. No.D760042
  • CAS. No.115256-14-9
  • Mol. F.C18H25N3O3S
  • Mol. W.363.48 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Dofetilide Impurity 3
N-Nitroso Dofetilide Impurity 3
  • CAT. No.D760043
  • CAS. No.NA
  • Mol. F.C10H15N3O3S
  • Mol. W.257.31 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 7
Dofetilide Nitroso Impurity 7
  • CAT. No.D760044
  • CAS. No.NA
  • Mol. F.C9H13N3O2
  • Mol. W.195.22 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 10
Dofetilide Nitroso Impurity 10
  • CAT. No.D760045
  • CAS. No.NA
  • Mol. F.C9H11N3O4
  • Mol. W.225.20 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 4
Dofetilide Nitroso Impurity 4
  • CAT. No.D760046
  • CAS. No.NA
  • Mol. F.C17H22N4O4S
  • Mol. W.378.45 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 10
Dofetilide Nitroso Impurity 10
  • CAT. No.D760047
  • CAS. No.NA
  • Mol. F.C16H16N4O6
  • Mol. W.360.32 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 6
Dofetilide Nitroso Impurity 6
  • CAT. No.D760048
  • CAS. No.NA
  • Mol. F.C16H20N4O2
  • Mol. W.300.36 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 9
Dofetilide Nitroso Impurity 9
  • CAT. No.D760049
  • CAS. No.NA
  • Mol. F.C9H11N3O3
  • Mol. W.209.20 g/mol
  • Stock Status:Custom Synthesis
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Dofetilide Nitroso Impurity 5
Dofetilide Nitroso Impurity 5
  • CAT. No.D760050
  • CAS. No.NA
  • Mol. F.C9H13N3O
  • Mol. W.179.22 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Dofetilide D4
Dofetilide D4
  • CAT. No.D760002
  • CAS. No.1189700-56-8
  • Mol. F.C19H23D4N3O5S2
  • Mol. W.445.59 g/mol
  • Stock Status:Instock
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