Diltiazem

Diltiazem is a benzothiazepine calcium channel blocker that slows AV-nodal conduction and dilates coronary and peripheral vasculature, used for angina, hypertension and rate control in supraventricular arrhythmias. Simson Pharma's Diltiazem reference standard and impurities support the high-volume compendial testing this widely prescribed cardiovascular drug demands.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Diltiazem Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Diltiazem Hydrochloride
Diltiazem Hydrochloride
  • CAT. No.D450000
  • CAS. No.33286-22-5
  • Mol. F.C22H27ClN2O4S
  • Mol. W.450.98 g/mol
  • Stock Status:Instock
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Diltiazem
Diltiazem
  • CAT. No.D450000A
  • CAS. No.42399-41-7
  • Mol. F.C22H26N2O4S
  • Mol. W.414.52 g/mol
  • Stock Status:Instock
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Diltiazem Hydrochloride
Diltiazem Hydrochloride
  • CAT. No.D450000B
  • CAS. No.33286-22-5
  • Mol. F.C22H26N2O4S.HCl
  • Mol. W.450.98 g/mol
  • Stock Status:Under Synthesis
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Diltiazem Impurity E
Diltiazem Impurity E
  • CAT. No.D450001
  • CAS. No.42399-49-5
  • Mol. F.C16H15NO3S
  • Mol. W.301.36g/mol
  • Stock Status:Instock
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Diltiazem EP Impurity F
Diltiazem EP Impurity F
  • CAT. No.D450002
  • CAS. No.42399-40-6
  • Mol. F.C20H24N2O3S
  • Mol. W.372.50 g/mol
  • Stock Status:Under Synthesis
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Desacetyl Diltiazem Hydrochloride
Desacetyl Diltiazem Hydrochloride
  • CAT. No.D450002A
  • CAS. No.75472-91-2
  • Mol. F.C20H25ClN2O3S
  • Mol. W.408.94 g/mol
  • Stock Status:Instock
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Desacetyl Diltiazem Hydrochloride (Mixture)
Desacetyl Diltiazem Hydrochloride (Mixture)
  • CAT. No.D450002C
  • CAS. No.23515-45-9
  • Mol. F.C20H24N2O3S.HCl
  • Mol. W.408.94 g/mol
  • Stock Status:Instock
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Desacetyl O- dimethyl diltiazem
Desacetyl O- dimethyl diltiazem
  • CAT. No.D450004
  • CAS. No.NA
  • Mol. F.C18H17NO4S
  • Mol. W.343.40 g/mol
  • Stock Status:Custom Synthesis
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N-desmethyl Diltiazem Hydrochloride EP impurity D
N-desmethyl Diltiazem Hydrochloride EP impurity D
  • CAT. No.D450005
  • CAS. No.130606-60-9
  • Mol. F.C21H24N2O4S.HCl
  • Mol. W.436.95 g/mol
  • Stock Status:Instock
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Diltiazem EP Impurity A
Diltiazem EP Impurity A
  • CAT. No.D450006
  • CAS. No.111188-71-7
  • Mol. F.C22H26N2O4S
  • Mol. W.414.52 g/mol
  • Stock Status:Under Synthesis
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Diltiazem Imp C
Diltiazem Imp C
  • CAT. No.D450007
  • CAS. No.142926-07-6
  • Mol. F.C21H25ClN2O4S
  • Mol. W.436.95 g/mol
  • Stock Status:Limited Stock
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Diltiazem Related Compund C
Diltiazem Related Compund C
  • CAT. No.D450007A
  • CAS. No.142926-07-6
  • Mol. F.C21H24N2O4S
  • Mol. W.400.49 g/mol
  • Stock Status:Instock
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N-Desmethyl O-Desacetyl Diltiazem
N-Desmethyl O-Desacetyl Diltiazem
  • CAT. No.D450008
  • CAS. No.81353-09-5
  • Mol. F.C19H22N2O3S
  • Mol. W.358.45 g/mol
  • Stock Status:Instock
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N-Desmethyl O-Desacetyl Diltiazem Hydrochloride
N-Desmethyl O-Desacetyl Diltiazem Hydrochloride
  • CAT. No.D450008A
  • CAS. No.84903-78-6
  • Mol. F.C19H22N2O3S. HCl
  • Mol. W.394.92 g/mol
  • Stock Status:Instock
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N,N-Didesmethyl Diltiazem Hydrochloride
N,N-Didesmethyl Diltiazem Hydrochloride
  • CAT. No.D450009
  • CAS. No.116050-35-2
  • Mol. F.C20H22N2O4S.HCl
  • Mol. W.422.93 g/mol
  • Stock Status:Custom Synthesis
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N,N-Didesmethyl Diltiazem
N,N-Didesmethyl Diltiazem
  • CAT. No.D450009A
  • CAS. No.NA
  • Mol. F.C20H22N2O4S
  • Mol. W.386.46 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem EP Impurity B
Diltiazem EP Impurity B
  • CAT. No.D450010
  • CAS. No.87447-47-0
  • Mol. F.C18H17NO4S
  • Mol. W.343.40 g/mol
  • Stock Status:Instock
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Diltiazem EP Impurity H
Diltiazem EP Impurity H
  • CAT. No.D450015
  • CAS. No.115992-91-1
  • Mol. F.C17H18N2O3S
  • Mol. W.330.40 g/mol
  • Stock Status:Instock
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Diltiazem Related Compound H
Diltiazem Related Compound H
  • CAT. No.D450015B
  • CAS. No.115992-91-1
  • Mol. F.C17H18N2O3S
  • Mol. W.330.40 g/mol
  • Stock Status:Limited Stock
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Desacetyl Diltiazem
Desacetyl Diltiazem
  • CAT. No.D450016
  • CAS. No.42399-40-6
  • Mol. F.C20H24N2O3S
  • Mol. W.372.50 g/mol
  • Stock Status:Custom Synthesis
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L-Diltiazem
L-Diltiazem
  • CAT. No.D450018
  • CAS. No.1217650-51-5
  • Mol. F.C22H26N2O4S
  • Mol. W.414.52 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem EP Impurity A Hydrochloride
Diltiazem EP Impurity A Hydrochloride
  • CAT. No.D450019
  • CAS. No.103532-27-0
  • Mol. F.C22H27ClN2O4S
  • Mol. W.450.98 g/mol
  • Stock Status:Under Synthesis
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Diltiazem Sulfoxide
Diltiazem Sulfoxide
  • CAT. No.D450021
  • CAS. No.370094-12-5
  • Mol. F.C22H26N2O5S
  • Mol. W.430.52 g/mol
  • Stock Status:Instock
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Diltiazem N-Oxide
Diltiazem N-Oxide
  • CAT. No.D450022
  • CAS. No.142843-04-7
  • Mol. F.C22H26N2O5S
  • Mol. W.430.52 g/mol
  • Stock Status:Instock
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Diltiazem N-Oxide O-Desacetyl Impurity
Diltiazem N-Oxide O-Desacetyl Impurity
  • CAT. No.D450023
  • CAS. No.122619-90-3
  • Mol. F.CHNOS
  • Mol. W.388.48 g/mol
  • Stock Status:Instock
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Desacetyl N,O-didesmethyl Diltiazem
Desacetyl N,O-didesmethyl Diltiazem
  • CAT. No.D450024
  • CAS. No.86408-42-6
  • Mol. F.C18H20N2O3S
  • Mol. W.344.43 g/mol
  • Stock Status:Instock
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DTZ-II Diltiazem impurity
DTZ-II Diltiazem impurity
  • CAT. No.D450026
  • CAS. No.NA
  • Mol. F.C20H19NO4S
  • Mol. W.369.40 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem EP Impurity G Hydrochloride
Diltiazem EP Impurity G Hydrochloride
  • CAT. No.D450027
  • CAS. No.68767-04-4
  • Mol. F.C19H22N2O3S.HCl
  • Mol. W.394.92 g/mol
  • Stock Status:Instock
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Diltiazem Sulphone
Diltiazem Sulphone
  • CAT. No.D450029
  • CAS. No.NA
  • Mol. F.C22H26N2O6S
  • Mol. W.446.52 g/mol
  • Stock Status:Instock
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Diltiazem Sulphoxide N-Oxide
Diltiazem Sulphoxide N-Oxide
  • CAT. No.D450030
  • CAS. No.NA
  • Mol. F.C22H26N2O6S
  • Mol. W.446.52 g/mol
  • Stock Status:Instock
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Diltiazem Sulphone N-oxide
Diltiazem Sulphone N-oxide
  • CAT. No.D450031
  • CAS. No.NA
  • Mol. F.C22H26N2O7S
  • Mol. W.462.52 g/mol
  • Stock Status:Instock
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Diltiazem Monohydrolysed Impurity
Diltiazem Monohydrolysed Impurity
  • CAT. No.D450032
  • CAS. No.NA
  • Mol. F.C22H28N2O5S
  • Mol. W.432.53 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Dihydrolysed Impurity
Diltiazem Dihydrolysed Impurity
  • CAT. No.D450033
  • CAS. No.NA
  • Mol. F.C20H26N2O4S
  • Mol. W.390.50 g/mol
  • Stock Status:Custom Synthesis
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(2S,3S)-2-(4-methoxyphenyl)-4-oxo-5-vinyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
(2S,3S)-2-(4-methoxyphenyl)-4-oxo-5-vinyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
  • CAT. No.D450034
  • CAS. No.NA
  • Mol. F.C20H19NO4S
  • Mol. W.369.43 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem DTZ-I Impurity
Diltiazem DTZ-I Impurity
  • CAT. No.D450035
  • CAS. No.30842-48-9
  • Mol. F.C19H19NO4S
  • Mol. W.357.42 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 9
Diltiazem Impurity 9
  • CAT. No.D450038
  • CAS. No.NA
  • Mol. F.C17H17NO3S
  • Mol. W.315.39 g/mol
  • Stock Status:Custom Synthesis
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N-Acetyl Diltiazem
N-Acetyl Diltiazem
  • CAT. No.D450039
  • CAS. No.NA
  • Mol. F.C23H26N2O5S
  • Mol. W.442.53 g/mol
  • Stock Status:Instock
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(2R-trans)-Diltiazem Hydrochloride
(2R-trans)-Diltiazem Hydrochloride
  • CAT. No.D450040
  • CAS. No.NA
  • Mol. F.C22H27N2O4SCl
  • Mol. W.450.98 g/mol
  • Stock Status:Custom Synthesis
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N-desmethyl N-nitroso Diltiazem
N-desmethyl N-nitroso Diltiazem
  • CAT. No.D450043
  • CAS. No.NA
  • Mol. F.C21H23N3O5S
  • Mol. W.429.49 g/mol
  • Stock Status:Instock
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N-Nitroso Diltiazem EP Impurity G
N-Nitroso Diltiazem EP Impurity G
  • CAT. No.D450044
  • CAS. No.NA
  • Mol. F.C19H21N3O4S
  • Mol. W.387.45 g/mol
  • Stock Status:Custom Synthesis
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N-nitroso-Chloroethyl methylamine hydrochloride
N-nitroso-Chloroethyl methylamine hydrochloride
  • CAT. No.D450045
  • CAS. No.NA
  • Mol. F.C3H8Cl2N2O
  • Mol. W.159.01 g/mol
  • Stock Status:Custom Synthesis
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(2S,3S)-3-acetyloxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4(5H)-one.
(2S,3S)-3-acetyloxy-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4(5H)-one.
  • CAT. No.D450046
  • CAS. No.NA
  • Mol. F.C21H24N2O4S
  • Mol. W.400.49 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 4
Diltiazem Impurity 4
  • CAT. No.D450047
  • CAS. No.42399-51-9
  • Mol. F.C16H15NO3S
  • Mol. W.301.36 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem-2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity
Diltiazem-2-Epimer O-Desacetyl N-Desdimethylaminoethyl Impurity
  • CAT. No.D450048
  • CAS. No.132830-17-2
  • Mol. F.C16H15NO3S
  • Mol. W.301.36 g/mol
  • Stock Status:Custom Synthesis
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L-cis-Diltiazem Hydrochloride
L-cis-Diltiazem Hydrochloride
  • CAT. No.D450049
  • CAS. No.42399-54-2
  • Mol. F.C22H27ClN2O4S
  • Mol. W.450.98 g/mol
  • Stock Status:Custom Synthesis
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Deacetyl-O-demethyl diltiazem
Deacetyl-O-demethyl diltiazem
  • CAT. No.D450050
  • CAS. No.84903-82-2
  • Mol. F.C19H22N2O3S
  • Mol. W.358.45 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Formamide Impurity
Diltiazem Formamide Impurity
  • CAT. No.D450051
  • CAS. No.NA
  • Mol. F.C22H24N2O5S
  • Mol. W.428.50 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 8
Diltiazem Impurity 8
  • CAT. No.D450055
  • CAS. No.42399-48-4
  • Mol. F.C16H17NO4S
  • Mol. W.319.38 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Desmethyl Diltiazem
N-Nitroso Desmethyl Diltiazem
  • CAT. No.D450056
  • CAS. No.3036581-85-5
  • Mol. F.C21H23N3O5S
  • Mol. W.429.49 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 10
Diltiazem Impurity 10
  • CAT. No.D450058
  • CAS. No.NA
  • Mol. F.C11H12O4
  • Mol. W.208.21 g/mol
  • Stock Status:Custom Synthesis
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Deacetyl-N-monodemethyldiltiazem
Deacetyl-N-monodemethyldiltiazem
  • CAT. No.D450059
  • CAS. No.40861-80-1
  • Mol. F.C19H22N2O3S.HCl
  • Mol. W.394.92 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 2
Diltiazem Impurity 2
  • CAT. No.D450060
  • CAS. No.NA
  • Mol. F.C24H26NO5.C4H12N
  • Mol. W.421.81 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Impurity 3
Diltiazem Impurity 3
  • CAT. No.D450061
  • CAS. No.NA
  • Mol. F.C11H11O4.Na
  • Mol. W.230.19 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Diltiazem-D3 Hydrochloride
Diltiazem-D3 Hydrochloride
  • CAT. No.D450003
  • CAS. No.1217860-13-3
  • Mol. F.C22H24D3ClN2O4S
  • Mol. W.454.00 g/mol
  • Stock Status:Under Synthesis
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Diltiazem-D4 Hydrochloride
Diltiazem-D4 Hydrochloride
  • CAT. No.D450011
  • CAS. No.1217769-52-2
  • Mol. F.C22H22D4N2O4S.HCl
  • Mol. W.455.00 g/mol
  • Stock Status:Instock
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Desacetyl Diltiazem D4 Hydrochloride
Desacetyl Diltiazem D4 Hydrochloride
  • CAT. No.D450013
  • CAS. No.NA
  • Mol. F.C20H21D4ClN2O3S
  • Mol. W.412.97 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethyl Diltiazem D4 Hydrochloride
N-Desmethyl Diltiazem D4 Hydrochloride
  • CAT. No.D450017
  • CAS. No.Freebase115992-91-1
  • Mol. F.C21H20D4N2O4S.HCl
  • Mol. W.440.98 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem D6
Diltiazem D6
  • CAT. No.D450020
  • CAS. No.1242184-41-3
  • Mol. F.C22H20D6N2O4S
  • Mol. W.420.55 g/mol
  • Stock Status:Custom Synthesis
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Desacetyl Diltiazem D4
Desacetyl Diltiazem D4
  • CAT. No.D450036
  • CAS. No.112259-40-2
  • Mol. F.C20H20D4N2O3S
  • Mol. W.376.51 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem Hydrochloride Salt -D2
Diltiazem Hydrochloride Salt -D2
  • CAT. No.D450041
  • CAS. No.NA
  • Mol. F.C22H23D4ClN2O4S
  • Mol. W.455.00 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem-D3 Hydrochloride
Diltiazem-D3 Hydrochloride
  • CAT. No.D450042
  • CAS. No.1217623-80-7
  • Mol. F.C22H24D3ClN2O4S
  • Mol. W.454.00 g/mol
  • Stock Status:Custom Synthesis
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N-Desmethyl Diltiazem-D3 Hydrochloride
N-Desmethyl Diltiazem-D3 Hydrochloride
  • CAT. No.D450052
  • CAS. No.NA
  • Mol. F.C22H21D5N2O4S.HCl
  • Mol. W.439.97 g/mol
  • Stock Status:Custom Synthesis
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Desacetyl Diltiazem D3
Desacetyl Diltiazem D3
  • CAT. No.D450053
  • CAS. No.1246815-32-6
  • Mol. F.C20H21D3N2O3S
  • Mol. W.375.50 g/mol
  • Stock Status:Custom Synthesis
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Diltiazem D6 Hydrochloride
Diltiazem D6 Hydrochloride
  • CAT. No.D450057
  • CAS. No.1309283-34-8
  • Mol. F.C22H20D6N2O4S.HCl
  • Mol. W.457.02
  • Stock Status:Instock
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