Darifenacin

Darifenacin is a selective muscarinic M3 receptor antagonist that reduces detrusor muscle contractility, used for the treatment of overactive bladder syndrome with reduced CNS side effects due to its M3 subtype selectivity. Simson Pharma's Darifenacin reference standard and impurities support stability-indicating testing for this urology-focused anticholinergic.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Darifenacin Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Darifenacin
Darifenacin
  • CAT. No.D070000
  • CAS. No.133099-04-4
  • Mol. F.C28H30N2O2
  • Mol. W.426.55 g/mol
  • Stock Status:Limited Stock
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Darifenacin Pyrrolidine Impurity (S)-Isomer
Darifenacin Pyrrolidine Impurity (S)-Isomer
  • CAT. No.D070001
  • CAS. No.134002-26-9
  • Mol. F.C18H20N2O.C4H6O6
  • Mol. W.430.46 g/mol
  • Stock Status:Instock
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Darifenacin Impurity B
Darifenacin Impurity B
  • CAT. No.D070002
  • CAS. No.127264-14-6
  • Mol. F.C10H11BrO
  • Mol. W.227.10 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity C
Darifenacin Impurity C
  • CAT. No.D070003
  • CAS. No.NA
  • Mol. F.C20H20N2O4
  • Mol. W.352.38 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity C Hydrobromide salt
Darifenacin Impurity C Hydrobromide salt
  • CAT. No.D070003A
  • CAS. No.194602-27-2
  • Mol. F.C18H19N2Br
  • Mol. W.343.26 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Racemic Mixture Hydrobromide Salt
Darifenacin Racemic Mixture Hydrobromide Salt
  • CAT. No.D070004
  • CAS. No.NA
  • Mol. F.C28H30N2O2.HBr
  • Mol. W.507.47 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin R Isomer
Darifenacin R Isomer
  • CAT. No.D070005
  • CAS. No.1092800-15-1
  • Mol. F.C28H30N2O2.HBr
  • Mol. W.507.46 g/mol
  • Stock Status:Limited Stock
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Darifenacin S Isomer
Darifenacin S Isomer
  • CAT. No.D070006
  • CAS. No.133099-07-7
  • Mol. F.C28H31BrN2O2
  • Mol. W.507.46 g/mol
  • Stock Status:Limited Stock
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Darifenacin N-Oxide
Darifenacin N-Oxide
  • CAT. No.D070008
  • CAS. No.1391080-40-2
  • Mol. F.C28H30N2O3
  • Mol. W.442.56 g/mol
  • Stock Status:Under Synthesis
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Darifenacin Impurity D
Darifenacin Impurity D
  • CAT. No.D070009
  • CAS. No.NA
  • Mol. F.C38H41N2O3
  • Mol. W.572.74 g/ mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity D
Darifenacin Impurity D
  • CAT. No.D070009A
  • CAS. No.1396968-57-2
  • Mol. F.C38H41BrN2O3
  • Mol. W.653.65 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin KSM-II B(1-tosyl-(3S)-hydrox
Darifenacin KSM-II B(1-tosyl-(3S)-hydrox
  • CAT. No.D070010
  • CAS. No.133034-00-1
  • Mol. F.C11H15NO3S
  • Mol. W.241.31 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin KSM-II C (1-tosyl-(3S)-tosyl)
Darifenacin KSM-II C (1-tosyl-(3S)-tosyl)
  • CAT. No.D070011
  • CAS. No.NA
  • Mol. F.C18H21NO5S2
  • Mol. W.395.49 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Oxidized Impurity
Darifenacin Oxidized Impurity
  • CAT. No.D070012
  • CAS. No.133033-99-5
  • Mol. F.C28H28N2O2
  • Mol. W.424.53 g/mol
  • Stock Status:Instock
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Darifenacin Oxidized Impurity Hydrobromide
Darifenacin Oxidized Impurity Hydrobromide
  • CAT. No.D070012A
  • CAS. No.NA
  • Mol. F.C28H28N2O2.HBr
  • Mol. W.505.45 g/mol
  • Stock Status:Custom Synthesis
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Diphenylacetonitrile
Diphenylacetonitrile
  • CAT. No.D070013
  • CAS. No.86-29-3
  • Mol. F.C14H11N
  • Mol. W.193.24 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Nitrile Impurity
Darifenacin Nitrile Impurity
  • CAT. No.D070014
  • CAS. No.252317-48-9
  • Mol. F.C28H28N2O
  • Mol. W.408.53 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity A
Darifenacin Impurity A
  • CAT. No.D070015
  • CAS. No.1048979-16-3
  • Mol. F.C28H29NO3
  • Mol. W.427.53 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin EP Impurity A Hydrobromide
Darifenacin EP Impurity A Hydrobromide
  • CAT. No.D070015A
  • CAS. No.NA
  • Mol. F.C28H29NO3.HBr
  • Mol. W.508.45 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity C
Darifenacin Impurity C
  • CAT. No.D070016
  • CAS. No.NA
  • Mol. F.C28H30N2O3
  • Mol. W.442.56 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin 3-Hydroxy Impurity
Darifenacin 3-Hydroxy Impurity
  • CAT. No.D070017
  • CAS. No.206048-82-0
  • Mol. F.C28H30N2O3
  • Mol. W.442.56 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin 5-Carboxymethyl Impurity
Darifenacin 5-Carboxymethyl Impurity
  • CAT. No.D070018
  • CAS. No.69999-16-2
  • Mol. F.C10H10O3
  • Mol. W.178.19 g/mol
  • Stock Status:Instock
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Darifenacin EP Impurity H
Darifenacin EP Impurity H
  • CAT. No.D070019
  • CAS. No.NA
  • Mol. F.C47H50N4O3
  • Mol. W.718.95 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Dimer-2 Impurity
Darifenacin Dimer-2 Impurity
  • CAT. No.D070020
  • CAS. No.2280857-32-9
  • Mol. F.C38H40N2O3
  • Mol. W.572.74 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Dimer-2 Impurity Hydrochloride salt
Darifenacin Dimer-2 Impurity Hydrochloride salt
  • CAT. No.D070020A
  • CAS. No.2280857-32-9(free acid)
  • Mol. F.C38H41ClN2O3
  • Mol. W.609.20 g/mol
  • Stock Status:Custom Synthesis
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7-Bromo Darifenacin
7-Bromo Darifenacin
  • CAT. No.D070021
  • CAS. No.1391080-43-5
  • Mol. F.C28H29BrN2O2
  • Mol. W.505.45 g/mol
  • Stock Status:Custom Synthesis
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2-(2,3-dihydrobenzofuran-7-yl)acetic acid
2-(2,3-dihydrobenzofuran-7-yl)acetic acid
  • CAT. No.D070022
  • CAS. No.152149-94-5
  • Mol. F.C10H10O3
  • Mol. W.178.18 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Pyrrolidine Impurity Racemate
Darifenacin Pyrrolidine Impurity Racemate
  • CAT. No.D070023
  • CAS. No.103887-32-7
  • Mol. F.C18H20N2O
  • Mol. W.280.36 g/mol
  • Stock Status:Custom Synthesis
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5-(2-Bromoethyl)benzofuran
5-(2-Bromoethyl)benzofuran
  • CAT. No.D070024
  • CAS. No.133034-06-7
  • Mol. F.C10H9BrO
  • Mol. W.225.08 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Vinylbenzofuran Impurity
Darifenacin Vinylbenzofuran Impurity
  • CAT. No.D070025
  • CAS. No.633335-98-5
  • Mol. F.C10H8O
  • Mol. W.144.10 g/mol
  • Stock Status:Custom Synthesis
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(S)-2,2-diphenyl-2-(pyrrolidin-3-yl)acetic acid
(S)-2,2-diphenyl-2-(pyrrolidin-3-yl)acetic acid
  • CAT. No.D070026
  • CAS. No.NA
  • Mol. F.C18H19NO2
  • Mol. W.281.34 g/mol
  • Stock Status:Custom Synthesis
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3-cyanodiphenyl-methyl-1-2-2-3-dihydrobenzofuran-5-yl-ethyl-pyrrolidine-hydrobromide
3-cyanodiphenyl-methyl-1-2-2-3-dihydrobenzofuran-5-yl-ethyl-pyrrolidine-hydrobromide
  • CAT. No.D070027
  • CAS. No.NA
  • Mol. F.C28H29BrN2O
  • Mol. W.489.45 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin 7-Bromoethyl Impurity
Darifenacin 7-Bromoethyl Impurity
  • CAT. No.D070028
  • CAS. No.1598271-92-1
  • Mol. F.C10H11BrO
  • Mol. W.227.10 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Carboxylic Acid Impurity
Darifenacin Carboxylic Acid Impurity
  • CAT. No.D070029
  • CAS. No.NA
  • Mol. F.C28H29NO3
  • Mol. W.427.53 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Bromo Impurity
Darifenacin Bromo Impurity
  • CAT. No.D070030
  • CAS. No.NA
  • Mol. F.C28H29BrN2O2
  • Mol. W.505.46 g/mol
  • Stock Status:Custom Synthesis
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2-(2,3-dihydro-1-benzofuran-5-yl)ethanol
2-(2,3-dihydro-1-benzofuran-5-yl)ethanol
  • CAT. No.D070032
  • CAS. No.87776-76-9
  • Mol. F.C10H12O2
  • Mol. W.164.20 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 5
Darifenacin Impurity 5
  • CAT. No.D070033
  • CAS. No.97483-11-9
  • Mol. F.C14H17NO2S
  • Mol. W.263.36 g/mol
  • Stock Status:Custom Synthesis
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2-Oxodarifenacin
2-Oxodarifenacin
  • CAT. No.D070035
  • CAS. No.133034-08-9
  • Mol. F.C28H28N2O3.HCl
  • Mol. W.476.99 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin 4-Hydroxy Impurity
Darifenacin 4-Hydroxy Impurity
  • CAT. No.D070036
  • CAS. No.NA
  • Mol. F.C28H31BrN2O2
  • Mol. W.507.46g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 7
Darifenacin Impurity 7
  • CAT. No.D070037
  • CAS. No.NA
  • Mol. F.C19H22N2O 
  • Mol. W.294.40 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin R-Isomer
Darifenacin R-Isomer
  • CAT. No.D070038
  • CAS. No.133099-05-5
  • Mol. F.C28H30N2O2
  • Mol. W.426.55 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Vinyl Impurity
Darifenacin Vinyl Impurity
  • CAT. No.D070039
  • CAS. No.1048979-09-4
  • Mol. F.C28H30N2O2
  • Mol. W.426.55 g/mol
  • Stock Status:Instock
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N-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-2-{1-[2-(2,3dihydrobenzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacectamide hydrobromide
N-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-2-{1-[2-(2,3dihydrobenzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacectamide hydrobromide
  • CAT. No.D070040
  • CAS. No.NA
  • Mol. F.C38H41N2O3Br
  • Mol. W.653.65 g/mol
  • Stock Status:Custom Synthesis
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Darifinacin Bromophenol Impurity
Darifinacin Bromophenol Impurity
  • CAT. No.D070041
  • CAS. No.NA
  • Mol. F.C28H31BrN2O2.HBr
  • Mol. W.507.48 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Pyrrolidinium Dimer Impurity
Darifenacin Pyrrolidinium Dimer Impurity
  • CAT. No.D070042
  • CAS. No.NA
  • Mol. F.C38H41BrN2O3
  • Mol. W.653.65 g/mol
  • Stock Status:Custom Synthesis
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3-Hydroxy Darifenacin (Mixture of Diastereomers)
3-Hydroxy Darifenacin (Mixture of Diastereomers)
  • CAT. No.D070043
  • CAS. No.1285875-62-8
  • Mol. F.C28H30N2O3
  • Mol. W.442.55 g/mol
  • Stock Status:Custom Synthesis
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(3S)-1-Tosyl-,-diphenyl-3-pyrrolidineacetonitrile
(3S)-1-Tosyl-,-diphenyl-3-pyrrolidineacetonitrile
  • CAT. No.D070044
  • CAS. No.133099-09-9
  • Mol. F.C25H24N2O2S
  • Mol. W.416.54 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 9
Darifenacin Impurity 9
  • CAT. No.D070045
  • CAS. No.142935-60-2
  • Mol. F.C10H8O3
  • Mol. W.176.17 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin 4-Hydroxy Impurity Hydrobromide
Darifenacin 4-Hydroxy Impurity Hydrobromide
  • CAT. No.D070046
  • CAS. No.NA
  • Mol. F.C28H31BrN2O2.HBr
  • Mol. W.588.37 g/mol
  • Stock Status:Custom Synthesis
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(S)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetonitrile
(S)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetonitrile
  • CAT. No.D070047
  • CAS. No.133099-11-3
  • Mol. F.C18H18N2
  • Mol. W.262.35 g/mol
  • Stock Status:Custom Synthesis
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2,3-Dihydro-5-Vinylbenzofuran
2,3-Dihydro-5-Vinylbenzofuran
  • CAT. No.D070048
  • CAS. No.633335-97-4
  • Mol. F.C10H10O
  • Mol. W.146.19 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Hydrobromide
Darifenacin Hydrobromide
  • CAT. No.D070049
  • CAS. No.133099-07-7
  • Mol. F.C28H29N2O2Br
  • Mol. W.505.45 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 11
Darifenacin Impurity 11
  • CAT. No.D070050
  • CAS. No.1048979-15-2
  • Mol. F.C27H29NO
  • Mol. W.383.54 g/mol
  • Stock Status:Custom Synthesis
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2-(1-{2-[3-(2-sec-butoxy-ethyl)-4-hydroxy-phenyl]-ethyl}-pyrrolidin-3-yl)-2,2-diphenyl-acetamide
2-(1-{2-[3-(2-sec-butoxy-ethyl)-4-hydroxy-phenyl]-ethyl}-pyrrolidin-3-yl)-2,2-diphenyl-acetamide
  • CAT. No.D070051
  • CAS. No.NA
  • Mol. F.C32H40N2O3
  • Mol. W.500.67 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin EP Impurity E
Darifenacin EP Impurity E
  • CAT. No.D070052
  • CAS. No.1797983-04-0
  • Mol. F.C38H40N2O3
  • Mol. W.572.74 g/mol
  • Stock Status:Custom Synthesis
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2-Hydroxy-4-amino Butanoic Acid
2-Hydroxy-4-amino Butanoic Acid
  • CAT. No.D070053
  • CAS. No.13477-53-7
  • Mol. F.C4H9NO3
  • Mol. W.119.12 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Dimer-1 Impurity
Darifenacin Dimer-1 Impurity
  • CAT. No.D070054
  • CAS. No.NA
  • Mol. F.C38H40N2O3
  • Mol. W.572.70 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity F
Darifenacin Impurity F
  • CAT. No.D070055
  • CAS. No.NA
  • Mol. F.C28H29BrN2O
  • Mol. W.489.45 g/mol
  • Stock Status:Custom Synthesis
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3-(S)-(+)-(1-carbamoyl-1,1-diphenyl methyl)pyrrolidine
3-(S)-(+)-(1-carbamoyl-1,1-diphenyl methyl)pyrrolidine
  • CAT. No.D070056
  • CAS. No.134002-25-8
  • Mol. F.C18H20N2O
  • Mol. W.280.36 g/mol
  • Stock Status:Custom Synthesis
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(R)-2,2-diphenyl-2-(pyrrolidin-3-yl)acetamide 2,3-dihydroxysuccinate
(R)-2,2-diphenyl-2-(pyrrolidin-3-yl)acetamide 2,3-dihydroxysuccinate
  • CAT. No.D070057
  • CAS. No.1092540-94-7
  • Mol. F.C18H20N2O.C4H6O6
  • Mol. W.43.45 g/mol
  • Stock Status:Instock
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3-(1-cyano-1,1-diphenyl)methyl-1-tosyl pyrrolidine
3-(1-cyano-1,1-diphenyl)methyl-1-tosyl pyrrolidine
  • CAT. No.D070059
  • CAS. No.NA
  • Mol. F.C25H24N2O2S
  • Mol. W.416.54 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin cyano Impurity
Darifenacin cyano Impurity
  • CAT. No.D070060
  • CAS. No.1229355-35-4
  • Mol. F.C18H19N2Br
  • Mol. W.343.26 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Nitroso Impurity 1
Darifenacin Nitroso Impurity 1
  • CAT. No.D070061
  • CAS. No.NA
  • Mol. F.C18H19N3O2
  • Mol. W.309.40 g/mol
  • Stock Status:Custom Synthesis
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(S)-1-Nitrosopyrrolidin-3-ol
(S)-1-Nitrosopyrrolidin-3-ol
  • CAT. No.D070062
  • CAS. No.1341219-46-2
  • Mol. F.C4H8N2O2
  • Mol. W.116.12 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Cyano Pyrrolidine Nitroso Impurity
Darifenacin Cyano Pyrrolidine Nitroso Impurity
  • CAT. No.D070063
  • CAS. No.NA
  • Mol. F.C18H17N3O
  • Mol. W.291.40 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 15
Darifenacin Impurity 15
  • CAT. No.D070064
  • CAS. No.NA
  • Mol. F.C28H30N2O3
  • Mol. W.442.55 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Amide Nitroso Impurity
Darifenacin Amide Nitroso Impurity
  • CAT. No.D070066
  • CAS. No.NA
  • Mol. F.C18H19N3O2
  • Mol. W.309.36 g/mol
  • Stock Status:Custom Synthesis
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Darifenacin Impurity 2
Darifenacin Impurity 2
  • CAT. No.D070068
  • CAS. No.2416229-88-2
  • Mol. F.C28H30N2O3
  • Mol. W.442.56 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Darifenacin-D4
Darifenacin-D4
  • CAT. No.D070007
  • CAS. No.1189701-43-6
  • Mol. F.C28H26D4N2O2
  • Mol. W.430.57 g/mol
  • Stock Status:Instock
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