Clozapine

Clozapine is the prototypical atypical antipsychotic with multi-receptor antagonism including dopamine D4 and serotonin receptors, reserved for treatment-resistant schizophrenia due to risk of agranulocytosis requiring mandatory haematological monitoring. Simson Pharma's Clozapine reference standard and impurities support the stringent stability-indicating QC this closely monitored medication requires.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Clozapine Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Clozapine
Clozapine
  • CAT. No.C480000
  • CAS. No.5786-21-0
  • Mol. F.C18H19ClN4
  • Mol. W.326.82 g/mol
  • Stock Status:Instock
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Clozapine EP impurity C
Clozapine EP impurity C
  • CAT. No.C480001
  • CAS. No.6104-71-8
  • Mol. F.C17H17ClN4
  • Mol. W.312.80 g/mol
  • Stock Status:Instock
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Clozapine N-oxide
Clozapine N-oxide
  • CAT. No.C480002
  • CAS. No.34233-69-7
  • Mol. F.C18H19ClN4O
  • Mol. W.342.82 g/mol
  • Stock Status:Instock
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Clozapine EP impurity D
Clozapine EP impurity D
  • CAT. No.C480003
  • CAS. No.65514-71-8
  • Mol. F.C18H21ClN4O
  • Mol. W.344.84 g/mol
  • Stock Status:Limited Stock
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Clozapine EP impurity A
Clozapine EP impurity A
  • CAT. No.C480004
  • CAS. No.50892-62-1
  • Mol. F.C13H9ClN2O
  • Mol. W.244.68 g/mol
  • Stock Status:Instock
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Clozapine EP impurity B
Clozapine EP impurity B
  • CAT. No.C480005
  • CAS. No.263366-81-0
  • Mol. F.C30H24Cl2N6
  • Mol. W.539.46 g/mol
  • Stock Status:Instock
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Clozapine Impurity 10
Clozapine Impurity 10
  • CAT. No.C480009
  • CAS. No.NA
  • Mol. F.C15H11ClN2O2
  • Mol. W.286.71 g/mol
  • Stock Status:Custom Synthesis
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Clozapine Impurity 11
Clozapine Impurity 11
  • CAT. No.C480010
  • CAS. No.NA
  • Mol. F.C20H21ClN4O
  • Mol. W.368.86 g/mol
  • Stock Status:Custom Synthesis
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Clozapine Impurity 5
Clozapine Impurity 5
  • CAT. No.C480011
  • CAS. No.60091-87-4
  • Mol. F.C13H9ClN2O4
  • Mol. W.292.67 g/mol
  • Stock Status:Instock
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1,2-Dimethylpiperazine
1,2-Dimethylpiperazine
  • CAT. No.C480012
  • CAS. No.25057-77-6
  • Mol. F.C6H14N2
  • Mol. W.114.19 g/mol
  • Stock Status:Custom Synthesis
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Clozapine Impurity 9
Clozapine Impurity 9
  • CAT. No.C480013
  • CAS. No.89-61-2
  • Mol. F.C6H3Cl2NO2
  • Mol. W.192.00 g/mol
  • Stock Status:Instock
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Deschloro Clozapine
Deschloro Clozapine
  • CAT. No.C480015
  • CAS. No.1977-07-7
  • Mol. F.C18H20N4
  • Mol. W.292.39 g/mol
  • Stock Status:Instock
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Clozapine Impurity 1
Clozapine Impurity 1
  • CAT. No.C480016
  • CAS. No.69414-55-7
  • Mol. F.C13H8Cl2N2O3
  • Mol. W.311.12 g/mol
  • Stock Status:Custom Synthesis
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Clozapine-D8
Clozapine-D8
  • CAT. No.C480017
  • CAS. No.1185053-50-2
  • Mol. F.C18H11D8ClN4
  • Mol. W.334.88 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Clozapine
N-Nitroso Clozapine
  • CAT. No.C480018
  • CAS. No.156632-03-0
  • Mol. F.C18H18ClN5O
  • Mol. W.355.82 g/mol
  • Stock Status:Instock
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N-Nitroso desmethyl Clozapine impurity
N-Nitroso desmethyl Clozapine impurity
  • CAT. No.C480019
  • CAS. No.NA
  • Mol. F.C17H16ClN5O
  • Mol. W.341.79 g/mol
  • Stock Status:Custom Synthesis
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8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-1(10H)-one
8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-1(10H)-one
  • CAT. No.C480020
  • CAS. No.NA
  • Mol. F.C13H8ClN3O2
  • Mol. W.273.67 g/mol
  • Stock Status:Custom Synthesis
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2-((4-chloro-2-nitrophenyl)(nitroso)amino)benzoic acid
2-((4-chloro-2-nitrophenyl)(nitroso)amino)benzoic acid
  • CAT. No.C480021
  • CAS. No.NA
  • Mol. F.C13H8ClN3O5
  • Mol. W.321.67 g/mol
  • Stock Status:Custom Synthesis
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2-((2-amino-4-chlorophenyl)(nitroso)amino)benzoic acid
2-((2-amino-4-chlorophenyl)(nitroso)amino)benzoic acid
  • CAT. No.C480022
  • CAS. No.NA
  • Mol. F.C13H10ClN3O3
  • Mol. W.291.69 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Clozapine EP Impurity B (possibility 1)
N-Nitroso Clozapine EP Impurity B (possibility 1)
  • CAT. No.C480023
  • CAS. No.NA
  • Mol. F.C30H23Cl2N7O
  • Mol. W.568.50 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Clozapine EP Impurity B (possibility 2)
N-Nitroso Clozapine EP Impurity B (possibility 2)
  • CAT. No.C480024
  • CAS. No.NA
  • Mol. F.C30H22Cl2N8O2
  • Mol. W.597.50 g/mol
  • Stock Status:Custom Synthesis
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Clozapine Impurity 2
Clozapine Impurity 2
  • CAT. No.C480025
  • CAS. No.50373-22-3
  • Mol. F.C13H8Cl2N2
  • Mol. W.263.10 g/mol
  • Stock Status:Custom Synthesis
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Clozapine Impurity 4
Clozapine Impurity 4
  • CAT. No.C480027
  • CAS. No.NA
  • Mol. F.C17H15ClN6O2
  • Mol. W.370.79 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Clozapine Nitroso EP Impurity C
Clozapine Nitroso EP Impurity C
  • CAT. No.C480028
  • CAS. No.NA
  • Mol. F.C17H16ClN5O
  • Mol. W.341.79 g/mol
  • Stock Status:Please Enquire
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Isotope Labelled Compounds

Clozapine-D3
Clozapine-D3
  • CAT. No.C480008
  • CAS. No.1215691-72-7
  • Mol. F.C18H16ClD3N4
  • Mol. W.329.84 g/mol
  • Stock Status:Instock
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Clozapine Impurity 3 D8
Clozapine Impurity 3 D8
  • CAT. No.C480026
  • CAS. No.2733718-84-6
  • Mol. F.C22H17ClD8N4O2
  • Mol. W.420.96 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Clozapine EP Impurity C d8
N-Nitroso Clozapine EP Impurity C d8
  • CAT. No.C480029
  • CAS. No.NA
  • Mol. F.C17H8D8ClN5O
  • Mol. W.349.84 g/mol
  • Stock Status:Custom Synthesis
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