Bosutinib

Bosutinib is a second-generation BCR-ABL tyrosine kinase inhibitor used for chronic myeloid leukaemia, including cases resistant or intolerant to earlier-generation therapies. Simson Pharma's Bosutinib reference standard and impurities support stability-indicating method development for this targeted oncology agent.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Bosutinib Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Bosutinib
Bosutinib
  • CAT. No.B1020000
  • CAS. No.380843-75-4
  • Mol. F.C26H29Cl2N5O3
  • Mol. W.530.45 g/mol
  • Stock Status:Under Synthesis
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Bosutinib Impurity 8
Bosutinib Impurity 8
  • CAT. No.B1020002
  • CAS. No.846023-24-3
  • Mol. F.C10H8Cl2N2O2
  • Mol. W.259.10 g/mol
  • Stock Status:Instock
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Bosutinib Didesmethyl TriHydrochloride Impurity
Bosutinib Didesmethyl TriHydrochloride Impurity
  • CAT. No.B1020003
  • CAS. No.2468737-94-0(freebase)
  • Mol. F.C24H28Cl5N5O3
  • Mol. W.611.78 g/mol
  • Stock Status:Custom Synthesis
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2,4-Dichloro-5-methoxyaniline
2,4-Dichloro-5-methoxyaniline
  • CAT. No.B1020004
  • CAS. No.98446-49-2
  • Mol. F.C26H29Cl2N5O3
  • Mol. W.53.45 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib N-oxide
Bosutinib N-oxide
  • CAT. No.B1020011
  • CAS. No.2468737-96-2
  • Mol. F.C26H29Cl2N5O4
  • Mol. W.546.45 g/mol
  • Stock Status:Instock
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N-Desmethyl Bosutinib
N-Desmethyl Bosutinib
  • CAT. No.B1020012
  • CAS. No.380843-81-2
  • Mol. F.C25H27Cl2N5O3
  • Mol. W.516.42 g/mol
  • Stock Status:Instock
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Bosutinib 4-Chloro 7-Chloropropoxy Impurity
Bosutinib 4-Chloro 7-Chloropropoxy Impurity
  • CAT. No.B1020013
  • CAS. No.214470-68-5
  • Mol. F.C14H12Cl2N2O2
  • Mol. W.311.16 g/mol
  • Stock Status:Instock
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Bosutinib Impurity 8
Bosutinib Impurity 8
  • CAT. No.B1020014
  • CAS. No.380844-49-5
  • Mol. F.C21H18Cl3N3O3
  • Mol. W.466.74 g/mol
  • Stock Status:Instock
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Bosutinib 4-Hydroxy 7-Chloropropoxy Impurity
Bosutinib 4-Hydroxy 7-Chloropropoxy Impurity
  • CAT. No.B1020015
  • CAS. No.214470-66-3
  • Mol. F.C14H13ClN2O3
  • Mol. W.292.72 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Chloro Impurity
Bosutinib Chloro Impurity
  • CAT. No.B1020016
  • CAS. No.492444-39-0
  • Mol. F.C19H23ClN4O2
  • Mol. W.374.86 g/mol
  • Stock Status:Instock
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4-(2,4-Dichloro-5-methoxyphenylamino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile
4-(2,4-Dichloro-5-methoxyphenylamino)-7-hydroxy-6-methoxyquinoline-3-carbonitrile
  • CAT. No.B1020017
  • CAS. No.1460227-29-5
  • Mol. F.C18H13Cl2N3O3
  • Mol. W.390.22 g/mol
  • Stock Status:Custom Synthesis
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4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
4-(2,4-Dichloro-5-methoxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile
  • CAT. No.B1020018
  • CAS. No.380843-12-9
  • Mol. F.C18H13Cl2N3O3
  • Mol. W.390.22 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib (Form-R)
Bosutinib (Form-R)
  • CAT. No.B1020019
  • CAS. No.NA
  • Mol. F.C26H29Cl2N5O3
  • Mol. W.53.45 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Desmethyl Impurity
Bosutinib Desmethyl Impurity
  • CAT. No.B1020020
  • CAS. No.2468737-92-8
  • Mol. F.C25H27Cl2N5O3
  • Mol. W.516.42 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib dimer impurity
Bosutinib dimer impurity
  • CAT. No.B1020021
  • CAS. No.NA
  • Mol. F.C47H46Cl4N8O6
  • Mol. W.960.73 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Regio isomer impurity
Bosutinib Regio isomer impurity
  • CAT. No.B1020022
  • CAS. No.1391063-17-4
  • Mol. F.C26H29CL2N5O3
  • Mol. W.530.45 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Monohydrate
Bosutinib Monohydrate
  • CAT. No.B1020023
  • CAS. No.918639-08-4
  • Mol. F.C26H29Cl2N5O3:H2O
  • Mol. W.548.46 g/mol
  • Stock Status:Instock
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Bosutinib Didesmethyl Impurity
Bosutinib Didesmethyl Impurity
  • CAT. No.B1020024
  • CAS. No.2468737-94-0
  • Mol. F.C24H25Cl2N5O3
  • Mol. W.502.40 g/mol
  • Stock Status:Under Synthesis
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7-(3-Chloropropoxy)-6-methoxy-4-(4-methyl piperazin-1-yl)quinolone-3-carbonitrile
7-(3-Chloropropoxy)-6-methoxy-4-(4-methyl piperazin-1-yl)quinolone-3-carbonitrile
  • CAT. No.B1020025
  • CAS. No.NA
  • Mol. F.C19H23ClN4O3
  • Mol. W.390.86 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Nitroso Impurity
Bosutinib Nitroso Impurity
  • CAT. No.B1020026
  • CAS. No.NA
  • Mol. F.C26H28Cl2N6O4
  • Mol. W.559.44 g/mol
  • Stock Status:Custom Synthesis
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7-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)nitrosoamino)-6-methoxyquinoline-3-carbonitrile
7-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)nitrosoamino)-6-methoxyquinoline-3-carbonitrile
  • CAT. No.B1020027
  • CAS. No.NA
  • Mol. F.C21H17Cl3N4O4
  • Mol. W.495.74 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity II
Bosutinib Impurity II
  • CAT. No.B1020028
  • CAS. No.846023-56-1
  • Mol. F.C26H31Cl2N5O4
  • Mol. W.548.46 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Des NMP Impurity
Bosutinib Des NMP Impurity
  • CAT. No.B1020029
  • CAS. No.2095306-25-3
  • Mol. F.C21H19Cl2N3O3
  • Mol. W.432.30 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso N-Desmethyl Bosutinib
N-Nitroso N-Desmethyl Bosutinib
  • CAT. No.B1020031
  • CAS. No.NA
  • Mol. F.C25H26Cl2N6O4
  • Mol. W.545.42 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Bosutinib Impurity II
N-Nitroso Bosutinib Impurity II
  • CAT. No.B1020032
  • CAS. No.NA
  • Mol. F.C26H30Cl2N6O5
  • Mol. W.577.46 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 31
Bosutinib Impurity 31
  • CAT. No.B1020033
  • CAS. No.NA
  • Mol. F.C19H23ClN4O2
  • Mol. W.374.87 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 12
Bosutinib Impurity 12
  • CAT. No.B1020034
  • CAS. No.773084-45-0
  • Mol. F.C14H16BrNO4
  • Mol. W.342.19 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Dimer Impurity 2
Bosutinib Dimer Impurity 2
  • CAT. No.B1020035
  • CAS. No.2095306-26-4
  • Mol. F.C46H44Cl4N8O6
  • Mol. W.946.71 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 13
Bosutinib Impurity 13
  • CAT. No.B1020036
  • CAS. No.NA
  • Mol. F.C27H31Cl3N5O3
  • Mol. W.579.93 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Propoxy Dimer Impurity
Bosutinib Propoxy Dimer Impurity
  • CAT. No.B1020037
  • CAS. No.2095306-27-5
  • Mol. F.C39H30Cl4N6O6
  • Mol. W.820.51 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib N-Oxide Impurity 2
Bosutinib N-Oxide Impurity 2
  • CAT. No.B1020038
  • CAS. No.NA
  • Mol. F.C26H29Cl2N5O5
  • Mol. W.562.44 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib N-Oxide Impurity 3
Bosutinib N-Oxide Impurity 3
  • CAT. No.B1020039
  • CAS. No.NA
  • Mol. F.C26H29Cl2N5O4
  • Mol. W.546.45 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 2
Bosutinib Impurity 2
  • CAT. No.B1020040
  • CAS. No.7397-28-6
  • Mol. F.C8H6Cl3NO2
  • Mol. W.254.50 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 3
Bosutinib Impurity 3
  • CAT. No.B1020041
  • CAS. No.28443-52-9
  • Mol. F.C8H8ClNO2
  • Mol. W.185.61 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 4
Bosutinib Impurity 4
  • CAT. No.B1020042
  • CAS. No.1307530-78-4
  • Mol. F.C10H9ClN2O2
  • Mol. W.224.64 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 5
Bosutinib Impurity 5
  • CAT. No.B1020043
  • CAS. No.879644-03-8
  • Mol. F.C10H9ClN2O2
  • Mol. W.224.64 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 6
Bosutinib Impurity 6
  • CAT. No.B1020044
  • CAS. No.NA
  • Mol. F.C9H6Cl2N2O2
  • Mol. W.245.06 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 7
Bosutinib Impurity 7
  • CAT. No.B1020045
  • CAS. No.1821033-10-6
  • Mol. F.C10H8Cl2N2O2
  • Mol. W.259.09 g/mol
  • Stock Status:Custom Synthesis
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Bosutinib Impurity 1
Bosutinib Impurity 1
  • CAT. No.B1030011
  • CAS. No.NA
  • Mol. F.C27H31Cl3N5O3.Cl
  • Mol. W.615.38 g/mol
  • Stock Status:Custom Synthesis
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Brigatinib Impurity 4
Brigatinib Impurity 4
  • CAT. No.B1030012
  • CAS. No.28443-52-9
  • Mol. F.C8H8ClNO2
  • Mol. W.185.61 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Bosutinib D8
Bosutinib D8
  • CAT. No.B1020001
  • CAS. No.2733145-45-2
  • Mol. F.C26H21Cl2D8N5O3
  • Mol. W.538.50 g/mol
  • Stock Status:Instock
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Bosutinib D9
Bosutinib D9
  • CAT. No.B1020030
  • CAS. No.380843-75-4 unlabeled
  • Mol. F.C26H20D9Cl2N5O3
  • Mol. W.539.50 g/mol
  • Stock Status:Custom Synthesis
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