Avapritinib

Avapritinib is a selective KIT and PDGFRA tyrosine kinase inhibitor used for PDGFRA exon 18-mutant gastrointestinal stromal tumours and advanced systemic mastocytosis. Simson Pharma's Avapritinib reference standard and impurities support stability-indicating method development for this precision-oncology agent.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Avapritinib Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Avapritinib
Avapritinib
  • CAT. No.A1930000
  • CAS. No.1703793-34-3
  • Mol. F.C26H27FN10
  • Mol. W.498.56 g/mol
  • Stock Status:Instock
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Avapritinib Impurity 1
Avapritinib Impurity 1
  • CAT. No.A1930002
  • CAS. No.1704492-16-9
  • Mol. F.C16H20FN5
  • Mol. W.301.40 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 2
Avapritinib Impurity 2
  • CAT. No.A1930003
  • CAS. No.1703793-32-1
  • Mol. F.C26H27FN10
  • Mol. W.498.60 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 3
Avapritinib Impurity 3
  • CAT. No.A1930004
  • CAS. No.1704496-81-0
  • Mol. F.C17H21FN4
  • Mol. W.300.37 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 4
Avapritinib Impurity 4
  • CAT. No.A1930005
  • CAS. No.NA
  • Mol. F.C16H21N5
  • Mol. W.283.37 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 5
Avapritinib Impurity 5
  • CAT. No.A1930006
  • CAS. No.1703793-31-0
  • Mol. F.C26H27FN10
  • Mol. W.498.56 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib
Avapritinib
  • CAT. No.A1930007
  • CAS. No.1703795-41-8
  • Mol. F.C27H22FN7O
  • Mol. W.479.50 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 7
Avapritinib Impurity 7
  • CAT. No.A1930008
  • CAS. No.1703793-18-3
  • Mol. F.C25H24FN9O
  • Mol. W.4858.50 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 8
Avapritinib Impurity 8
  • CAT. No.A1930009
  • CAS. No.1703794-32-4
  • Mol. F.C10H9N5O
  • Mol. W.215.20 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 9
Avapritinib Impurity 9
  • CAT. No.A1930010
  • CAS. No.1208361-39-0
  • Mol. F.C6H7BrN2O2
  • Mol. W.219.00 g/mol
  • Stock Status:Custom Synthesis
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N-Nitroso Avapritinib impurity 1
N-Nitroso Avapritinib impurity 1
  • CAT. No.A1930011
  • CAS. No.NA
  • Mol. F.C16H19FN6O
  • Mol. W.330.36 g/mol
  • Stock Status:Custom Synthesis
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Avapritinib Impurity 10
Avapritinib Impurity 10
  • CAT. No.A1930012
  • CAS. No.NA
  • Mol. F.C26H27FN10O
  • Mol. W.514.56 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Avapritinib M499 metabolite
Avapritinib M499 metabolite
  • CAT. No.A1930013
  • CAS. No.NA
  • Mol. F.C26H26FN9O
  • Mol. W.499.54 g/mol
  • Stock Status:Instock
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Isotope Labelled Compounds

(13C,2H3)-Avapritinib tetrahydrochloride
(13C,2H3)-Avapritinib tetrahydrochloride
  • CAT. No.A1930001
  • CAS. No.NA
  • Mol. F.C2513CH24D3FN10.4HCl
  • Mol. W.517.15 g/mol
  • Stock Status:Custom Synthesis
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