Ambrisentan

Ambrisentan is a selective endothelin type-A (ETA) receptor antagonist that reduces pulmonary vascular resistance, used in the management of pulmonary arterial hypertension. Simson Pharma's Ambrisentan reference standard and impurities support stability-indicating assay development for this specialised cardiopulmonary therapy.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Ambrisentan Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Ambrisentan
Ambrisentan
  • CAT. No.A670000
  • CAS. No.177036-94-1
  • Mol. F.C22H22N2O4
  • Mol. W.378.42 g/mol
  • Stock Status:Instock
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Ambrisentan R isomer
Ambrisentan R isomer
  • CAT. No.A670003
  • CAS. No.1007358-76-0
  • Mol. F.C22H22N2O4
  • Mol. W.378.43 g/ mol
  • Stock Status:Instock
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Ambrisentan Vinyloxy Impurity
Ambrisentan Vinyloxy Impurity
  • CAT. No.A670006
  • CAS. No.1639429-81-4
  • Mol. F.C20H18N2O
  • Mol. W.302.37 g/mol
  • Stock Status:Instock
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Ambrisentan Hydroxy Acid Impurity (S-isomer)
Ambrisentan Hydroxy Acid Impurity (S-isomer)
  • CAT. No.A670007
  • CAS. No.178306-52-0
  • Mol. F.C16H16O4
  • Mol. W.272.30 g/mol
  • Stock Status:Instock
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Ambrisentan Hydroxy Acid Impurity (R-Isomer)
Ambrisentan Hydroxy Acid Impurity (R-Isomer)
  • CAT. No.A670007A
  • CAS. No.178306-49-5
  • Mol. F.C16H16O4
  • Mol. W.272.30 g/mol
  • Stock Status:Instock
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Ambrisentan Hydroxyester Impurity
Ambrisentan Hydroxyester Impurity
  • CAT. No.A670008
  • CAS. No.177036-78-1
  • Mol. F.C17H18O4
  • Mol. W.286.32 g/mol
  • Stock Status:Instock
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Ambrisentan Sulfonyl Pyrimidine Impurity
Ambrisentan Sulfonyl Pyrimidine Impurity
  • CAT. No.A670009
  • CAS. No.35144-22-0
  • Mol. F.C7H10N2O2S
  • Mol. W.186.23 g/mol
  • Stock Status:Instock
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4,6-Dimethyl-2-hydroxypyrimidine
4,6-Dimethyl-2-hydroxypyrimidine
  • CAT. No.A670010
  • CAS. No.108-79-2
  • Mol. F.C6H8N2O
  • Mol. W.124.14 g/mol
  • Stock Status:Instock
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Ambrisentan Methyl Ester
Ambrisentan Methyl Ester
  • CAT. No.A670011
  • CAS. No.1106685-61-3
  • Mol. F.C23H24N2O4
  • Mol. W.392.45 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Acyl Beta-D-Glucuronide
Ambrisentan Acyl Beta-D-Glucuronide
  • CAT. No.A670012
  • CAS. No.1106685-58-8
  • Mol. F.C28H30N2O10
  • Mol. W.554.55 g/mol
  • Stock Status:Under Synthesis
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Ambrisentan N-oxide
Ambrisentan N-oxide
  • CAT. No.A670013
  • CAS. No.NA
  • Mol. F.C22H22N2O5
  • Mol. W.394.42 g/mol
  • Stock Status:Custom Synthesis
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4-Hydroxymethyl ambrisentan acyl beta-glucuronide
4-Hydroxymethyl ambrisentan acyl beta-glucuronide
  • CAT. No.A670014
  • CAS. No.NA
  • Mol. F.C28H30N2O11
  • Mol. W.570.55 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Impurity 6
Ambrisentan Impurity 6
  • CAT. No.A670015
  • CAS. No.NA
  • Mol. F.C16H16O4
  • Mol. W.272.30 g/mol
  • Stock Status:Instock
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(S)-methyl-2-hydroxy-3-methoxy-3,3-diphenylpropanoate
(S)-methyl-2-hydroxy-3-methoxy-3,3-diphenylpropanoate
  • CAT. No.A670016
  • CAS. No.177036-78-1
  • Mol. F.C17H18O4
  • Mol. W.286.32 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Epoxide
Ambrisentan Epoxide
  • CAT. No.A670017
  • CAS. No.76527-25-8
  • Mol. F.C16H14O3
  • Mol. W.254.28 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Impurity 1
Ambrisentan Impurity 1
  • CAT. No.A670018
  • CAS. No.59209-45-9
  • Mol. F.C10H21ClN2O
  • Mol. W.220.74 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Impurity E
Ambrisentan Impurity E
  • CAT. No.A670019
  • CAS. No.1312092-82-2
  • Mol. F.C21H18N2O3
  • Mol. W.346.38 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Ethyl Ester
Ambrisentan Ethyl Ester
  • CAT. No.A670021
  • CAS. No.1349854-31-4
  • Mol. F.C24H26N2O4
  • Mol. W.406.47 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Methyl Ester Racemate
Ambrisentan Methyl Ester Racemate
  • CAT. No.A670022
  • CAS. No.1240470-84-1
  • Mol. F.C23H24N2O4
  • Mol. W.392.45 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Pyrimidine Ester Impurity
Ambrisentan Pyrimidine Ester Impurity
  • CAT. No.A670023
  • CAS. No.NA
  • Mol. F.C23H24N2O4
  • Mol. W.392.46 g/mol
  • Stock Status:Custom Synthesis
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Rac O-Demethyl Ambrisentan
Rac O-Demethyl Ambrisentan
  • CAT. No.A670024
  • CAS. No.1106685-85-1
  • Mol. F.C21H20N2O4
  • Mol. W.364.40 g/mol
  • Stock Status:Custom Synthesis
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Ambrisentan Acyl Glucuronide (Mixture of Diastereomers)
Ambrisentan Acyl Glucuronide (Mixture of Diastereomers)
  • CAT. No.A670025
  • CAS. No.1106685-82-8
  • Mol. F.C28H30N2O10
  • Mol. W.554.60 g/mol
  • Stock Status:Custom Synthesis
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Metabolites

Ambrisentan 4-Hydroxymethyl Analog Racemate
Ambrisentan 4-Hydroxymethyl Analog Racemate
  • CAT. No.A670002
  • CAS. No.1106685-84-0
  • Mol. F.C22H22N2O5
  • Mol. W.394.42 g/mol
  • Stock Status:Custom Synthesis
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4-hydroxymethyl ambrisentan
4-hydroxymethyl ambrisentan
  • CAT. No.A670026
  • CAS. No.NA
  • Mol. F.C22H22N2O5
  • Mol. W.394.42 g/mol
  • Stock Status:Custom Synthesis
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Isotope Labelled Compounds

Ambrisentan D3
Ambrisentan D3
  • CAT. No.A670001
  • CAS. No.1046116-26-0
  • Mol. F.C22H19D3N2O4
  • Mol. W.381.44 g/mol
  • Stock Status:Instock
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Ambrisentan-D10
Ambrisentan-D10
  • CAT. No.A670004
  • CAS. No.1046116-27-1
  • Mol. F.C22H12D10N2O4
  • Mol. W.388.48 g/mol
  • Stock Status:Custom Synthesis
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Rac-Ambrisentan-D5
Rac-Ambrisentan-D5
  • CAT. No.A670005
  • CAS. No.1392210-85-3
  • Mol. F.C22H17D5N2O4
  • Mol. W.383.45 g/mol
  • Stock Status:Custom Synthesis
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