Adrenaline

Adrenaline (epinephrine) is the body's principal stress-response catecholamine, acting on both alpha- and beta-adrenergic receptors to drive vasoconstriction, bronchodilation and increased cardiac output. It is the first-line emergency treatment for anaphylaxis and cardiac arrest, making absolute reliability of the reference material non-negotiable. Simson Pharma's Adrenaline reference standard and impurities support the stringent QC demanded of this life-saving injectable agent.

Simson Pharma Global Ltd. (UK) and Simson Pharma Global LLC (USA) supply high-quality Adrenaline Reference Standards, pharmacopoeial reference materials, and its related impurities to pharmaceutical manufacturers, CROs, analytical laboratories, universities, and regulatory organizations worldwide. To service the Europe and America market efficiently, Simson Pharma Limited has set up Simson Pharma Global Ltd. in United Kingdom and Simson Pharma Global LLC in USA respectively.

Pharmaceutical Reference Standards / Impurity Standards

Adrenaline Tartrate
L-Adrenaline
Adrenalone Hydrochloride Hydrate
Adrenaline Impurity Mixture
L-(-)-Epinephrine
Adrenaline EP Impurity E
Deoxy Epinephrine Hydrochloride
N-Benzyl Epinephrine
Epinephrine Impurity D Hydrochloride
Adrenaline EP Impurity B
D-Adrenaline
Adrenaline EP Impurity F
(±)-Epinephrine Hydrochloride
Rac-Adrenaline EP Impurity F
Epinephrine Methoxy AnalogHydrochloride
(-)-Epinephrine
N-Methyl Adrenalone Hydrochloride
Adrenalone
Vanillylmandelic Acid
2-chloro-1-(3-hydroxyphenyl)ethanone
Phenylephrine Impurity 7
4-Chlorocatechol
Deoxyepinephrine
Rac Epinephrine-1-Sulfuronthiate
Adrenaline Dimer I
Adrenaline Dimer II
Epinerhrine Impurity 18
Epinephrine Impurity 11
Adrenaline EP Impurity D
(R)-1-methylindoline-3,5,6-triol
(R)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid
Epinephrine Impurity 33
(S)-2-hydroxy-5-(1-hydroxy-2-(methylamino)ethyl)phenyl hydrogen sulfate
1-(3,4-dihydroxyphenyl)-2-(methylamino)ethyl hydrogen sulfate
Adrenaline Impurity 19
4-(2-amino-1-hydroxyethyl)-2-methoxyphenyl hydrogen sulfate
sodium-2-hydroxy-5-(1-hydroxy-2-(methylamino)ethyl)phenyl sulfate
4-(1-hydroxy-2-(methylamino)ethyl)benzene-1,2-diol sulfate
Adrenaline Impurity 2
Epinephrine Impurity 12
Leuco-Adrenochrome
Adrenaline-Quinone
Epinephrine Impurity 10
Epinephrine Sulfate
1-(3,4-dihydroxyphenyl)-2-(ethylamino)ethanone hydrochloride
Adrenalone Impurity 1
Metanephrine
(4R)-2-methyl-1,2,3,4-tetrahydroisoquinoline-4,6,7-triol
(4R)-2-methyl-1,2,3,4-tetrahydroisoquinoline-4,7,8-triol
N-Methyl-5,6-dihydroxyindole
rac Epinephrine-1-Sulfuronthiate Hydrochloride
4-(2-hydroxyacetyl)cyclohexa-3,5-diene-1,2-dione
4-((R)-1-hydroperoxy-2-(methylmino)ethyl)benzene-1,2-diol N-oxide
4-((R)-1-hydroxy-2-(methylmino)ethyl)benzene-1,2-diol N-oxide
2,3-Dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid
2,3-Dihydroxy-6-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid
Epinephrine 4-O-Sulfate
Epinephrine Impurity 8
Epinephrine Impuirty 1
Adrenalone Nitroso Impurity 1
Epinephrine Impurity 18
Epinephrine Impurity 17
Epinephrine Impurity 18
Pseudophenone A
Adrenaline Impurity 18
Epinephrine Impurity 23
Epinephrine Impurity 27
ent-Epinephrine Impurity 25
Epinephrine Impurity 34
Adrenalin-Methylether
Adrenalone Hydrochloride
Epinephrine Impurity 35
Epinephrine Impurity 36
Epinephrine Hydrochloride Impurity 37
Adrenaline EP Impurity E Hydrochloride
Epinerhrine Impurity 19
DL-Normetanephrine Sulfate
Epinerhrine Impurity 20
Epinephrine Impurity 4
Epinephrine Sulfate Impurity
Epinephrine Impurity 5
Epinephrine Impurity 6
Phenylephrine Impurity 8
Adrenaline Nitroso Impurity 1
Epinephrine Impurity 28
Adrenaline Nitroso Impurity 2
Epinephrine Impurity 1
Epinephrine Impurity 2
Epinephrine Impurity 7
Epinephrine Impurity 9
Epinephrine Impurity 13
Epinephrine Impurity 14
Epinephrine Impurity 15
Adrenaline EP Impurity Mixture D & E
Epinephrine Acetate Impurity 29
Adrenaline Impurity 1
Hydroxy Epinephrine Suphate Impurity
6-nitro-N-nitroso adrenaline
Dibutepinephrine
Epinephrine Impurity 16
Adrenaline Impurity 3
Adrenaline Impurity 4
Epinephrine Impurity 28
Epinephrine Melanin Impurity

Metabolites

DL-Epinephrine Beta-D-Glucuronide
DL-Epinephrine Sulphate Sodium Salt

Isotope Labelled Compounds

Epinephrine-D6
N-Benzyl Epinephrine-D3
Rac Metanephrine-D3 Hydrochloride Salt
Rac Normetanephrine-D3 Hydrochloride
Rac-Epinephrine D3
Epinephrine-D3
Rac-Epinephrine D3 Hydrochloride
Dibutepinephrine D3(racemic)